KEGG   Mycobacterium tuberculosis KZN 1435: TBMG_01856
Entry
TBMG_01856        CDS       T00940                                 
Name
(GenBank) 5-methyltetrahydrofolate-homocystein methyltransferase metH
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
mtb  Mycobacterium tuberculosis KZN 1435
Pathway
mtb00270  Cysteine and methionine metabolism
mtb00450  Selenocompound metabolism
mtb00670  One carbon pool by folate
mtb01100  Metabolic pathways
mtb01110  Biosynthesis of secondary metabolites
mtb01230  Biosynthesis of amino acids
mtb04980  Cobalamin transport and metabolism
mtb04981  Folate transport and metabolism
Module
mtb_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:mtb00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    TBMG_01856
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    TBMG_01856
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    TBMG_01856
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    TBMG_01856
   04980 Cobalamin transport and metabolism
    TBMG_01856
Enzymes [BR:mtb01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     TBMG_01856
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding Na_Ca_ex_C HTH_39
Other DBs
NCBI-ProteinID: ACT24920
LinkDB
Position
2029050..2032628
AA seq 1192 aa
MTAADKHLYDTDLLDVLSQRVMVGDGAMGTQLQAADLTLDDFRGLEGCNEILNETRPDVL
ETIHRNYFEAGADAVETNTFGCNLSNLGDYDIADRIRDLSQKGTAIARRVADELGSPDRK
RYVLGSMGPGTKLPTLGHTEYAVIRDAYTEAALGMLDGGADAILVETCQDLLQLKAAVLG
SRRAMTRAGRHIPVFAHVTVETTGTMLLGSEIGAALTAVEPLGVDMIGLNCATGPAEMSE
HLRHLSRHARIPVSVMPNAGLPVLGAKGAEYPLLPDELAEALAGFIAEFGLSLVGGCCGT
TPAHIREVAAAVANIKRPERQVSYEPSVSSLYTAIPFAQDASVLVIGERTNANGSKGFRE
AMIAEDYQKCLDIAKDQTRDGAHLLDLCVDYVGRDGVADMKALASRLATSSTLPIMLDST
ETAVLQAGLEHLGGRCAINSVNYEDGDGPESRFAKTMALVAEHGAAVVALTIDEEGQART
AQKKVEIAERLINDITGNWGVDESSILIDTLTFTIATGQEESRRDGIETIEAIRELKKRH
PDVQTTLGLSNISFGLNPAARQVLNSVFLHECQEAGLDSAIVHASKILPMNRIPEEQRNV
ALDLVYDRRREDYDPLQELMRLFEGVSAASSKEDRLAELAGLPLFERLAQRIVDGERNGL
DADLDEAMTQKPPLQIINEHLLAGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAYLEPHM
ERSDDDSGKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNIGIKQPIATILEVAEDKS
ADVVGMSGLLVKSTVVMKENLEEMNTRGVAEKFPVLLGGAALTRSYVENDLAEIYQGEVH
YARDAFEGLKLMDTIMSAKRGEAPDENSPEAIKAREKEAERKARHQRSKRIAAQRKAAEE
PVEVPERSDVAADIEVPAPPFWGSRIVKGLAVADYTGLLDERALFLGQWGLRGQRGGEGP
SYEDLVETEGRPRLRYWLDRLSTDGILAHAAVVYGYFPAVSEGNDIVVLTEPKPDAPVRY
RFHFPRQQRGRFLCIADFIRSRELAAERGEVDVLPFQLVTMGQPIADFANELFASNAYRD
YLEVHGIGVQLTEALAEYWHRRIREELKFSGDRAMAAEDPEAKEDYFKLGYRGARFAFGY
GACPDLEDRAKMMALLEPERIGVTLSEELQLHPEQSTDAFVLHHPEAKYFNV
NT seq 3579 nt   +upstreamnt  +downstreamnt
gtgactgcggccgacaagcacctctacgacaccgatctgctcgacgtcttgtcgcagcga
gtgatggtcggcgacggtgcaatgggaacccaactacaggccgcggacctcacgctcgac
gacttccgcggcctggagggctgcaacgagatcctcaacgaaacccgccctgacgtgctg
gaaaccattcaccgcaactatttcgaagcgggcgccgacgccgtcgagacgaacacgttt
ggctgcaacctgtccaacctcggcgactacgacatcgccgacaggatccgcgatctatca
cagaagggcaccgcgatcgcacgccgggtggccgacgagctgggcagtcccgaccgcaag
cgctacgtgctggggtcgatggggccgggcaccaagctgccgactctgggccacaccgaa
tacgcggtgatccgcgacgcctacaccgaggccgcgctgggcatgctggacggcggagcc
gacgccatcctggtggaaacctgccaggacctactgcagctgaaggcggcggtgttgggg
