Mycolicibacterium gilvum Spyr1: Mspyr1_22210
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Entry
Mspyr1_22210 CDS
T01376
Name
(GenBank) pyruvate dehydrogenase E1 component, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
msp
Mycolicibacterium gilvum Spyr1
Pathway
msp00010
Glycolysis / Gluconeogenesis
msp00020
Citrate cycle (TCA cycle)
msp00620
Pyruvate metabolism
msp00785
Lipoic acid metabolism
msp01100
Metabolic pathways
msp01110
Biosynthesis of secondary metabolites
msp01120
Microbial metabolism in diverse environments
msp01200
Carbon metabolism
msp01210
2-Oxocarboxylic acid metabolism
Module
msp_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
msp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Mspyr1_22210
00020 Citrate cycle (TCA cycle)
Mspyr1_22210
00620 Pyruvate metabolism
Mspyr1_22210
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Mspyr1_22210
Enzymes [BR:
msp01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Mspyr1_22210
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Paralog
Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ADT98871
UniProt:
E6TFF5
LinkDB
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Position
complement(2292027..2294816)
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AA seq
929 aa
AA seq
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MTTEFVRQDLAQNSSSTGEPDRVRVIREGVASYLPDIDPEETGEWLESFDDLLERSGPAR
ARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFPGDEDVERRYRAWIRWNAAIM
VHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKSHPGGGDQVFIQGHASPGIYARAF
LEGRLTTDQLDGFRQEHSHAGGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHY
LHDRDIKDTSKQHVWAFLGDGEMDEPESRGLIQVAANEGLDNLTFVVNCNLQRLDGPVRG
NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDGDYQTYKANDG
SYVRDHFFGRDPRTKALVEPMTDAEIWNLKRGGHDYRKVYAAYHAAMEHKGQPTVILAKT
IKGYTLGKHFEGRNATHQMKKLALQDLKDFRDVQRIPVSDSQLEENPYLPPYYHPGPEAP
EIRYMLDRRRALGGFLPERRTKTKALTLPGRDTYKALKKGSGKQEVATTMATVRTFKELL
RDKNIGWRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESEVGQILH
EGINEAGSTASFTAVGTSYATHNEPMIPIYIFYSMFGFQRTGDGLWAAADQMARGFVLGA
TAGRTTLVGEGLQHADGHSLLLAATNPAVVSYDPAFAFEIAYIIESGLQRMYGDNPENVY
FYMTIYNEPYVQPAEPEGIDVEGLLRGMYRYQAAPQKKSNSAQILVSGVSMPSALKAAEM
LAEEWDVAADVWSVTSWGELNREGVAIEKERLRHPDREVATPYVTEALAGAEGPVVAVSD
WMRAVPEQIRPWVPGTYVTLGTDGFGFSDTRPAARRYYNTDAESIVVAVLEGLARDGNID
ISAAVDAARRYEIDDVMAAPEQTSDPGVA
NT seq
2790 nt
NT seq
+upstream
nt +downstream
nt
ttgaccaccgagttcgtgcgccaggacctggcccaaaactccagcagcacaggcgaaccc
gaccgtgttcgggtcatcagggaaggagtcgcgtcctacctgcccgacatcgaccccgaa
gagaccggcgaatggctcgagtcgttcgacgatctactggaacggtcgggaccggctcgc
gcccggtacctgatgctgcgcctcctcgaacgcgccggtgagcagcgcgtcgccatcccg
