KEGG   Macaca thibetana thibetana (Pere David's macaque): 126957612
Entry
126957612         CDS       T08579                                 
Name
(RefSeq) dihydrofolate reductase isoform X1
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
mthb  Macaca thibetana thibetana (Pere David's macaque)
Pathway
mthb00670  One carbon pool by folate
mthb00790  Folate biosynthesis
mthb01100  Metabolic pathways
mthb01240  Biosynthesis of cofactors
mthb01523  Antifolate resistance
mthb04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:mthb00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    126957612
   00670 One carbon pool by folate
    126957612
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    126957612
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    126957612
Enzymes [BR:mthb01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     126957612
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 126957612
NCBI-ProteinID: XP_050651680
LinkDB
Position
6:100903305..100928111
AA seq 262 aa
MAAREQGPAGSASPRPQFPGVCGREPAVTLPCAGAGGGASPAQIGTRGRGGHNFAPILTA
RSVLTSGLGGAPAAVMVRSLNCIVAVSQNMGIGKNGDLPWPLLRNEFRYFQRMTTTSSVE
GKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLARSLDDALKLTEQPE
LANKVDMIWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFLPEIDLEKYKLLPEYPG
VLSDVQEEKGIKYKFEVYEKND
NT seq 789 nt   +upstreamnt  +downstreamnt
atggcagcccgggaacagggccctgccgggagcgcgagcccgcggccgcagttcccaggc
gtctgcgggcgcgagcccgccgtgaccctgccgtgcgccggggcggggggcggggcctcg
cctgcacaaataggaacgagagggcggggcggccacaatttcgcgccaatcttgaccgcg
cgttctgttttaactagcgggctcggaggtgctccagctgctgtcatggttcgttcgcta
aactgcatcgtcgctgtgtcccagaacatgggcatcggcaagaacggggacctgccctgg
ccgctgctcaggaatgaattcagatatttccagagaatgaccacaacctcttcagtagaa
ggtaaacagaatctggtgattatgggtaagaagacttggttctccattcctgagaagaat
cgacctttaaagggtagaattaatttagttctcagcagagaactcaaggaacctccacaa
ggagctcattttcttgccagaagtctggatgatgccttaaaacttactgaacaaccagaa
ttagcaaataaagtagacatgatttggatagttggtggcagttctgtttataaggaagcc
atgaatcacccaggccatcttaaactatttgtgacaaggatcatgcaagactttgaaagt
gacacctttcttccagaaattgatttggagaaatataaacttctaccagaatacccaggt
gttctctctgatgtccaagaggagaaaggcattaagtacaaatttgaagtatatgagaag
aatgattaa

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