tcgcggcgggcgatgacgcgggccgggcggcacattccggtgtttgcccacgtcaccgtc
gagaccaccggcaccatgctgctgggcagcgagatcggggcggcgttgaccgctgtcgag
ccgctcggtgtggacatgatcggcttgaactgcgcgacgggtccggccgagatgagcgag
cacctgcgccacctgtcccggcacgcccgcatcccggtgtcggtgatgcccaacgccggg
ttgccggtgctgggcgccaagggcgccgaatatccgttgctgcccgacgaattggccgag
gcgctggccggcttcatcgccgagttcgggctctcgctggtcggtggctgctgcggcacc
accccggcccatatccgcgaagtggctgccgcggttgcgaacatcaagcgtcccgagcga
caggtcagctacgagccgtcggtgtcgtcgctgtacaccgcaatcccgttcgcccaggac
gcctcggttctggtgatcggggagcgaacgaacgccaacggctccaagggttttcgtgag
gcgatgatcgccgaggactaccagaagtgcctggacatcgccaaggaccagacccgcgac
ggcgcccacctgctggacctgtgtgtggactacgtgggccgcgacggtgtggccgacatg
aaggcgctggccagccggctggccacgtcctcgacgctgccgatcatgctggactccacc
gaaaccgcggtgctgcaggcgggtttggagcatctgggtggccgttgcgcgatcaactcg
gtgaactacgaggacggcgacggcccggaatcgcgctttgccaagaccatggcgctggtc
gccgagcacggcgcggcggtggtcgcgctgaccatcgacgaagagggccaggcccgcacc
gcgcagaagaaggtcgagatcgccgagcggctgatcaacgacatcaccggcaactggggc
gtcgacgaatcatccatcctcatcgacaccttgacgttcaccatcgccaccggtcaggag
gagtcccgccgcgacggcatcgagaccatcgaggcgatccgcgaactgaaaaagcgccac
ccggatgtgcagaccacacttggtctgtccaacatctcgtttggtctcaatcccgcagcg
cgccaggtgctcaactcggtgttcctgcacgaatgccaagaagcggggctggattcggcg
atcgtgcacgcgtcgaagatcctgccgatgaaccggattcccgaggagcaacgcaacgtc
gccctggatctggtctacgaccgccgccgcgaggactacgatccgctgcaggagctgatg
cggctgttcgaaggcgtgtcggcggcctcctcgaaagaggaccgactggctgaactagct
gggctgccgctgttcgaacggctggcccaacgcatcgtcgacggcgagcgcaacggcctg
gacgccgatctcgacgaggcgatgacgcaaaagccgccgcttcagatcatcaacgaacat
ctgctggccggcatgaagacggtcggcgagctcttcggctccggccagatgcagctgccg
ttcgtgctgcagtcggcggaggtaatgaaagccgccgtcgcgtatctggaaccgcacatg
gagcgctcggacgacgattcgggcaagggacgcatcgtgctggccaccgtcaagggcgac
gtgcacgacatcggcaagaacctggtcgacatcatcttgagcaacaacggctacgaagtg
gtcaacatcggcatcaagcagccaatcgccaccatcctcgaagtcgccgaggacaagagc
gccgacgtggtcggcatgtcgggcctgctggtgaagtcgaccgtggtgatgaaggaaaac
ctcgaggagatgaacacccggggagtcgccgaaaagttcccggtgctgctcggcggcgcg
gcgttgacgcgcagctatgtcgaaaacgacctggccgagatctaccagggcgaagtgcat
tacgcgcgagacgctttcgagggcctgaagttgatggacaccatcatgagcgccaagcgc
ggcgaggcgcccgacgaaaacagcccggaagccattaaggcgcgtgagaaagaagccgaa
cgtaaggcccgccaccagcgatccaaacgcattgccgcacagcgcaaagccgccgaagaa
ccagtcgaggtgcccgaacgctccgatgtcgcggccgacatcgaggtcccggcgccgccg
ttctggggttcgcggatcgtcaagggcctggcggtggccgactacaccggtctgctcgat
gagcgcgcattgtttttgggccagtggggtttacgcggccagcgcggcggtgagggtccg
tcctacgaagatctcgtcgagaccgagggccggccgcggctgcggtactggttggaccgg
ctgtccaccgacggcatcttggcgcacgccgccgtggtgtacggctatttcccggcggtg
tccgagggcaacgacatcgtggtgctcaccgagcccaagcccgacgccccggtgcgctac
cggtttcacttcccgcgccagcagcgcggtcggtttttgtgcattgccgatttcatccgc
tcgcgggagctggccgccgagcgtggcgaggttgacgtgctgccgttccagctggtgacc
atgggtcagccgatcgcggatttcgccaacgagctgttcgcgtccaacgcctaccgcgac
tacctggaggtgcacggtatcggcgtgcagctcaccgaggcgctggccgagtactggcac
cggcggatccgtgaggagctcaagttctccggggatcgggcgatggcggccgaggatccg
gaggcgaaagaagactatttcaagctcggctaccgcggtgctcgctttgccttcggctac
ggcgcatgcccggatctggaggaccgcgccaagatgatggcgctgctggagcccgaacgc
atcggtgtgacgttatccgaggaattacagctgcatcccgaacagtcgaccgacgcgttc
gtcctgcaccatccggaagccaagtacttcaacgtttaa

DBGET integrated database retrieval system