Mycobacterium tuberculosis H37Rv: Rv2476c
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Entry
Rv2476c CDS
T00015
Symbol
gdh
Name
(RefSeq) NAD-dependent glutamate dehydrogenase
KO
K15371
glutamate dehydrogenase [EC:
1.4.1.2
]
Organism
mtu
Mycobacterium tuberculosis H37Rv
Pathway
mtu00220
Arginine biosynthesis
mtu00250
Alanine, aspartate and glutamate metabolism
mtu00430
Taurine and hypotaurine metabolism
mtu00910
Nitrogen metabolism
mtu01100
Metabolic pathways
mtu01120
Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:
mtu00001
]
09100 Metabolism
09102 Energy metabolism
00910 Nitrogen metabolism
Rv2476c (gdh)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
Rv2476c (gdh)
00220 Arginine biosynthesis
Rv2476c (gdh)
09106 Metabolism of other amino acids
00430 Taurine and hypotaurine metabolism
Rv2476c (gdh)
Enzymes [BR:
mtu01000
]
1. Oxidoreductases
1.4 Acting on the CH-NH2 group of donors
1.4.1 With NAD+ or NADP+ as acceptor
1.4.1.2 glutamate dehydrogenase
Rv2476c (gdh)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Bac_GDH_CD
GDH_C
GDH_HM3
GDH_ACT2
GDH_ACT3
GDH_ACT1
GDH_HM1
GDH_HM2
Motif
Other DBs
NCBI-GeneID:
887437
NCBI-ProteinID:
NP_216992
TubercuList:
Rv2476c
UniProt:
O53203
LinkDB
All DBs
Position
complement(2777388..2782262)
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AA seq
1624 aa
AA seq
DB search
MTIDPGAKQDVEAWTTFTASADIPDWISKAYIDSYRGPRDDSSEATKAAEASWLPASLLT
PAMLGAHYRLGRHRAAGESCVAVYRADDPAGFGPALQVVAEHGGMLMDSVTVLLHRLGIA
YAAILTPVFDVHRSPTGELLRIEPKAEGTSPHLGEAWMHVALSPAVDHKGLAEVERLLPK
VLADVQRVATDATALIATLSELAGEVESNAGGRFSAPDRQDVGELLRWLGDGNFLLLGYQ
RCRVADGMVYGEGSSGMGVLRGRTGSRPRLTDDDKLLVLAQARVGSYLRYGAYPYAIAVR
EYVDGSVVEHRFVGLFSVAAMNADVLEIPTISRRVREALAMAESDPSHPGQLLLDVIQTV
PRPELFTLSAQRLLTMARAVVDLGSQRQALLFLRADRLQYFVSCLVYMPRDRYTTAVRMQ
FEDILVREFGGTRLEFTARVSESPWALMHFMVRLPEVGVAGEGAAAPPVDVSEANRIRIQ
GLLTEAARTWADRLIGAAAAAGSVGQADAMHYAAAFSEAYKQAVTPADAIGDIAVITELT
DDSVKLVFSERDEQGVAQLTWFLGGRTASLSQLLPMLQSMGVVVLEERPFSVTRPDGLPV
WIYQFKISPHPTIPLAPTVAERAATAHRFAEAVTAIWHGRVEIDRFNELVMRAGLTWQQV
VLLRAYAKYLRQAGFPYSQSYIESVLNEHPATVRSLVDLFEALFVPVPSGSASNRDAQAA
AAAVAADIDALVSLDTDRILRAFASLVQATLRTNYFVTRQGSARCRDVLALKLNAQLIDE
LPLPRPRYEIFVYSPRVEGVHLRFGPVARGGLRWSDRRDDFRTEILGLVKAQAVKNAVIV
PVGAKGGFVVKRPPLPTGDPAADRDATRAEGVACYQLFISGLLDVTDNVDHATASVNPPP
EVVRRDGDDAYLVVAADKGTATFSDIANDVAKSYGFWLGDAFASGGSVGYDHKAMGITAR
GAWEAVKRHFREIGIDTQTQDFTVVGIGDMSGDVFGNGMLLSKHIRLIAAFDHRHIFLDP
NPDAAVSWAERRRMFELPRSSWSDYDRSLISEGGGVYSREQKAIPLSAQVRAVLGIDGSV
DGGAAEMAPPNLIRAILRAPVDLLFNGGIGTYIKAESESDADVGDRANDPVRVNANQVRA
