Mycobacterium tuberculosis RGTB423: MRGA423_07780
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Entry
MRGA423_07780 CDS
T01994
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mti
Mycobacterium tuberculosis RGTB423
Pathway
mti00020
Citrate cycle (TCA cycle)
mti00630
Glyoxylate and dicarboxylate metabolism
mti00785
Lipoic acid metabolism
mti01100
Metabolic pathways
mti01110
Biosynthesis of secondary metabolites
mti01120
Microbial metabolism in diverse environments
mti01200
Carbon metabolism
mti01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mti00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
MRGA423_07780 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
MRGA423_07780 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MRGA423_07780 (kgd)
Enzymes [BR:
mti01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
MRGA423_07780 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
MRGA423_07780 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
MRGA423_07780 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
MRGA423_07780 (kgd)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AFE12525
LinkDB
All DBs
Position
complement(1390332..1393979)
Genome browser
AA seq
1215 aa
AA seq
DB search
MYRKFRDDPSSVDPKVGTSSWLTTAPNPPPNQLPNQPRVTSPLVAERAAAAAPQAPPKPA
DTAAAGNGVVAALAAKTAVPPPAEGDEVAVLRGAAAAVVKNMSASLEVPTATSVRAVPAK
LLIDNRIVINNQLKRTRGGKISFTHLLGYALVQAVKKFPNMNRHYTEVDGKPTAVTPAHT
NLGLAIDLQGKDGKRSLVVAGIKRCETMRFAQFVTAYEDIVRRARDGKLTTEDFAGVTIS
LTNPGTIGTVHSVPRLMPGQGAIIGVGAMEYPAEFQGASEERIAELGIGKLITLTSTYDH
RIIQGAESGDFLRTIHELLLSDGFWDEVFRELSIPYLPVRWSTDNPDSIVDKNARVMNLI
AAYRNRGHLMADTDPLRLDKARFRSHPDLEVLTHGLTLWDLDRVFKVDGFAGAQYKKLRD
VLGLLRDAYCRHIGVEYAHILDPEQKEWLEQRVETKHVKPTVAQQKYILSKLNAAEAFET
FLQTKYVGQKRFSLEGAESVIPMMDAAIDQCAEHGLDEVVIGMPHRGRLNVLANIVGKPY
SQIFTEFEGNLNPSQAHGSGDVKYHLGATGLYLQMFGDNDIQVSLTANPSHLEAVDPVLE
GLVRAKQDLLDHGSIDSDGQRAFSVVPLMLHGDAAFAGQGVVAETLNLANLPGYRVGGTI
HIIVNNQIGFTTAPEYSRSSEYCTDVAKMIGAPIFHVNGDDPEACVWVARLAVDFRQRFK
KDVVIDMLCYRRRGHNEGDDPSMTNPYMYDVVDTKRGARKSYTEALIGRGDISMKEAEDA
LRDYQGQLERVFNEVRELEKHGVQPSESVESDQMIPAGLATAVDKSLLARIGDAFLALPN
GFTAHPRVQPVLEKRREMAYEGKIDWAFGELLALGSLVAEGKLVRLSGQDSRRGTFSQRH
SVLIDRHTGEEFTPLQLLATNSDGSPTGGKFLVYDSPLSEYAAVGFEYGYTVGNPDAVVL
WEAQFGDFVNGAQSIIDEFISSGEAKWGQLSNVVLLLPHGHEGQGPDHTSARIERFLQLW
AEGSMTIAMPSTPSNYFHLLRRHALDSIQRPLIVFTPKSMLRHKAAVSEIKDFTEIKFRS
VLEEPTYEDGIGDRNKVSRILLTSGKLYYELAARKAKDNRNDLAIVRLEQLAPLPRRRLR
ETLDRYENVKEFFWVQEEPANQGAWPRFGLELPELLPDKLAGIKRISRRAMSAPSSGSSK
VHAVEQQEILDEAFG
NT seq
3648 nt
NT seq
+upstream
nt +downstream
nt
ttgtaccgcaagttccgcgacgacccctcctcggtcgatcccaaagttggcacgagttcc
tggttgactacagccccgaacccacctcccaaccagctgccgaaccaaccccgggttacc
tcgccactcgttgccgagcgggccgctgcggccgccccgcaggcaccccccaagccggcc
gacaccgcggccgcgggcaacggcgtggtcgccgcactggccgccaaaactgccgttccc
ccgccagccgaaggtgacgaggtagcggtgctgcgcggcgccgccgcggccgtcgtcaag
aacatgtccgcgtcgttggaggtgccgacggcgaccagcgtccgggcggtcccggccaag
ctactgatcgacaaccggatcgtcatcaacaaccagttgaagcggacccgcggcggcaag
atctcgttcacgcatttgctgggctacgccctggtgcaggcggtgaagaaattcccgaac
atgaaccggcactacaccgaagtcgacggcaagcccaccgcggtcacgccggcgcacacc
aatctcggcctggcgatcgacctgcaaggcaaggacgggaagcgttccctggtggtggcc
