Mycobacterium tuberculosis CTRI-2: MTCTRI2_3046
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Entry
MTCTRI2_3046 CDS
T01993
Symbol
leuD
Name
(GenBank) isopropylmalate isomerase small subunit
KO
K01704
3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mto
Mycobacterium tuberculosis CTRI-2
Pathway
mto00290
Valine, leucine and isoleucine biosynthesis
mto00660
C5-Branched dibasic acid metabolism
mto01100
Metabolic pathways
mto01110
Biosynthesis of secondary metabolites
mto01210
2-Oxocarboxylic acid metabolism
mto01230
Biosynthesis of amino acids
Module
mto_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mto00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MTCTRI2_3046 (leuD)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MTCTRI2_3046 (leuD)
Enzymes [BR:
mto01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MTCTRI2_3046 (leuD)
4.2.1.35 (R)-2-methylmalate dehydratase
MTCTRI2_3046 (leuD)
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Gene cluster
GFIT
Motif
Pfam:
Aconitase_C
Motif
Other DBs
NCBI-ProteinID:
AEN01452
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All DBs
Position
complement(3340488..3341084)
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AA seq
198 aa
AA seq
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MEAFHTHSGIGVPLRRSNVDTDQIIPAVFLKRVTRTGFEDGLFAGWRSDPAFVLNLSPFD
RGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFGDIFRGNAGKAGLLAAEVAQDDV
ELLWKLIEQSPGLEITANLQDRIITAATVVLPFKIDDHSAWRLLEGLDDIALTLRKLDEI
EAFEGACAYWKPRTLPAP
NT seq
597 nt
NT seq
+upstream
nt +downstream
nt
atggaagcctttcacacccactctggtattggcgtgccgttgcggcggtccaatgtcgac
accgatcagatcattcccgcggtctttctgaagcgggtcacccgaaccggtttcgaggac
ggcttgttcgcgggttggcggtcggatcctgcattcgtgctaaacctcagtccctttgac
cggggttcggtcctggttgccgggcccgatttcggcaccggatcctcgcgagagcatgcg
gtctgggcgctcatggactacggattccgggtggttatctcatcccgatttggtgacatt
ttccgcggcaacgcgggcaaggccgggctgctggcggccgaggttgcccaagacgatgtg
gaactcctgtggaagctcattgagcagagtccgggcctggaaatcactgccaatcttcaa
gatcgaattatcaccgcagcaacagtggtgctgccgttcaagattgacgaccactcggcg
tggcggctgcttgaaggtctcgacgatatagcccttacgctgcggaaactcgacgagatc
gaggcctttgagggtgcgtgcgcgtactggaaaccgcgcactctacccgccccctga
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