Mycobacterium shottsii: MSHO_47460
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Entry
MSHO_47460 CDS
T07303
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
msho
Mycobacterium shottsii
Pathway
msho00010
Glycolysis / Gluconeogenesis
msho00020
Citrate cycle (TCA cycle)
msho00620
Pyruvate metabolism
msho00785
Lipoic acid metabolism
msho01100
Metabolic pathways
msho01110
Biosynthesis of secondary metabolites
msho01120
Microbial metabolism in diverse environments
msho01200
Carbon metabolism
msho01210
2-Oxocarboxylic acid metabolism
Module
msho_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
msho00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MSHO_47460 (aceE)
00020 Citrate cycle (TCA cycle)
MSHO_47460 (aceE)
00620 Pyruvate metabolism
MSHO_47460 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MSHO_47460 (aceE)
Enzymes [BR:
msho01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MSHO_47460 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
BBX59401
UniProt:
A0A7I7LHA2
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Position
4599356..4602058
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AA seq
900 aa
AA seq
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MASYLPDIDPEETSEWLESFDALLEHSGPARARYLMLRLLERAGEQRVAIPSLTSTDYVN
TIPTELEPWFPGDEDVERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF
NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEKLDGFRQEHSHPGGGLPSYPH
PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRSIKDTSDQHVWCFLGDGEMDEPESR
GLAHMGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD
ALLHADRDGALVNLMNSTPDGDYQTYKANDGAYVRDHFFGRDPRTKALVANMSDQEIWNL
KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALADLKR
FRDSMRIPISDAQLDEDPYLPPYYHPGSDAPEIRYMLDRRRTLGGFLPERPTKTKALTLP
GPDAYKVLKKGSGQQEVATTMALVRTFKELLRDKNIGNRIVPIIPDEARTFGMDSWFPSL
KIYNRNGQLYTAVDAELMLAYKESHIGQILHEGINEAGSVGSFTAAGTSYATHNEPMIPI
YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV
VSYDPAFAYELAYIIENGLSRMFGENPENIYFYITVYNEPYVQPAEPENFDPEGVLRGMY
RYRAATQQCAHKAQLLASGVSMPDALKAAQMLADEWDVATDVWSVTSWSELNRDGVSIER
HRLRHPGEPAGVAYVTTALEGTSGPVVAVSDWMRAVPEQIRPWVPGTYVTLGTDGFGFSD
TRPAARRYFNTDAESQVVAVLEALARDGEIDESVAVTAARQYRIDDVQAAPKQTSDSGVA
NT seq
2703 nt
NT seq
+upstream
nt +downstream
nt
gtggcgtcctacctgcccgatattgaccccgaggaaacttcggaatggctggagtcattc
gacgcactcttggagcactccggaccggcgcgggcgcgctatctgatgctgcgactgctc
gagcgggcaggcgaacagcgcgtcgccatcccgtcattgacctcaacggattacgtcaac
accatccccaccgagttggagccgtggttccccggcgatgaggatgtcgagcgccgctac
cggacctggatcaggtggaacgcggcaatcatggtgcaccgcgcacaacgcccgggcgtc
ggcgtcggtggccacatttcgacctacgcttcgtccgcggccctctacgaagtcggcttc
aaccacttcttccgcggcaaatcgcatcccggcggcggagaccaggtgttcatccagggc
catgcctcccccggcatttacgcccgcgcgttcctggaaggacgactgaccgccgaaaag
ctggacggcttccggcaggaacacagccaccccggcggcgggctaccgtcctacccgcac
ccacggctgatgcccgacttctgggaattcccgaccgtatcgatgggcctgggcccgctc
aacgccatctaccaggcgcggttcaaccactacctgcacgaccgcagcatcaaggacacc
tccgatcagcacgtgtggtgtttcttgggcgacggcgagatggacgagccggagagccgc
gggctggcccacatgggcgccctggaaggcctggacaacctgaccttcgtgatcaactgc
aatctgcaacgcctggacggcccggtccgcggcaacggcaagatcatccaggagctggag
tccttcttccgcggcgcgggctggaacgtcatcaaggtggtctggggccgcgaatgggat
gcgctgctgcacgccgaccgcgacggcgcgctggtgaacctgatgaacagcacccccgac
ggagactaccagacctacaaggccaacgacggcgcctacgtgcgcgatcacttctttggc
cgcgacccccggaccaaggccctggtggccaacatgagcgaccaggagatctggaacctc
aagcgtggcggccacgactaccgcaaggtctatgccgcctaccgcgccgccgtcgaccac
aagggtcagccgacggtgatcctggccaagaccatcaagggctattcgcttggcgcacac
ttccagggccgcaatgccacgcaccagatgaaaaagcttgccctcgccgacctcaagcgg
ttccgggattcgatgcgcatcccgatcagcgacgcccagctcgacgaggacccctaccta
ccgccctactaccacccgggctcggacgccccggagatccgctacatgctggaccggcgc
cgcaccctgggcgggttcctgcccgagcgcccgaccaagaccaaggccctgaccctgccc
ggccccgacgcctacaaggtgctcaagaaggggtccggacaacaagaggtcgccaccacc
atggctctggtccgcaccttcaaagaactgttgcgcgacaagaacatcgggaatcggatt
gtcccgatcattcccgacgaggcccgcaccttcgggatggactcctggttcccgtcgctc
aagatctacaaccgcaatgggcagctatacaccgccgtcgacgcggaactgatgctggcg
tacaaggaaagccacatcggccagatcctgcacgagggcatcaacgaagccgggtcggtg
ggctccttcaccgcggccggcacctcgtatgcgacccacaacgagccgatgatcccgatc
tacatcttctattcgatgttcgggttccagcgcaccggcgacagcttttgggccgcggcc
gaccagatggcgcgcgggttcgtgctgggtgcgaccgctgggcgcaccacgctgaccggt
gagggtctgcaacatgccgatggccactcgctgctgctggccgcgaccaatccggcggtg
gtctcctacgacccggcgtttgcctacgagctcgcctacatcattgaaaatggcctgtct
cggatgttcggggagaacccggagaacatctacttctacatcaccgtctacaacgagccg
tatgtgcagccagcggagccggagaacttcgatcccgagggcgtgctgcgcggcatgtac
cgctaccgtgcggcgacccaacagtgcgcgcacaaggctcagctgctggcttccggggtg
tcgatgcccgacgcgctgaaggcggcgcagatgctggccgacgagtgggacgtcgcgacc
gacgtgtggtcggtgaccagttggagcgagctgaaccgcgacggggtgtccatcgaacgt
caccggctgcgtcaccccggtgaacccgccggtgtcgcctacgtgacgacggcgctggaa
ggcaccagcggcccggtggtcgcggtatcggactggatgcgcgcggttcccgagcagatc
cggccctgggtgcccgggacctacgtcaccctgggcaccgacgggttcggtttctccgac
acccggcccgccgcccgccgctacttcaacaccgatgccgagtcacaggtggtcgcggtg
ctcgaggcgctggcccgcgacggtgagatcgatgagtcggtggccgtcaccgccgcccgt
cagtaccggatcgatgatgtgcaggccgcgccgaagcagacctcggattccggcgtcgca
taa
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