ggcatcaagcggtgcgagaccatgcgattcgcgcagttcgtcacggcctacgaagacatc
gtacgccgggcccgcgacggcaagctgaccactgaagactttgccggcgtgacgatttcg
ctgaccaatcccggaaccatcggcaccgtgcattcggtgccgcggctgatgcccggccag
ggcgccatcatcggcgtgggcgccatggaataccccgccgagtttcaaggcgccagcgag
gaacgcatcgccgagctgggcatcggcaaattgatcactttgacctccacctacgaccac
cgcatcatccagggcgcggaatcgggcgacttcctgcgcaccatccacgagttgctgctc
tcggatggcttctgggacgaggtcttccgcgaactgagcatcccatatctgccggtgcgc
tggagcaccgacaaccccgactcgatcgtcgacaagaacgctcgcgtcatgaacttgatc
gcggcctaccgcaaccgcggccatctgatggccgataccgacccgctgcggttggacaaa
gctcggttccgcagtcaccccgacctcgaagtgctgacccacggcctgacgctgtgggat
ctcgatcgggtgttcaaggtcgacggctttgccggtgcgcagtacaagaaactgcgcgac
gtgctgggcttgctgcgcgatgcctactgccgccacatcggcgtggagtacgcccatatc
ctcgaccccgaacaaaaggagtggctcgaacaacgggtcgagaccaagcacgtcaaaccc
actgtggcccaacagaaatacatcctcagcaagctcaacgccgccgaggcctttgaaacg
ttcctacagaccaagtacgtcggccagaagcggttctcgctggaaggcgccgaaagcgtg
atcccgatgatggacgcggcgatcgaccagtgcgctgagcacggcctcgacgaggtggtc
atcgggatgccgcaccggggccggctcaacgtgctggccaacatcgtcggcaagccgtac
tcgcagatcttcaccgagttcgagggcaacctgaatccgtcgcaggcgcacggctccggt
gacgtcaagtaccacctgggcgccaccgggctgtacctgcagatgttcggcgacaacgac
attcaggtgtcgctgaccgccaacccgtcgcatctggaggccgtcgacccggtgctggag
ggattggtgcgggccaagcaggatctgctcgaccacggaagcatcgacagcgacggccaa
cgggcgttctcggtggtgccgctgatgttgcatggcgatgccgcgttcgccggtcagggt
gtggtcgccgagacgctgaacctggcgaatctgccgggctaccgcgtcggcggcaccatc
cacatcatcgtcaacaaccagatcggcttcaccaccgcgcccgagtattccaggtccagc
gagtactgcaccgacgtcgcaaagatgatcggggcaccgatctttcacgtcaacggcgac
gacccggaggcgtgtgtctgggtggcgcggttggcggtggacttccgacaacggttcaag
aaggacgtcgtcatcgacatgctgtgctaccgccgccgcgggcacaacgagggtgacgac
ccgtcgatgaccaacccctacatgtacgacgtcgtcgacaccaagcgcggggcccgcaaa
agctacaccgaagccctgatcggacgtggcgacatctcgatgaaggaggccgaggacgcg
ctgcgcgactaccagggccagctggaacgggtgttcaacgaagtgcgcgagctggagaag
cacggtgtgcagccgagcgagtcggtcgagtccgaccagatgattcccgcggggctggcc
actgcggtggacaagtcgctgctggcccggatcggcgatgcgttcctcgccttgccgaac
ggcttcaccgcgcacccgcgagtccaaccggtgctggagaagcgccgggagatggcctat
gaaggcaagatcgactgggcctttggcgagctgctggcgctgggctcgctggtggccgaa
ggcaagctggtgcgcttgtcggggcaggacagccgccgcggcaccttctcccagcggcat
tcggttctcatcgaccgccacactggcgaggagttcacaccactgcagctgctggcgacc
aactccgacggcagcccgaccggcggaaagttcctggtctacgactcgccactgtcggag
tacgccgccgtcggcttcgagtacggctacactgtgggcaatccggacgccgtggtgctc
tgggaggcgcagttcggcgacttcgtcaacggcgcgcagtcgatcatcgacgagttcatc
agctccggtgaggccaagtggggccaattgtccaacgtcgtgctgctgttaccgcacggg
cacgaggggcagggacccgaccacacttctgcccggatcgaacgcttcttgcagttgtgg
gcggaaggttcgatgaccatcgcgatgccgtcgactccgtcgaactacttccacctgcta
cgccggcatgccctggacagcatccaacgcccgctgatcgtgttcacgcccaagtcgatg
ttgcgtcacaaggccgccgtcagcgaaatcaaggacttcaccgagatcaagttccgctca
gtgctggaggaacccacctatgaggacggcatcggagaccgcaacaaggtcagccggatc
ctgctgaccagtggcaagctgtattacgagctggccgcccgcaaggccaaggacaaccgc
aatgacctcgcgatcgtgcggcttgaacagctcgccccgctgcccaggcgtcgactgcgt
gaaacgctggaccgctacgagaacgtcaaggagttcttctgggtccaagaggaaccggcc
aaccagggtgcgtggccgcgattcgggctcgaactacccgagctgctgcctgacaagttg
gccgggatcaagcgaatctcgcgccgggcgatgtcagccccgtcgtcaggctcgtcgaag
gtgcacgccgtcgaacagcaggagatcctcgacgaggcgttcggctga
DBGET
integrated database retrieval system
