Mycolicibacterium smegmatis MC2 155: MSMEG_2471
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Entry
MSMEG_2471 CDS
T00434
Name
(GenBank) pyruvate dehydrogenase alpha subunit
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
msm
Mycolicibacterium smegmatis MC2 155
Pathway
msm00010
Glycolysis / Gluconeogenesis
msm00020
Citrate cycle (TCA cycle)
msm00620
Pyruvate metabolism
msm00785
Lipoic acid metabolism
msm01100
Metabolic pathways
msm01110
Biosynthesis of secondary metabolites
msm01120
Microbial metabolism in diverse environments
msm01200
Carbon metabolism
msm01210
2-Oxocarboxylic acid metabolism
Module
msm_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
msm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MSMEG_2471
00020 Citrate cycle (TCA cycle)
MSMEG_2471
00620 Pyruvate metabolism
MSMEG_2471
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MSMEG_2471
Enzymes [BR:
msm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MSMEG_2471
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Transketolase_N
PDH_E1_M
Transketolase_C_1
Transketolase_C
DXP_synthase_N
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
ABK71799
UniProt:
A0QV73
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Position
complement(2554008..2556437)
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AA seq
809 aa
AA seq
DB search
MSFLLTVAQAGPMSLTAAHTLDVDTARLDTLQQIEQRVLWLSTAMIHHANRVRPNTSGLK
VGGHQASSASMVTIMTALWFEQLRSGDRVSVKPHASPVLHSLNYLLGRLDEKYLTTLRQF
GGLQSYPSRSKDPDPVDYSTGSVGIGATAPIWGAVARRFVDAHYGPTGAGRQYSLVGDAE
LDEGAVWEAILDPGIAELGEVVWIVDLNRQSLDRVVPNIAARRLEKMFDAAGWQVITVKF
GRLLESLFARPGGDALRSRILDMPNPEYQRLLRCTAGDIRTRLPGDGPRSGEIASLIADL
DDQTLTAAIRNLGGHDLAALTQAYREIDDTRPTVIIAYTVKGHGLPTEGHPQNHSALLSH
DEFDALATRLGMDPNAPWQRFAQDSDAGRLCVAAAQRLSRDDITAIDPPAVPGDIGRTPK
GTATTQAALGRVLLDLSREAPDAAARVVTVSPDVSSTTNLGGWVNKVGVWSATERRNWFA
DDAETIMHWDERPSGRHVELGIAETNLVGLLGELGATWSRWGQPLFPIGVLYDPFVERAL
EPWSFGIYAGGQSILVGTPSGVTLAAEGGAHQSIKTPSIGIEQPGCISYEPAFAIDVEWT
LLASMGRLGRPGGTSAYLRLSTRPVDQSLAAVPTDPAARERRRRQVVAGGYPLRRAPGAR
VTIAAMGAVLPEALAAADRLTEQGVPADVVCVTSPGLLFDAWQARQGHDAANTGADTWIL
DQLFPADRALPLVTVLDGHPHTLAFLANIQRVRATNLGVSRFGQVGSLDEVHRYHGLDTD
SIVRAALDVSEGTGVAGFTGVSGITGAGS
NT seq
2430 nt
NT seq
+upstream
nt +downstream
nt
atgagctttctgctcaccgtcgctcaggcaggacccatgtctctcaccgctgcacacacc
ctcgatgtcgacaccgcacgactggacacgctgcaacagatcgaacagcgcgtcctgtgg
ttgtcgaccgcgatgatccatcacgccaaccgggtccgccccaacacctcaggtctcaag
gtcggcggccatcaggcgtcgagcgcgtcgatggtgaccatcatgacggcgctgtggttc
gagcagctccgctcgggtgaccgggtctcggtgaaaccgcacgcctcccccgtgctgcac
agcctgaattacctgttgggcaggctcgacgagaagtacctgacgacgctgcggcagttc
ggcggcctgcagtcctatccgagccggtcgaaggaccctgatcccgtcgactactccacc
ggatcggtgggtatcggtgcgacggccccgatctggggcgcggtggcgcggcggttcgtc
gacgcgcactacgggccgacgggcgcgggcaggcagtactcgctggtgggcgacgccgaa
ctcgacgagggcgcggtgtgggaggccatcctggatcccggtatcgccgagttgggcgag
gtggtctggatcgtcgacctcaaccggcagtccctggaccgtgtggtgcccaacatcgcg
gcgcggcgtctggagaagatgttcgacgccgcgggctggcaggtgatcacggtgaagttc
gggcggctgctggagtcgctgttcgcccggccgggtggcgacgcgttgcgttcacgcatc
ctggacatgccgaatcccgagtaccagcggctgctgcggtgcaccgcgggcgacatccgc
acccgcctgcccggtgacggcccgcgcagcggcgagatcgcttccctgatcgccgatctc
gacgaccagacgctcaccgccgcgatccgcaacctcggcggccatgacctcgcggcgctc
acgcaggcgtaccgcgagatcgacgacacccgtccgacggtgatcatcgcctacacggta
aagggccacggcctgcccaccgaaggccatccgcagaaccactcggcgctgctgtcgcac
gacgagttcgacgcgctggcaacacgtctgggtatggacccgaacgcgccgtggcagcgg
ttcgcccaggacagcgacgccgggcgattgtgcgtcgcggccgcgcaacggctcagccgc
gacgacatcaccgccatcgatccgcccgcggtgcccggcgacatcgggcgcacgcccaag
ggcaccgccaccacgcaggccgcgctgggccgcgtgctgctggacctgtcccgcgaggcg
cccgacgccgcggcacgtgtggtgacggtgagcccggacgtcagttcgacgacgaacctg
ggcggctgggtgaacaaggtgggcgtgtggtctgccaccgaacgccgcaactggttcgcc
gacgacgccgagaccatcatgcactgggacgaacgccccagcggcaggcacgtggaactc
ggtatcgccgagaccaacctggtgggtctgctcggtgagctcggcgcgacctggagtcgt
tggggccagccacttttcccgatcggcgtgctgtacgacccgttcgtcgaacgcgcgctg
gagccgtggtcgttcggcatctacgccggtgggcagtcgatcctcgtgggcaccccgtcg
ggagtcacgctggccgccgagggcggcgcgcaccagtcgatcaagacgccgtcgatcggc
atcgaacaacccggctgcataagctacgaacccgcgttcgccatcgacgtcgagtggacg
ctgctggcgagcatgggccggctgggccgccccggcggcacgtcggcgtatctgcggctc
tcgacgcggcccgtcgatcagtccctggccgcggtgccgaccgaccccgcggcgcgcgaa
cgtcgccgccgccaggtggtggcgggcggctacccgctgcgccgcgccccgggcgcgcgc
gtcacgatcgccgcgatgggcgcggtgctgcccgaggcgctcgcggccgcggaccggctc
accgagcagggcgtgcccgccgacgtggtctgcgtgacgagtcccgggctgctgttcgat
gcgtggcaggcccgccagggtcacgacgctgcgaacaccggcgccgacacctggatcctc
gatcagctgttccccgccgaccgggcgctgccgctggtgaccgtgctggacggacatcca
cacaccctggcgttcctggcgaacatccagcgggtccgggcgaccaacctgggggtgtca
cggttcggccaggtgggctcactcgacgaggtgcaccgctaccacggcctggacaccgac
agcatcgtgcgcgccgcgctcgatgtcagtgagggcaccggggtggccgggttcactggg
gtctctgggatcactggcgccgggagctga
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