Allomeiothermus silvanus: Mesil_3112
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Entry
Mesil_3112 CDS
T01246
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
msv
Allomeiothermus silvanus
Pathway
msv00010
Glycolysis / Gluconeogenesis
msv00020
Citrate cycle (TCA cycle)
msv00620
Pyruvate metabolism
msv00785
Lipoic acid metabolism
msv01100
Metabolic pathways
msv01110
Biosynthesis of secondary metabolites
msv01120
Microbial metabolism in diverse environments
msv01200
Carbon metabolism
msv01210
2-Oxocarboxylic acid metabolism
Module
msv_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
msv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Mesil_3112
00020 Citrate cycle (TCA cycle)
Mesil_3112
00620 Pyruvate metabolism
Mesil_3112
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Mesil_3112
Enzymes [BR:
msv01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Mesil_3112
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ADH64944
UniProt:
D7BE86
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Position
3160515..3163241
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AA seq
908 aa
AA seq
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MITDTELLEARARLSAEEQIALEDLETKEWIESLEYVLRSAGRDRVVALVEALERYAYKH
GVMVPYKLRTPYINTIPADHEPPYPGDLELERRIANILRWNVIAIVQQANKKAEGIGGHI
STYASIAELMEVGFNHFFRGHGAGMDRDLVFYQGHMSPGVYARSFLEGRFSEDDLAKFRR
DLTPGPGRVVTSYPHPWLMPDYWEFPTVSMGLGPIQAIYQARFMRYLEDRGLKPRSSAKV
WAFLGDGEQDEVETLGALRVAATEELDNLIFVINANLQRLDGPVRGNSKVIQELESVYRG
NGWNVIKVVWGSAWDELLAKDTEGVLLERFEQLVDGESQRYAAYGAKELREKFFNTPALK
KLIEGYTDEDLETLTLSRGGHDVKKVYAAYKAALEHRGSPTVIIARSVKGYGLGPSAQAK
NIAHQVKKLTPEDLREARDFLGIPVSDEDLEKTPFYHPGPDSPEVRYMLERRAALGGLIP
ARKVSFTPLNTPDASFFEEFYQGSGGREISTTMAFVRMLTKLVRHPEVGKYVVPIVPDEA
RTFGMEGVISSVGIYSPKGQLYEPVDAGTVTVYRESKTGQLLQEGINEAGAMASFIAAGT
AYAHYGIPTIPFYIYYSMFGLQRVGDLVWAAGDQRTKGFLLGATAGRTTLNGEGLQHEDG
HSHVLALPVPNMPAYDPAFAYELAVILEEGLRRMYKEGEDIFYYIPLMNENYPQPPMPEP
RAATREGILRGIYRFQESSLKKPKARVQLLGSGTILNEVIEAAKLLEGYGVAADVWSVTS
YKALYYDAIEAARYNRLHPTAKQPKKAYIAQALEGSEGPIIAASDYMKALPELLSGHLDR
PIHSLGTDGFGRSDTRQALRDFFEVDRNHISVAALYMLKQTGKLEAKVVAEAIKQLGIDP
EREAPHKR
NT seq
2727 nt
NT seq
+upstream
nt +downstream
nt
gtgatcacggatactgagctactggaagcgagagccaggctctcggcagaagaacagatt
gccctagaagacctcgagaccaaagagtggatcgagtcgctcgaatatgtactccgctct
gccgggcgcgaccgggtggtggcgctggtggaggcgctcgagcgctacgcctacaagcat
ggggtgatggtgccctacaagctgcgcaccccctacatcaataccattcccgccgatcac
gagcctccctaccccggtgacctcgagctcgagcggcgcatcgccaacatcctgcgctgg
