Macaca thibetana thibetana (Pere David's macaque): 126945702
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Entry
126945702 CDS
T08579
Name
(RefSeq) insulin receptor substrate 4
KO
K17446
insulin receptor substrate 4
Organism
mthb
Macaca thibetana thibetana (Pere David's macaque)
Pathway
mthb04022
cGMP-PKG signaling pathway
mthb04068
FoxO signaling pathway
mthb04081
Hormone signaling
mthb04140
Autophagy - animal
mthb04152
AMPK signaling pathway
mthb04211
Longevity regulating pathway
mthb04213
Longevity regulating pathway - multiple species
mthb04910
Insulin signaling pathway
mthb04920
Adipocytokine signaling pathway
mthb04923
Regulation of lipolysis in adipocytes
mthb04930
Type II diabetes mellitus
mthb04935
Growth hormone synthesis, secretion and action
mthb05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
mthb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
126945702
04022 cGMP-PKG signaling pathway
126945702
04152 AMPK signaling pathway
126945702
09133 Signaling molecules and interaction
04081 Hormone signaling
126945702
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
126945702
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
126945702
04923 Regulation of lipolysis in adipocytes
126945702
04920 Adipocytokine signaling pathway
126945702
04935 Growth hormone synthesis, secretion and action
126945702
09149 Aging
04211 Longevity regulating pathway
126945702
04213 Longevity regulating pathway - multiple species
126945702
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
126945702
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
126945702
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Motif
Pfam:
IRS
PH_11
PH_8
PH
Motif
Other DBs
NCBI-GeneID:
126945702
NCBI-ProteinID:
XP_050631790
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All DBs
Position
X:complement(104378870..104395340)
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AA seq
1250 aa
AA seq
DB search
MASCSFTRDQATRRLRGAAAAAAAALAAVVTTPLLSSGTPTALIGTGSSCPGAMWLSTAT
GSRSDSESDEEDLPVGEEVCKRGYLRKQKHGHRRYFVLKLETADAPARLEYYENARKFRH
SVRAAAAAAAAAASGAAIPRLIPPRRVIILYQCFSVSQRADARYRHLIALFTQDEYFAMV
AENESEQESWYLLLSRLILESKRRRCGTLRAQPDGEPAALAAAAAAEPPFYKDVWQVIVK
PRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRST
VIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSISIGAHLLTLLSARRH
LGLLPLEPGGWLRRSRFEQCCHLRAIGDGEDEMLFTRRFLTPSEPVPHSRRGRLHLPRGR
RSRRASSVPASFFHRLAPSPARPPHPAEAPNNGACLSSEVSGSGSGNSGEEGNPQGKEDQ
EGSGGDYMPMNNWGSGNGRGSGGGQGSSGQGSSSHSSGGNQCSGEGQGSRSGQGSSGGQG
SNGQGSGGNQCSGDGHGTAGGQGSGGGQRPGGGHGSGGGKNSGGGKGSGSGKGSDADGER
GKSLKKRSYFGKLTQSKQQHMPPPPPPPPPPPPAGATGGKGKSGGRFRLYFCADRGATKE
RKEAKEVKDAEIPEGAARGPHRARAFDEDEDDPYVPMRPGVAAPLVSSSDYMPMAPQNVS
ASKKRHSRSPFEDSGGYMMMFPRVSPPPAPSPPKAPDTNKEDDSKDNDSESDYMFMAPGA
GAIPKNPRNPQGGSSSKSWSSYFSLPNPFQSSPLGQSDNSEYVPMLPGKFLGRGLDKEVS
YNWGPKDAASKPSGEGSFSKPGDGGSPSKPWDDGSLKNKAKRPNRLSFIAKGYKIKPKPQ
KPTREQREADSSPDYVNIDFAKRESNTPAPSTQGLPGSWGIIADPRQSAFSNYVNVEFGV
LFPNPANDFSDLFRAIPRANPLSLDSARWPLPPLPLSATGSNANEEEGDYIEVIFNSAMT
PVMPLADSAIRYDAETGRIYVVDPFSECCMDISLSPSRCSEPPPVARLLQEEEQERRRPQ
SRSQSFFAAARAAVSAFPTDSLERDLSPSSVPAVTSAAEPTLAVSQVVAAASALAVARGI
GAAAAAAGFDSASARWFQPVANAADTEAVRGAQDVAGGSNPGAHNPSANLARGENQAGGA
AAAAAAPEPPPRSRRVPRPPEREDTDDDDDTYVRMDFTRPDNQFDSPKRE
NT seq
3753 nt
NT seq
+upstream
nt +downstream
nt
atggcgagttgctccttcactcgcgaccaagcgacaagaagactaagaggtgcagcagcg
gcagcagcggcagctctagcagcagtggtgaccaccccgcttctttcctcgggaaccccg
accgcactcattgggaccgggtcgtcttgtccgggagccatgtggctctccacggccact
ggctcccggtcagactccgagtccgacgaggaggacctccccgtcggggaggaagtctgc
aaacgcggctacctgcggaaacagaagcatgggcacaggcgctacttcgtgctcaaactc