gcgctgacctccaccgattacgtgaacaccatcccgacggaactggagccgtggttcccc
ggcgacgaggacgtcgaacgccgttaccgagcgtggatccgctggaacgccgcgatcatg
gtgcaccgcgcccagcgtccgggagtcggtgtcggtggccatatttcgacctacgcgtcg
tcggcggcgctctacgaggtcgggttcaaccacttcttccgcggcaagtcacaccccggc
ggcggtgaccaggtgttcatccagggccacgcctcccccggcatctacgcccgcgccttc
ctcgaaggccgcctgaccaccgaccagctcgacggcttccgccaggagcacagccacgcc
ggcggcgggctgccgtcctatccgcacccccggttgatgcccgatttctgggagttcccc
acggtgtcgatgggtctgggcccgatgaacgcgatctaccaggcccggttcaaccactat
ctgcacgaccgcgacatcaaggacacctcgaagcagcacgtgtgggcgttcctcggcgac
ggcgagatggacgagcccgagagccgcggcctgatccaggtggcggccaacgaggggctc
gacaacctgacgttcgtcgtcaactgcaacctgcagcgcctcgacggcccggtgcgcggc
aacggcaagatcatccaggagctggagtccttcttccgcggcgccggctggaacgtgatc
aaggtggtgtggggccgcgagtgggacgcactgctgcacgccgaccgcgacggcgcgctg
gtcaacctgatgaacaccacccccgacggggactaccagacctacaaggccaacgacggc
agctatgtgcgcgaccatttcttcggccgcgacccccggacgaaggcgctggtcgagccg
atgaccgacgccgagatctggaacctcaaacgcggtggacacgactaccgcaaggtctac
gcggcctaccacgccgcgatggagcacaagggccagccgacggtcatcctcgcgaagacc
atcaagggctacacgctgggtaagcacttcgagggccgcaacgccacccaccagatgaaa
aagcttgcgctccaagacctcaaggatttccgcgacgtccagcgcatcccggtctcggac
tcccagctcgaggagaacccgtacctgccgccgtattaccatccggggccggaagccccc
gagatccggtacatgctcgaccgcagacgcgccctcggcgggttcctgccggagaggcgc
accaagaccaaggcgctcacgctgccgggtcgcgacacctacaaagcgctcaagaagggg
tccggcaagcaggaggtcgccaccacgatggcgaccgtgcgcaccttcaaggaactgttg
cgcgacaagaacatcggatggcgcatcgtgccgatcatccccgacgaggcccgcacgttc
ggcatggactcgtggttcccgtcgctgaagatctacaaccgcaacgggcagctgtacacg
gctgtcgacgcggagctgatgctggcctacaaggagtccgaggtcggccagatcctgcac
gagggcatcaacgaggcggggtcgacggcgtcgttcaccgcggtgggcacctcgtatgcc
acgcacaacgagccgatgatcccgatctacatcttctattcgatgttcggcttccagcgc
accggcgacggcctgtgggcggcggccgaccagatggcccgcggtttcgtgctgggcgcg
accgccgggcgcaccacccttgtcggtgagggccttcagcacgccgacggtcattcgctg
ctgctggcggcgacgaatccggcggtggtgtcctatgacccggcgttcgcgttcgagatc
gcctacatcatcgagagcggcctgcagcgcatgtacggggacaaccccgagaacgtctac
ttctacatgacgatctacaacgagccctacgtgcagccggccgagcccgaaggcatcgac
gtcgagggactgctccgcggcatgtaccgctaccaggcggcgccgcagaagaagtcgaac
tcggcccagatcctcgtgtccggtgtctcgatgccgtcggcgctcaaggccgccgagatg
ctcgccgaggagtgggacgtcgccgccgacgtctggtcggtgaccagctggggcgaactc
aatcgcgagggtgtggccatcgagaaggagcggctgcggcacccggaccgcgaggtggcg
acgccgtatgtcaccgaggcgctcgccggcgccgaaggtccggtcgtcgcggtgtcggac
tggatgcgcgccgtgccggagcagatccggccctgggtgccgggcacctacgtgacgctg
ggtaccgacggtttcggcttcagcgacacccgcccggccgcgcgtcgctactacaacacc
gatgccgagtcgatcgtggtggcggtgctggaaggtctggcccgcgacggcaacatcgac
atctccgcggcggtcgacgcggcgcgccggtacgagatcgacgatgtgatggcggcgccg
gagcagacctcagatcccggcgtggcctga
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