aacgtcatcgccatcgtgcagcaggccaacaagaaggccgagggcatcggcgggcacatc
tctacctacgcctctatcgcggaactgatggaggtgggctttaaccacttcttccgcggg
cacggcgccgggatggaccgcgacctggtgttctaccaagggcacatgtcgcccggggtg
tacgcgcgcagcttcctcgagggccgcttcagcgaggatgacctggccaagttccgccgc
gaccttacgcccggaccgggccgcgtcgtcaccagctacccccacccctggctgatgccc
gactactgggagttccccaccgtctccatgggcctaggacccatccaggccatttaccag
gcccgcttcatgcgctacttggaagaccgcggcctcaagccccgctccagcgccaaggtc
tgggccttcttgggcgacggcgagcaggacgaggtggagaccctgggggcgctgcgggta
gccgccaccgaggagctcgacaacctcatcttcgtcatcaacgccaacctccagcgcctc
gacgggccggtgcgcggcaactccaaggtgatccaggagctggagtcggtctaccggggc
aacggctggaacgtgatcaaggtggtgtggggcagtgcctgggacgagctgttggccaag
gacaccgagggcgtgctgctggagcgcttcgagcagctcgtcgacggggagagccagcgc
tacgcggcctacggggccaaggagttgcgcgagaagttcttcaacacccccgcgctgaaa
aagctcatcgagggctacaccgatgaggatctcgagaccctcaccctctcgcgcggcggt
cacgacgtgaaaaaagtttacgccgcctataaagccgccctcgagcaccgggggagcccc
acggtgatcatcgcccgcagcgtcaagggctacggcttaggccccagcgcccaggccaag
aacatcgcccaccaggtcaagaagctcacccccgaggatctgcgcgaggcgcgggacttc
ctgggtatcccggtctccgatgaggacctggagaagacccccttctaccaccccggcccc
gacagccccgaggtgcggtacatgctcgagcgccgcgcggctctgggcggtctgatcccc
gcgcgcaaggtcagcttcacccccctcaacacccccgatgcctccttcttcgaggagttc
taccagggctcgggcgggcgcgagatctccaccaccatggccttcgtgcgcatgctgacc
aagctggtgcgccaccccgaagtcggcaagtacgtcgtgcccatcgtgcccgacgaggcc
cgcaccttcggcatggagggcgtgatctcctcggtgggtatctatagccccaagggtcag
ctctacgagcccgtggacgcgggcacggtgacggtctaccgcgagtccaagaccggacag
ctgttgcaggagggcatcaacgaggccggggccatggccagcttcatcgccgcgggcacc
gcctacgcccactacggcatccccaccatccccttctatatctactactcgatgttcggc
ctgcaacgggtgggtgatctggtctgggctgcgggcgaccagcgcaccaagggctttttg
ctgggggccaccgccgggcgcaccaccctcaacggcgagggattgcagcacgaggacgga
cactctcacgtgctggcccttccggtgcccaacatgcccgcttatgatccggcttttgcc
tacgagttggcggtgatcctcgaggaaggcctgcgccggatgtacaaagagggggaggac
atcttctactacatccccttgatgaacgagaactacccccaaccccccatgccggaaccg
cgcgcagcaacccgcgagggcatcttgcgggggatttatcgcttccaggagtccagcctt
aaaaaacccaaggcccgggtgcaactcttaggctcagggaccattttgaacgaggtgatc
gaggcagccaagctgctcgagggctatggggtcgccgccgatgtgtggagtgtgaccagc
tacaaggcactctactacgatgccatcgaagcggcccgctataaccggctgcaccccacc
gccaaacaacccaaaaaggcctacatcgcccaagccctagaaggcagtgagggccccatc
atcgccgcctcggattacatgaaggcgctgcccgaactgctctcgggccacttggaccgc
cccatccactccttggggaccgatggctttggccgtagcgatacccgccaggccttgcgc
gacttctttgaggtagaccgcaaccatataagcgtggccgccctctacatgcttaaacaa
accggtaagctcgaggccaaggtggtggctgaagcaattaagcagctgggcatcgacccc
gaacgggaggcgccgcacaagcgctga
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