KVIGEGGNLGVTALGRVEFDLSGGRINTDALDNSAGVDCSDHEVNIKILIDSLVSAGTVK
ADERTQLLESMTDEVAQLVLADNEDQNDLMGTSRANAASLLPVHAMQIKYLVAERGVNRE
LEALPSEKEIARRSEAGIGLTSPELATLMAHVKLGLKEEVLATELPDQDVFASRLPRYFP
TALRERFTPEIRSHQLRREIVTTMLINDLVDTAGITYAFRIAEDVGVTPIDAVRTYVATD
AIFGVGHIWRRIRAANLPIALSDRLTLDTRRLIDRAGRWLLNYRPQPLAVGAEINRFAAM
VKALTPRMSEWLRGDDKAIVEKTAAEFASQGVPEDLAYRVSTGLYRYSLLDIIDIADIAD
IDAAEVADTYFALMDRLGTDGLLTAVSQLPRHDRWHSLARLAIRDDIYGALRSLCFDVLA
VGEPGESSEQKIAEWEHLSASRVARARRTLDDIRASGQKDLATLSVAARQIRRMTRTSGR
GISG
NT seq
4875 nt
NT seq
+upstream
nt +downstream
nt
atgacgatcgatcccggggctaagcaggatgttgaggcgtggaccacgttcaccgcgagt
gcggacattcctgactggatctcgaaggcctacatcgacagctatcgaggaccgcgcgac
gactcgtcggaagccaccaaggccgccgaggccagttggcttccagcctccctgctgacg
cccgccatgctgggcgcacattatcggcttggccggcaccgcgcggccggtgaaagctgt
gtcgccgtctatcgggcggacgatcccgcggggttcggtccggcgctgcaggtggtcgcc
gagcacggcggcatgctgatggattccgttacggtgctgctgcaccggcttggaatcgcc
tacgcggcgattctgaccccggtgttcgacgtgcaccgcagccccacgggagagctgctg
cgcatcgaaccgaaggccgagggcacgtcgccgcacctgggtgaggcctggatgcacgta
gcgctctcgcccgccgttgatcacaaaggcctcgccgaggtggagcggttgctgcccaag
gtgctggccgacgtccagcgggtggccaccgacgccacagcgctgatcgccaccctgagc
gagctggcgggagaagtcgaatccaatgccggcggccgattttccgcgcccgaccgacaa
gacgtcggggaactgttgcgttggctgggtgacgggaacttcctgctgctgggctaccaa
cggtgccgggtggctgacgggatggtctacggcgaggggtcaagcggtatgggcgtcctg
cggggccgcaccggttcgcgtccccggctgaccgacgacgacaaactgctggtgttggcc
caagcgcgggtcggcagctacctgcgttacggcgcctatccctatgccatcgcggtccgc
gaatacgtcgacggcagcgtggtcgagcaccgcttcgtcgggctcttcagcgtcgcggcc
atgaatgcggacgtgctggagatcccgacgatctcgcgccgggtccgcgaggcgctggcg
atggccgaaagcgatcccagccacccaggccaattgctgctcgacgtcatccagaccgtc
ccgcgaccggagctgttcaccctgagcgcgcagcgcctgctgaccatggccagggccgtg
gtggacttgggatcgcaacggcaggcgttgttgttcctgcgcgcggatcggttgcagtac
ttcgtgtcgtgcctggtctacatgccccgagatcgctacaccaccgccgtgcgcatgcaa
ttcgaggacatccttgtccgcgagttcgggggaacacgactggagttcaccgctcgggtc
agtgaatcaccttgggcactcatgcatttcatggtgcggctacccgaagtgggtgtggca
ggagaaggggcggccgccccgccggtggacgtttccgaagccaaccggatccggatccag
ggtctgctgaccgaagccgcgcgaacctgggccgaccgtttgatcggcgcggcggcggcg
gctggctccgtcggacaggccgacgctatgcattacgctgccgccttctccgaggcctac
aaacaggccgtcaccccggccgatgccattggcgacattgcggtcatcacggagctgacc
gacgattcggtcaagctggtgttttccgaacgcgacgagcagggtgtcgcccagttgacc
tggttcctcggtgggcgcaccgcttcgctgagccagctgctgccgatgctgcaaagcatg
ggagtcgtggtgctcgaagagcgaccgttctccgtcacccggccggacggtctgccggtc
tggatctatcagttcaagatctcgccgcatcccacgatcccgttggccccgacggttgcc
gagcgggccgcgaccgcgcaccgattcgccgaggcggtgaccgcgatctggcacggccgg
gtcgaaatcgaccgattcaacgagctggtgatgcgtgccgggctgacttggcagcaggtc
