Macaca thibetana thibetana (Pere David's macaque): 126939687
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Entry
126939687 CDS
T08579
Name
(RefSeq) polyunsaturated fatty acid (12S)/(13S)-lipoxygenase, epidermal-type-like
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
mthb
Macaca thibetana thibetana (Pere David's macaque)
Pathway
mthb00590
Arachidonic acid metabolism
mthb01100
Metabolic pathways
mthb01523
Antifolate resistance
mthb04726
Serotonergic synapse
mthb04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
mthb00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
126939687
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
126939687
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
126939687
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
126939687
Enzymes [BR:
mthb01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
126939687
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Gene cluster
GFIT
Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
126939687
NCBI-ProteinID:
XP_050621275
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Position
16:complement(14497064..14503477)
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AA seq
661 aa
AA seq
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MGKYTVRVATGNLFLAGSPNLVQLWLVGEHGEADLGTQLRPVWGKVEFEIDVPLHLGRLL
MVKLRKHNRLLSVDWFCKWISVQGPGTQGEVFFPCYHWVQGHGIICLPEGTARTLSDDPQ
NLFKKYREQELEERRKVYRWGSWKDGLILPIAGNRQPDLPRDERFLEDKDLDFSVSLAKA
LKDMAIKGTLDFINCVKRLEDFKKIFPRGKTALAERVHDSWKNDALFGYQFLNGANPMLL
RRSSRLPARLVLPPGMEDLKTQLEKELQAGSLFEVDFSLLDGVKPNVIIFKPQYVAAPLV
MLKLQPDGRLLPMVIQLQPPRYGCPPPLLFLPSDPPMAWLLAKTWVRSSDFQLHQLQSHL
LRGHLIAEVIAVATMRSLPSLHPIYKLLIPHFRYTMAINTLARSRLVSEGGIFDLVVSTG
SGGHVDILQRATACLTYRSLCPPDDLADRGLLGVKSSLYGQDAIRLWGIISRYVEGMVGL
FYKSDQAVKDDLELQAWCREMTETGLQMAQDRGFPISLESRAQLCHFVTMCIFTCTGQHA
SNHLGQLDWYSWIPNGPCTMRKPPPISKDVTEKDIVDSLPNLHQAHMQKTVTDFLGRRQP
VMVALGQHEEKYFSGPEPQAMLRQFREELAAMDKEIEVRNAVLDLPYEYLRPSMVENSVT
I
NT seq
1986 nt
NT seq
+upstream
nt +downstream
nt
atgggcaagtacacggtccgtgtagccactgggaatttgttcctggcaggctctcccaac
ctggtgcagctgtggctggtgggtgagcacggggaggcagacctagggacgcagctgcga
ccggtgtggggaaaggtggagtttgagatcgacgtccccctgcacctggggcgcctcctg
atggtgaagctgcgcaagcacaaccggctgttgagtgtcgactggttctgcaagtggatc
tcagtgcagggcccgggaacccaaggcgaggtttttttcccctgctaccactgggtgcag
ggccacgggattatctgcctgcccgagggcactgcccggaccctgagtgatgacccccag
aacctgtttaagaagtaccgggaacaggagctcgaagaaagaaggaaggtgtaccggtgg
ggctcctggaaagatgggttaatcctgcctatagcagggaatagacaaccggaccttccc
agggacgagcgattcctcgaggataaggatttagactttagtgtctccctagcaaaagcg
ttgaaggacatggccattaaggggacactggatttcataaattgtgtgaaaaggctggaa
gatttcaaaaaaatattcccacgtggaaagactgccctggctgagcgggttcatgattct
tggaagaatgatgccctctttgggtaccagtttctcaatggtgcaaaccccatgctcctg
aggcgttcttcaaggctccccgcccgcctggtgctgcctccagggatggaagacttgaag
acccagctggagaaagaactccaggctggatctctgtttgaagtggatttctccttgctg
gatggagtcaagcctaatgtcatcatttttaagccgcaatatgtggccgcccctttggtc
atgctgaagcttcagcctgatggaagactcttgcccatggtcatccagctccagccacct
cgatacggatgtcccccacctctgctctttctgccctcggatccccccatggcctggctc
ctggccaagacctgggtccggagctctgatttccagctgcaccagttacagtcacatctg
ctgaggggacacttgattgctgaggttatcgctgtggctacaatgagaagcttgcctagc
ctccatcctatttacaagcttctgatcccccacttccgctacaccatggcgatcaacacc
ctggcccgtagtcgtcttgtctctgaagggggaatttttgacctggtggtgagcactggt
agtgggggccacgtggacattcttcagagagccacagcttgtttgacctatcgttccctc
tgtcctcctgatgacctggctgaccgtggactcctgggtgtgaaatcttctctttatggc
caagatgccatcaggctgtggggaatcatcagccggtacgtggaggggatggttgggctt
ttctacaagagcgaccaagccgtgaaggatgatctagagctgcaggcctggtgcagagag
atgactgagactggactgcagatggcccaagaccgggggttccccatctccttagagtcc
cgggctcagctctgccactttgtcaccatgtgcatcttcacatgcacgggtcagcatgct
tctaaccacctgggtcagctggactggtactcctggatccctaatggcccatgcaccatg
cggaagcccccacccatctccaaggatgtgacagagaaggacatagtggactcactgccc
aatctccaccaggcacatatgcaaaagaccgtcacagacttccttggcagacgtcagcct
gtcatggtggccctggggcagcatgaggagaaatatttctctggccctgagccccaagct
atgctgagacaattccgggaggagctggctgccatggacaaggagattgaggtccggaat
gcagtcctggacctgccctatgaataccttcgacccagcatggtagagaacagcgtgacc
atctga
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