Mycolicibacterium smegmatis MC2 155: MSMEG_4323
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Entry
MSMEG_4323 CDS
T00434
Name
(GenBank) pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
msm
Mycolicibacterium smegmatis MC2 155
Pathway
msm00010
Glycolysis / Gluconeogenesis
msm00020
Citrate cycle (TCA cycle)
msm00620
Pyruvate metabolism
msm00785
Lipoic acid metabolism
msm01100
Metabolic pathways
msm01110
Biosynthesis of secondary metabolites
msm01120
Microbial metabolism in diverse environments
msm01200
Carbon metabolism
msm01210
2-Oxocarboxylic acid metabolism
Module
msm_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
msm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MSMEG_4323
00020 Citrate cycle (TCA cycle)
MSMEG_4323
00620 Pyruvate metabolism
MSMEG_4323
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MSMEG_4323
Enzymes [BR:
msm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MSMEG_4323
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ABK72760
UniProt:
A0R0B0
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Position
4407679..4410468
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AA seq
929 aa
AA seq
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MTTEFVRQDLAQNSSTAAEPDRVRVIREGVASYLPDIDTEETAEWLESFDELLERSGPAR
ARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFPGDEDVERRYRAWIRWNAAIM
VHRAQRPGVGVGGHISTYASSATLYEVGFNHFFRGKSHPGGGDHVFIQGHASPGIYARAF
LEGRLTTDQLDGFRQEHSHSGGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHY
LHDRGIKDTSDQHVWAFLGDGEMDEPESRGLIQVAANEALDNLTFVINCNLQRLDGPVRG
NGKIIQELESFFRGAGWNVIKVVWGREWDVLLHADRDGALVNLMNSTPDGDYQTYKANDG
AYVRDHFFGRDPRTKALVADMSDQEIWNLKRGGHDYRKVYAAYRAAMEHKGQPTVILAKT
IKGYTLGQHFEGRNATHQMKKLALEDLKNFRDVTRVPVSDAQLEEDPYLPPYYHPGPEAP
EIRYLLERRRALGGFVPSRRTKSKPLALPGSDTYKALKKGSGSQAVATTMATVRTFKELL
RDKNIGPRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYTSVDSELMLAYKESEVGQILH
EGINEAGSTSSFTAVGTSYSTHDEPMIPIYIFYSMFGFQRTGDGLWAAADQMARGFVLGA
TAGRTTLTGEGLQHADGHSLLLASTNPAAVTYDPAFAYEIAHIIESGLQRMYGEDPENVF
FYLTIYNEPYQQPAEPENLDVEALLKGLYLYRPAPEKRAKSAQILASGVAMPEALRAADL
LASDWDVAADVWSVTSWGELNREGVAIEKHRLRHPDEPAGTPHVTSALADAAGPVIAVSD
WMRAVPEQIRPWVPGTYVTLGTDGFGFSDTRPAARRYFNTDAESVVVAVLQGLARDGEID
ASVAAQAAEQYRIDDVSAAGVSYADTGSA
NT seq
2790 nt
NT seq
+upstream
nt +downstream
nt
ttgaccaccgagttcgtgcgccaggatctggcccaaaactccagcaccgcagcagaaccc
gaccgggtccgggtgatccgtgaaggtgtcgcgtcctacctgccggacatcgacaccgag
gagaccgctgagtggctcgaatccttcgacgagctgctggaacgttccggccctgcgcgt
gcccgttatctgatgctgcgtttgctcgaacgcgccggcgagcagcgtgtcgcgatcccg
gcgctgacgtccaccgattacgtgaacaccatccccaccgagctggaaccgtggttcccc
