Mycobacterium tuberculosis RGTB423: MRGA423_18565
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Entry
MRGA423_18565 CDS
T01994
Symbol
leuD
Name
(GenBank) isopropylmalate isomerase small subunit
KO
K01704
3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mti
Mycobacterium tuberculosis RGTB423
Pathway
mti00290
Valine, leucine and isoleucine biosynthesis
mti00660
C5-Branched dibasic acid metabolism
mti01100
Metabolic pathways
mti01110
Biosynthesis of secondary metabolites
mti01210
2-Oxocarboxylic acid metabolism
mti01230
Biosynthesis of amino acids
Module
mti_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mti00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MRGA423_18565 (leuD)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MRGA423_18565 (leuD)
Enzymes [BR:
mti01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MRGA423_18565 (leuD)
4.2.1.35 (R)-2-methylmalate dehydratase
MRGA423_18565 (leuD)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Aconitase_C
Motif
Other DBs
NCBI-ProteinID:
AFE14129
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All DBs
Position
complement(3338256..3338852)
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AA seq
198 aa
AA seq
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MEAFHTHSGIGVPLRRSNVDTDQIIPAVFLKRVTRTGFEDGLFAGWRSDPAFVLNLSPFD
RGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFGDIFRGNAGKAGLLAAEVAQDDV
ELLWKLIEQSPGLEITANLQDRIITAATVVLPFKIDDHSAWRLLEGLDDIALTLRKLDEI
EAFEGACAYWKPRTLPAP
NT seq
597 nt
NT seq
+upstream
nt +downstream
nt
atggaagcctttcacacccactctggtattggcgtgccgttgcggcggtccaatgtcgac
accgatcagatcattcccgcggtctttctgaagcgggtcacccgaaccggtttcgaggac
ggcttgttcgcgggttggcggtcggatcctgcattcgtgctaaacctcagtccctttgac
cggggttcggtcctggttgccgggcccgatttcggcaccggatcctcgcgagagcatgcg
gtctgggcgctcatggactacggattccgggtggttatctcatcccgatttggtgacatt
ttccgcggcaacgcgggcaaggccgggctgctggcggccgaggttgcccaagacgatgtg
gaactcctgtggaagctcattgagcagagtccgggcctggaaatcactgccaatcttcaa
gatcgaattatcaccgcagcaacagtggtgctgccgttcaagattgacgaccactcggcg
tggcggctgcttgaaggtctcgacgatatagcccttacgctgcggaaactcgacgagatc
gaggcctttgagggtgcgtgcgcgtactggaaaccgcgcactctacccgccccctga
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