Mycolicibacterium thermoresistibile: 4412656_03355
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Entry
4412656_03355 CDS
T05542
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mthn
Mycolicibacterium thermoresistibile
Pathway
mthn00020
Citrate cycle (TCA cycle)
mthn00630
Glyoxylate and dicarboxylate metabolism
mthn00785
Lipoic acid metabolism
mthn01100
Metabolic pathways
mthn01110
Biosynthesis of secondary metabolites
mthn01120
Microbial metabolism in diverse environments
mthn01200
Carbon metabolism
mthn01210
2-Oxocarboxylic acid metabolism
Module
mthn_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mthn_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mthn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
4412656_03355 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
4412656_03355 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
4412656_03355 (kgd)
Enzymes [BR:
mthn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
4412656_03355 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
4412656_03355 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
4412656_03355 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
4412656_03355 (kgd)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
SNW19511
LinkDB
All DBs
Position
1:3559073..3562792
Genome browser
AA seq
1239 aa
AA seq
DB search
MYRKFREDPSSVDPSWHEFLVDYSPGTSTDTNRGGNGIPAAATATPISPPEPAPAPPPEP
ASPDGAAKPQTAKTKTARTPSSGDSSAGAAAPAAPKPQEKKPATPARTADSGAELEKQVL
RGPAAAVVRNMDASLEVPTATSVRAIPAKAMIDNRIVINNHLKRTRGGKVSFTHLIGYAV
VQAVKQYPAMNRYFAEIDGKPHLVTPPHVNLGLAIDLQRKEGERQLVVAAIKKAETMGFR
QFVAAYEDIVRRARDGKLTMDDFTGVTISLTNPGTIGTVHSVPRLMAGQGAIVGVGAMEY
PAEFQGASEDRIAELGIGKLVTLTSTYDHRIIQGAESGEFLRIIHELLLDDDFYDEIFRE
LNIPYEPVRWRPDNPDSIEDKNPRVIELIAAYRNRGHLMADIDPLRLDKERFRSHPDLDV
LTHGLTLWDLDREFKVGGFGGSETKKLRDVLGLLRDAYCRHVGIEYTHILEPEQQQWLQE
RIEVKQAKPTVAEQKYILSRLNAAEAFETFLQTKYVGQKRFSLEGAETVIPTMDAVIDQC
AEHGLDEVVIAMPHRGRLNVLANIVGKPYSEIFKEFEGNLNPSQAHGSGDVKYHLGASGT
YIQMFGDNDIEVSLVANPSHLEAVDPVVEGLVRAKQDKLDKQGDDRFSVVPLVLHGDAAF
AGQGVVAETLNMALLRGYRTGGTIHIIVNNQIGFTTSPDDAKSSEYCTDVAKMIGAPIFH
VNGDDPEAAVWVAKLAVDFRQKFHKDVVIDLICYRKRGHNEGDDPSMTQPEMYDAIDAKR
GVRKSYTEALIGRGDISLKEAEDALRDYQGQLERVFNEVRELERHPVEPSESVESAQMIP
RGMDTSVDKAMLARIGDAHVSWPEDFTVHPRVKPVLEKRREMAYEGKVDWAFAELLALGS
LIAEGKTVRLSGQDTRRGTFSQRHAVVIDRKTGEEFTPLQLLTRHPDGTPNGGKFFVYDS
PLSEFAAVGFEYGYSVGNPDALVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSDVVLL
LPHGHEGQGPDHTSGRIERFLQLWAEGSMTIAMPSTPANYFHLLRRHALDGIKRPLIVFT
PKSMLRHKAAVSDLRDFTEAKFRSVLEEPTYVDGDGDRSKVRRLLLCSGKLYYELAARKA
KDKRDDIAIVRIEQLAPLPRRRIAETLDRYPNVEEKFWVQEEPANQGAWPSFGLTLPEML
PGHFTGLKRISRRAMSAPSSGSSKVHAVEQQEIIDEAFA
NT seq
3720 nt
NT seq
+upstream
nt +downstream
nt
atgtatcggaagttccgcgaggatccgtcgtcggtggatccgagttggcacgaattcctc
gtggactattcccccggcaccagtacggacaccaatcgcggcggcaacgggatcccggcc
gccgcgaccgccactccgatctcaccgcccgaacccgcgcccgccccgccccccgaaccc
gccagccctgacggcgccgccaagccacagaccgccaagaccaagaccgccaggaccccg
tcctcaggggattcctccgccggggccgccgcaccggccgccccgaaaccgcaggagaag
aagcccgcaacaccggccaggacggccgacagcggagccgagctcgagaagcaggtgttg
cgcggtcccgccgcggccgtggtgcgcaacatggacgcgtcgctggaggtacccaccgcg
accagcgtgcgcgccatcccggccaaggcgatgatcgacaaccgcatcgtcatcaacaac
cacctcaagcgcacccgcggcggcaaggtcagcttcacccacctgatcggctacgccgtg
gtgcaggcggtcaagcagtacccggcgatgaaccggtacttcgccgagattgacggcaaa