gagactgctgacgccccagctcgcctggaatactacgaaaatgccaggaagttccggcac
agtgtccgcgccgcggcggctgcagcagcggcggccgcctctggcgccgcgatcccccgg
ctcattccaccgcgacgcgtgatcatcctataccagtgcttttccgtgagccagagagca
gatgcaaggtaccgacacctcattgcccttttcacccaggacgagtacttcgcgatggtg
gccgagaacgagtcggagcaggaaagctggtacttgctgctcagccgcctcatcctcgag
agcaagcgccgccgctgcggcacgctccgcgcgcagccggacggagagccggccgcgctg
gcggcggcagcggcagcggagccacccttctataaagatgtgtggcaggtaatagtcaaa
cccagggggctggggcacagaaaagagctgagcggcgtgttccggctgtgtctaaccgac
gaggaggttgtgtttgtgagactgaacaccgaagtggccagcgtggtcgtccagctcctg
agcatccgtcgctgtggacactcggagcagtatttcttcttggaagtaggcaggtccacc
gtcatcggtccgggagagctctggatgcaggtcgatgactgtgtggttgcccaaaacatg
catgagctgtttttggagaagatgagagccttgtgtgcagacgaatacagagcccgctgc
cgcagctacagcatcagcatcggcgcccacctgttaaccctgctgtccgctaggaggcac
ctgggcttgctgccgctcgagccgggaggctggctcagaaggtcccgctttgagcagtgt
tgccacctcagggccatcggcgacggggaagacgagatgcttttcaccaggcgtttccta
acacccagcgagcctgtgccccactccaggcgaggaagactgcacctgcccagagggcgc
aggtcaaggagagcgagttcagtgccggccagcttttttcaccgcttagcacccagccca
gcacgtcccccgcaccctgcagaagccccgaacaatggagcttgcctgtcttctgaagtg
tctggctctggctctggcaactctggggaggaaggcaatccccagggcaaagaagatcag
gaaggaagcggaggcgactacatgcccatgaacaattggggctcaggaaatggccggggc
tcaggaggtggccagggctcaagtggccaaggctccagtagccatagctcgggaggaaac
cagtgttcaggcgagggacagggatcccgaagtggtcagggctcaagtggtggccagggc
tcaaatggccagggctcaggaggaaaccagtgctctggagatggccacggcaccgcaggt
gggcaaggttcaggtggtggccagagacctggaggtgggcatggctcaggtggtggcaag
aactctggagggggcaaaggctcaggaagtgggaaaggatccgatgctgatggtgaacgt
ggaaaatctctgaagaaaagatcctattttggcaaattaactcaaagcaagcaacagcac
atgccaccacctccaccacctcctcctccgcccccaccagctggagcaactggtggaaaa
gggaagtctgggggaagattccgactttatttttgtgctgacagaggagccacaaaagag
cgcaaagaagccaaagaagtgaaagatgcagagatcccagaaggtgcagctcgaggtccc
cacagagccagagcttttgatgaagatgaggatgacccatacgtgccaatgaggccaggg
gtggctgcccctcttgtaagctccagtgattatatgccaatggctcctcaaaatgtctct
gcttcaaaaaagcgccactctcgatccccttttgaagattcaggagggtacatgatgatg
tttcccagagtgagcccaccacctgctcccagtcctccaaaagcacctgatactaataaa
gaggatgactcaaaggacaatgacagtgagagtgactacatgtttatggctcctggagcc
ggtgcaattccaaaaaaccccagaaatcctcagggtggctcttcctccaaaagttggagc
tcctacttctctctaccaaacccttttcagagctcacctttgggacagagtgacaacagt
gagtatgtgccaatgttacctggaaagttcctggggaggggcctagacaaagaagtctcc
tataactggggccccaaagatgcagcttcaaagccttcaggtgagggatcattctcaaag
cctggagatgggggatcaccttcaaagccttgggatgatgggtccctaaagaataaggct
aagagacctaaccgactttcttttattgcaaaaggatataaaatcaagccaaaaccacaa
aagcccacacgtgaacagagagaagctgacagctctcctgactacgtcaacatcgacttc
gctaaaagagagagcaatacaccagctccctctactcaaggactaccaggttcgtggggc
ataattgctgaccccagacagtcagccttttctaattatgtgaatgttgagtttggagta
ctatttccaaatccagcaaacgacttctccgatcttttcagagctataccacgtgccaac
cccttatctctggacagtgctaggtggccacttcctccccttcccctgagtgctacaggt
agcaatgctaatgaggaagagggtgactacattgaagtaattttcaactcagcaatgaca
ccagtcatgcctcttgctgacagtgccattcgctacgatgctgaaacaggtcgaatctat
gtggtcgacccattttctgagtgctgtatggatatttctctctcccccagccgatgttct
gaaccaccacctgtagctaggctgctgcaggaggaagagcaggagagaagacgcccacaa
agtcgttctcaaagtttctttgcagcagccagagccgctgtctctgcttttccaacagac
agcctcgagagagacctttccccatcctcagtcccggcggttacttcggctgcggagccg
actttagcggtcagccaagttgtagctgcggcctccgcgctcgccgtagcccggggcatc
ggcgcagcagccgccgctgctggatttgactccgcctctgcccgctggtttcaacctgtt
gctaatgctgctgataccgaagcagtaaggggagcccaagacgttgccggtggctcgaac
cccggagcccacaacccatctgcaaaccttgccagaggtgagaaccaggctggcggggct
gccgctgcagctgccgctcccgaaccaccacctcgcagtcgccgggtgccaagacccccg
gagagagaagatactgacgacgacgacgacacttacgtgagaatggattttaccagacct
gataaccagttcgactctcccaaaagagagtga
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