KEGG   Mycobacterium tuberculosis RGTB327: MRGA327_20965
Entry
MRGA327_20965     CDS       T01775                                 
Symbol
guaA
Name
(GenBank) GMP synthase
  KO
K01951  GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
Organism
mtg  Mycobacterium tuberculosis RGTB327
Pathway
mtg00230  Purine metabolism
mtg00983  Drug metabolism - other enzymes
mtg01100  Metabolic pathways
mtg01232  Nucleotide metabolism
Module
mtg_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP
Brite
KEGG Orthology (KO) [BR:mtg00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    MRGA327_20965 (guaA)
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    MRGA327_20965 (guaA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:mtg01002]
    MRGA327_20965 (guaA)
Enzymes [BR:mtg01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.2  GMP synthase (glutamine-hydrolysing)
     MRGA327_20965 (guaA)
Peptidases and inhibitors [BR:mtg01002]
 Cysteine peptidases
  Family C26: gamma-glutamyl hydrolase family
   MRGA327_20965 (guaA)
SSDB
Motif
Pfam: GATase GMP_synt_C NAD_synthase Peptidase_C26 tRNA_Me_trans Asn_synthase QueC ThiI HHH_2 Arginosuc_synth ATP_bind_3
Other DBs
NCBI-ProteinID: AFE18191
LinkDB
Position
complement(3781765..3783294)
AA seq 509 aa
MLVVDFGAQYAQLIARRVREARVFSEVIPHTASIEEIRARQPVALVLSGGPASVYADGAP
KLDPALLDLGVPVLGICYGFQAMAQALGGIVAHTGTREYGRTELKVLGGKLHSDLPEVQP
VWMSHGDAVTAAPDGFDVVASSAGAPVAAFEAFDRRLAGVQYHPEVMHTPHGQQVLSRFL
HDFAGLGAQWTPANIANALIEQVRTQIGDGHAICGLSGGVDSAVAAALVQRAIGDRLTCV
FVDHGLLRAGERAQVQRDFVAATGANLVTVDAAETFLEALSGVSAPEGKRKIIGRQFIRA
FEGAVRDVLDGKTAEFLVQGTLYPDVVESGGGSGTANIKSHHNVGGLPDDLKFTLVEPLR
LLFKDEVRAVGRELGLPEEIVARQPFPGPGLGIRIVGEVTAKRLDTLRHADSIVREELTA
AGLDNQIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAMTADWTRVPYEVLERI
STRITNEVAEVNRVVLDITSKPPATIEWE
NT seq 1530 nt   +upstreamnt  +downstreamnt
gtgttggtggtcgacttcggtgcccaatatgcccagttgattgcccgtcgggttcgagaa
gcacgggttttctccgaggtgattccgcacaccgcctcgatcgaggagatcagggcccgt
cagccggtggcgctcgtgctttccggtggaccggccagtgtctacgccgacggcgctccg
aaactcgatccggcgctactggacctcggtgtaccggttcttggcatctgctacgggttt
caggccatggcgcaggcgctcggggggatcgtcgcccacaccggcactcgcgaatacggt
cggactgaactgaaagtccttggtggcaaactgcattcggatcttcccgaggttcagccg
gtatggatgagtcacggtgacgcggtcacggccgcgccggacggattcgacgtggtggct
agcagcgccggtgccccggtggccgccttcgaggccttcgaccggcgcctggccggggtg
cagtatcacccggaggtgatgcacaccccacacgggcaacaggtgctcagccggtttttg
cacgacttcgccgggctcggcgcccagtggacgcccgccaacatcgccaacgcgctgatc
gagcaggtgcgcacccagatcggcgacggccacgccatctgcgggctatccggcggcgtg
gattccgcggtggccgcggccctggtgcagcgggccatcggcgaccggttgacctgtgtc
ttcgtcgaccacgggctgttgcgcgccggtgagcgggcgcaggtgcaacgcgatttcgtg
gccgccaccggcgccaacctggtcaccgtcgacgcggccgagaccttcctcgaggcgctg
tcgggcgtgagcgcccccgagggcaaacgcaagatcatcggccgtcagttcatccgcgcg
ttcgagggcgcggtgcgggatgtgctggacggtaagactgctgagttcctggtgcagggc
acgctgtatccggatgtggtggagtccggcgggggcagcggcaccgcgaacatcaagagc
caccacaatgtcggcggcctgcccgacgacctgaagttcaccctcgttgagccgctgcgg
ctgctgttcaaagacgaggtgcgcgcggtcgggcgggagttgggtctgccggaggagatc
gtggcgcgccagccgtttccgggaccggggttgggtattcggatcgtcggggaggtcacc
gccaagcggttggatacgctgcggcacgccgattcgatcgtgcgtgaggagctgaccgcg
gcgggcctggacaaccagatctggcagtgtccggtggtgctgttggccgatgtccgctcg
gtgggtgtgcagggtgacggtcgcacctatggccacccgattgtgctgcgtccggtgtcg
agtgaagacgcgatgaccgccgactggacccgggtgccctacgaggtgctcgagcgcatc
tcgacccggatcaccaacgaggtcgccgaggtcaaccgcgtggtgctggacatcaccagc
aagccgcccgccaccatcgagtgggagtag

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