ccccacctcgtcaccccgccgcatgtcaacctcgggttggccatcgacctgcaacgcaag
gaaggtgagcggcagctggtcgtcgccgccatcaagaaagccgagaccatgggcttccgc
cagttcgtcgccgcctacgaggacatcgtccggcgcgcccgcgacggcaagctgaccatg
gacgacttcaccggtgtgacgatctcgctgacgaacccgggcaccatcggcaccgtgcac
tcggtgccgcggctgatggccgggcagggcgcgatcgtcggcgtcggcgcgatggagtat
ccggcggagttccagggcgccagcgaggaccggatcgccgaactcggcatcggcaaactc
gtcacgctgacctcgacctacgaccaccggatcattcagggcgccgagtccggcgagttc
ctgcgcatcatccacgaactgctgctcgacgacgatttctacgacgagatcttccgcgag
ctcaacatcccctacgagccggtccggtggcgcccggacaaccccgactcgatcgaggac
aagaacccgcgggtcatcgaactgatcgcggcgtaccgcaaccgcggccatctgatggcc
gacatcgacccgctgcgtctggacaaggaacggttccgcagccaccccgacctcgacgtc
ctcacccacgggctgacgctgtgggacctggaccgggagttcaaggtcggcggcttcggc
ggttcggagaccaagaagctgcgcgacgtgctggggctgctgcgcgacgcgtactgccgc
cacgtcggcatcgagtacacccacattctcgagcccgaacagcagcagtggctgcaggag
cggatcgaggtcaaacaggccaaacccaccgtcgccgagcagaagtacattctgagccgg
ctcaacgccgcggaagcgttcgaaaccttcctgcagaccaaatacgttggccagaagcgg
ttttcgctggagggcgcggagacggtcatcccgacgatggacgcggtgatcgaccagtgc
gccgagcacggcctcgatgaggtcgtcatcgcgatgccgcaccgcgggcggctcaacgtg
ctggccaacatcgtcggcaagccctactcggagatcttcaaggagttcgagggcaacctg
aacccgtcgcaggcccacggatccggcgacgtgaagtaccacctgggcgcgagcggcacc
tacatccagatgttcggcgacaacgacatcgaggtgtcgctggtggccaacccgtcgcac
ctggaggccgtcgacccggtggtcgagggtctggtccgcgccaaacaggacaagctcgac
aagcagggcgacgaccggttcagcgtggtcccgctggtgctgcacggcgacgcggcgttc
gccggccagggtgtggtcgccgagacgctgaacatggcgctgctgcgcggttaccgcacc
ggcggcaccatccacatcatcgtcaacaaccagatcggcttcaccacctcgccggacgac
gcgaagtcctcggagtactgcaccgatgtggcgaagatgatcggcgcaccgatcttccac
gtcaacggcgacgaccccgaggccgcggtgtgggtggccaagctggccgtggacttccgg
cagaagttccacaaggacgtcgtcatcgacctgatctgctaccgcaagcgcggccacaac
gagggcgacgacccgtcgatgacccagccggagatgtacgacgcgatcgacgccaagcgc
ggcgtgcgcaagagctacaccgaagcgctgatcggccgcggcgacatctcgctgaaggaa
gccgaggacgcgctgcgcgactaccagggtcagctcgagcgcgtgttcaacgaggtgcgt
gagctcgaacgccacccggtcgaaccgagtgagtcggtggagtctgcccagatgatcccg
cgcgggatggacacctccgtcgacaaggcgatgctcgcgcgcatcggcgatgcgcacgtg
tcgtggcccgaggacttcacggtgcatccgcgggtcaagccggtgctggagaagcgccgc
gagatggcctacgagggcaaggtcgactgggcgttcgccgagttgctggcgctcggttca
ctgatcgccgagggcaagacggtgcggttgagcggccaggacacccgccggggcacgttc
agccagcggcacgcggtggtcatcgaccgcaagaccggcgaggagttcaccccgctgcag
ttgctcacccgccatccggacggcacgcccaacggcggcaagttcttcgtctacgactcg
ccgctgtcggagttcgcggcggtgggcttcgagtacggctactcggtcggcaaccccgac
gcgttggtgttgtgggaggcgcagttcggcgacttcgtcaacggcgcgcagtcgatcatc
gacgagttcatctcctccggtgaggccaagtgggggcagctgtcggatgtcgtgctgctg
ctgccgcacgggcatgaggggcaggggccggaccacacctcgggccgtatcgaacggttc
ctgcagctgtgggccgaggggtcgatgacgatcgcgatgccgtcgacgccggccaactac
ttccacctgctgcgccggcatgcgctcgacggcatcaaacgaccgctgatcgtgttcacg
ccgaagtcgatgctgcggcacaaggccgcggtcagcgatctgcgcgacttcaccgaggcc
aagttccgctcggtgctcgaggagccgacctacgtcgacggcgacggcgaccgcagcaag
gtccgccggctgctgttgtgcagcgggaagctgtactacgaactggccgcgcggaaggcc
aaggacaagcgggacgacatcgcgatcgtgcgcatcgaacagctcgccccgctgccgcgg
cggcgcatcgccgagacgctggaccgctacccgaacgtcgaggagaagttctgggtgcag
gaggagccggccaaccagggcgcgtggccgtcgttcggcctgacgttgccggagatgttg
ccgggccacttcaccgggctgaagcggatctcccgtcgggcgatgtcggccccgtcgtcg
ggctcgtcgaaggtgcacgcggtcgagcagcaggagatcatcgacgaggcgttcgcctga
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