Mycobacterium simiae: MSIM_45200
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Entry
MSIM_45200 CDS
T07396
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
msim
Mycobacterium simiae
Pathway
msim00010
Glycolysis / Gluconeogenesis
msim00020
Citrate cycle (TCA cycle)
msim00620
Pyruvate metabolism
msim00785
Lipoic acid metabolism
msim01100
Metabolic pathways
msim01110
Biosynthesis of secondary metabolites
msim01120
Microbial metabolism in diverse environments
msim01200
Carbon metabolism
msim01210
2-Oxocarboxylic acid metabolism
Module
msim_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
msim00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MSIM_45200 (aceE)
00020 Citrate cycle (TCA cycle)
MSIM_45200 (aceE)
00620 Pyruvate metabolism
MSIM_45200 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MSIM_45200 (aceE)
Enzymes [BR:
msim01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MSIM_45200 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
BBX43069
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Position
complement(4822119..4824824)
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AA seq
901 aa
AA seq
DB search
MASYLPDIDPEETSEWLESFDDLLERSGPARARYLMLRLLERAGEQRVAIPALTSTDYVN
TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGIGVGGHISTYASSAALYEVGF
NHFFRGKTHPGGGDQVFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHPGGGLPSYPH
PRLMHNFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTSDQHVWAFLGDGEMDEPESR
GLIQVAANEALDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD
ALLHADRDGALVNLMNTTPDGDYQTYKANDGAYVRDHFFGRDPRTKALVEPMTDSEIWNL
KRGGHDYRKVYAAYRAAVDHKGQPTVVLAKTIKGYSLGAHFQGRNATHQMKKLALQDLKD
FRDAMRIPVSDAQLEEDAYLPPYYHPGPDAPEIRYMLDRRRTLGGFVPERRTKTRALKQP
AREIYAPLKKGSGNQEVATTMAIVRTFKEVLRDKEIGPRIVPIIPDEARTFGMDSWFPSL
KIYNRNGQLYTAVDAELMLAYKESEVGQILHEGINEAGSTASFTAAGTSYATHNEPMIPI
YIFYSMFGFQRTGDSLWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV
ISYDPAFAFEIAYIVESGLARMFGENPENVYFYITVYNEPYVQPPEPENFDPDGLLRGMY
RFRTATEQRTNKAQILASGIAVPAALKAAEMLAAEWDVAADVWSVTSWSELNRDGVAAQR
EQLRHPDRPVTPPYVAQALAGIEGPVIAVSDWMRAVPELIRPWVPTSYVTLGTDGFGFSD
TRPAARRYFNTDAESQVVAVLEALARDGEIDPSVPVAAARQYKIDDVLAAPKQTSDPGPG
A
NT seq
2706 nt
NT seq
+upstream
nt +downstream
nt
gtggcgtcgtacctgcccgacatcgatcccgaggaaacctcggagtggttggagtccttc
gacgacctgctcgagcggtcggggccggcacgcgctcggtacctgatgttgcggttgcta
gaacgcgccggcgaacagcgggtggccatcccggcgctgacgtcgaccgattacgtcaac
accatccccaccgagttggagccgtggttccccggcgacgaggatgtcgaacgccgctac
cgagcctggatcagatggaacgccgccatcatggtgcatcgcgcccaacgtccgggaatc
ggtgtgggcggccacatttcgacgtatgcgtcgtcggcggcgctctatgaggtcggcttc
aaccacttcttccggggcaagacgcatccgggcggcggcgaccaggtcttcatccagggc
cacgcctcccccggcatctacgcacgcgccttcctggaagggcggctgtccgccgaccag
ctcgacggcttccgccaggagcacagccaccccggcggggggttgccgtcctacccgcat
ccccggctgatgcacaacttctgggaattcccgacggtgtcgatgggcctgggcccgatg
aacgcgatctaccaggctcggttcaaccactacctgcacgaccgcggcatcaaggacacc
tcggatcagcacgtatgggcgttcctcggcgacggcgagatggacgagccggagagccgc
ggactgatccaggtggctgccaacgaggcgctggacaacctgaccttcgtgatcaactgc
aatctgcagcgtctcgacggcccggtgcgcggcaacggcaagatcatccaggagctggag
tcgttcttccgcggcgccggctggaacgtcatcaaggtggtctggggccgcgagtgggac
gcgctgctgcacgccgaccgcgacggcgcactggtgaacctgatgaacaccacgcccgac
ggtgactaccagacgtataaggccaatgacggcgcctacgtccgcgatcacttcttcggc
cgcgacccgcgcaccaaggcactggtcgagcccatgaccgactccgagatctggaacctc
aaacgcggcgggcacgactaccgcaaggtctatgccgcctaccgcgccgccgtcgaccac
aagggccagccgacggtcgtcctcgccaagaccatcaagggctactcgttgggcgcccac
ttccagggccgtaacgccacccatcagatgaaaaagcttgcgctgcaagacctcaaagac
ttccgcgacgccatgcggatcccggtcagtgacgcccagctggaagaggacgcctacctg
ccgccgtattaccaccctggtccggacgccccggagatccgctacatgctggatcggcgc
cgcaccctcggcggtttcgtgcccgagcgtcgcaccaagaccagggcgctcaagcagcct
gcgcgtgagatctatgccccgctgaagaagggatcggggaaccaggaagtcgccaccacg
atggcgatcgtgcgcaccttcaaggaagtgttgcgggacaaggaaatcggtccgcggatc
gtgccgatcattcccgacgaggcccgcaccttcgggatggactcgtggttcccgtcgttg
aagatctacaaccgcaacggccagctctacaccgccgtcgacgccgaattgatgttggcg
tacaaggaaagtgaagtcggccagatactgcacgagggcatcaacgaggcgggctcgacg
gcgtcgttcactgcggcgggcacctcgtacgcgacgcacaacgagccgatgatcccgatc
tacatcttctattcgatgttcgggttccagcgcaccggcgacagcctgtgggccgcggcc
gaccagatggcccgcggcttcgtgctgggcgccaccgcgggccgcaccaccctgaccggc
gaggggctgcagcacgccgacgggcactcgctgctgctggccgccaccaatcccgccgtg
atctcctacgacccggcgttcgcgttcgaaatcgcctacatcgtcgagagcggtctggcc
cggatgttcggcgagaacccggagaacgtgtacttctacatcacggtgtacaacgagccg
tacgtgcagccgccggagccggagaacttcgatcccgacggcctgctgcgcggcatgtat
cggttccgcacggccaccgagcagcgcaccaacaaagcgcagatcctggcctccggcatc
gcggtgccggcggcgttgaaggcggccgagatgctggccgccgagtgggacgtcgccgcc
gatgtgtggtcggtgacgagttggagcgaactcaaccgcgatggggtcgccgcccagcgc
gaacagctgcgccaccccgatcggcccgtcaccccgccgtacgtcgcccaggcgctggcg
ggcatcgagggcccggtaatcgcggtgtcggactggatgcgtgcagtgcccgagctgatc
cggccgtgggtgccgaccagctacgtcacactggggaccgatggcttcggcttctccgac
acccggcccgcggcccggcgctacttcaacaccgacgccgagtcccaggtggtagctgtg
ctggaggcgctggcgcgcgatggcgagatcgacccatcggtgccggtcgcggcggcacgc
cagtacaagatcgacgacgtgctggccgccccgaagcagacctccgatcccggtccgggg
gcgtga
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