ggtgacgaggacgtcgagcggcgctaccgcgcctggatccggtggaacgccgcgatcatg
gtgcaccgcgctcagcgtccgggagtcggtgtgggcggtcatatttcgacgtacgcatcg
tcggcgacgctgtacgaggtcggcttcaaccacttcttccgcggcaagagccatcccggc
ggcggggatcatgtgttcatccaggggcacgcctcccccggcatctacgcccgcgcgttc
ctggaaggccggctcacaaccgaccaactggatggtttccgccaggagcacagccactcc
ggcggcggcctgccgtcgtacccgcacccccggctcatgccggacttctgggagttcccg
acggtgtcgatggggctgggccccatgaacgccatctaccaggcgcggttcaaccactac
ctgcacgaccggggtatcaaggacacctccgaccagcacgtgtgggcgttcctcggcgac
ggcgagatggacgaaccggagtcgcgcggcctgatccaggtggccgccaacgaggcgctg
gacaacctgacgttcgtcatcaactgcaacctgcagcgtctcgacggcccggtgcgcggc
aacggcaagatcatccaggaactggagtcgttcttccgcggcgcgggctggaacgtcatc
aaggtcgtgtggggccgcgagtgggacgtgctgctgcacgccgaccgcgacggggcactg
gtcaacctcatgaactccacgcccgacggtgactaccagacctacaaggccaacgacggc
gcgtacgtgcgcgaccacttcttcgggcgcgatccgcgcaccaaggcactggtggccgac
atgtccgaccaggagatctggaatctcaagcgcggcggccacgactaccgcaaggtgtac
gccgcctaccgcgccgcgatggagcacaaggggcagccgacggtcatcctggccaagacc
atcaagggctacacgctggggcagcacttcgagggccgcaacgccacgcaccagatgaaa
aagcttgcgctggaagacctcaagaacttccgcgacgtcacccgcgtgccggtcagcgac
gcccagctcgaagaggacccctacctgccgccgtactaccaccccggtccggaggcgccc
gagatccgttatctgctggagcgccgccgcgcgctcggcgggttcgtgccgtcgcgtcgc
accaagagcaagccgttggccctgccgggcagcgacacctacaaggcgctcaagaagggt
tcgggctcgcaggccgtcgccaccaccatggcgaccgtgcggacgttcaaggagctgttg
cgcgacaagaacatcgggccgcgcatcgtgccgatcatccccgacgaggcgcgcacgttc
ggtatggactcgtggttcccgagcctgaagatctacaaccgcaacgggcagctgtacacg
tcggtggactccgaactgatgctggcctacaaggaatccgaggtcggccagatcctgcac
gagggcatcaacgaggccgggtcgacgtcgtcgttcaccgcggtgggcacgtcgtactcg
acgcacgacgagccgatgatcccgatctacatcttctattcgatgttcggtttccagcgc
accggcgacggcctgtgggccgcagccgatcagatggcccgcgggttcgtgctcggcgcg
acggccgggcgcaccacgctgaccggtgagggcctgcagcacgccgacgggcactcgctg
ctgctggcgtcgaccaacccggccgcggtcacctacgacccggcgttcgcctacgagatc
gcgcacatcatcgagagcggtctgcagcgcatgtacggcgaggatccggagaacgtgttc
ttctacctcaccatctacaacgagccgtatcagcagcctgccgagcccgagaacctcgac
gtcgaggcgctgctgaagggcttgtacctgtaccggcctgccccggagaagcgcgccaag
agcgcgcagatcctggcctccggtgtggcgatgcccgaggcgctgcgcgcggccgacctg
ctcgcgtcggactgggatgtcgccgccgacgtgtggtcggtgaccagctggggcgagctc
aaccgcgagggcgtggcgatcgagaagcaccgtctgcgtcatcccgacgagcccgccggc
acgccccacgtgaccagcgcgctggccgacgcggccggtccggtgatcgcggtgtccgac
tggatgcgggcggtgcccgagcagatccgcccgtgggtgcccggcacctacgtcacgctc
ggtaccgacggcttcggcttctccgacacccggcccgccgcgcgccggtacttcaacacc
gacgccgagtcggtcgtggtggcggtcctgcagggcctggcgcgcgacggcgagatcgac
gcgtcggtcgcggcccaggcggccgagcagtaccgcatcgacgatgtgtccgccgcgggc
gtgtcctacgccgacaccggcagcgcctga
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