gtgctgctccgtgcctacgcgaagtacctgcgccaggcgggcttcccgtacagccagtcc
tacattgaatcggtgctcaacgagcaccctgctaccgttcggtctttggtcgatctgttc
gaagcgcttttcgttccggtgccgtcggggtcggcgagcaatcgcgatgcccaagcggcc
gctgccgctgtcgccgcggacatcgacgcgctggtgagcctggacaccgaccggatcctg
cgcgccttcgcgtcgttggttcaggccacgttgcgcaccaattactttgtgacacgccag
ggttcggcccgctgccgtgatgtattggcgctgaaactcaatgcccagttgatcgacgaa
cttccgctgccgcgtccccggtacgagatttttgtgtattcgccccgcgtcgaaggcgtg
catctgaggttcggcccagttgcgcgtggcgggttgcgctggtcggaccgccgtgacgat
ttccgaaccgagattctcggattggtcaaggcgcaagcggtgaagaacgccgtcatcgtg
ccggtcggggccaagggcgggttcgtggtcaagcgtcccccgctgcccaccggcgacccc
gccgccgaccgcgacgccacccgcgccgaaggggtcgcctgctatcagctgttcatctcc
gggttgctcgatgtcaccgacaacgtcgatcatgcgaccgcaagcgtcaaccccccgccc
gaggtggtgcgacgtgacggcgacgacgcctacttggtagtggccgccgacaaaggtact
gccaccttttccgatatcgccaacgatgtcgccaagtcctatgggttctggctgggcgac
gcgttcgcctcgggcggatcggtgggctacgaccacaaggccatgggcatcaccgcccgg
ggggcctgggaggccgtaaaacggcatttccgagagatcgggatcgacacccagacccag
gatttcaccgtcgtgggaatcggcgacatgagcggcgacgtattcggcaacggcatgttg
ctgagcaagcacatccggctgatcgccgccttcgaccaccgccacatcttcctcgacccc
aaccccgatgccgcggtgtcgtgggccgaacgccggcggatgttcgagttgccccggtcc
agctggagcgactatgacaggtctctgatcagcgagggcggcggggtgtacagccgcgaa
cagaaagccatcccgctcagcgcgcaggtccgcgccgtcctcggcatcgacggctcagtt
gacgggggggccgccgagatggccccgcccaaccttattcgggcgattctgcgggcgccg
gtggacctgctgttcaacggcggcatcggcacttacatcaaggccgagtcagagtcggat
gctgatgtcggcgatcgcgccaacgatccggtgcgagtcaacgcgaatcaagtgcgcgcc
aaggtcattggcgaaggtggcaatctcggagtgacggcgttgggccgtgtcgaattcgat
ctgtccggcggccggatcaacaccgacgcgctggacaactccgccggcgtggactgctcg
gaccacgaggtcaacatcaagatcctgatcgactcgctggtgagcgccggcacggtcaaa
gccgacgaacgcacacagctgctcgagtcaatgaccgacgaggtagcgcaactggtgctc
gccgacaacgaagatcagaacgacttgatgggcaccagtcgcgccaacgcggccagcctg
ctgccggtgcacgcaatgcagatcaagtatttggtggctgagcgcggggtcaaccgcgaa
ttggaagcgctgccgtcggagaaggagattgcccggcgctccgaggccggcatcgggctc
acctcgcccgaactcgccacgctgatggcgcacgtcaagctggggctcaaagaggaggtg
ctagccaccgaactaccggatcaggatgtcttcgcttccaggttgcctcgttatttcccg
acggcgctgcgcgaacggttcaccccggagatccgttcccaccagctgcgccgcgagatc
gtcaccaccatgctgatcaacgatctggtggataccgccggcatcacctatgcgttccgg
atcgccgaagacgttggtgtcacgccgatcgatgccgtgcgcacctatgtcgccaccgat
gccatcttcggtgtcggtcacatttggcgccggatccgtgcggcgaacctgccaatcgcg
ctgtcagacaggttgacgctggacacccgtcggctgatcgaccgtgccggacgctggctg
ctcaactaccgtccgcagcccttggccgtcggcgccgagatcaaccgattcgcggccatg
gtcaaggcactgacaccgcgcatgtcggagtggttgcgtggtgatgacaaggccatcgtc
gaaaagacagctgcggaattcgcatcgcagggtgtgcctgaagacttggcctaccgtgtc
tcgaccggcctgtaccggtacagcctgctcgacatcatcgacatcgccgacatcgccgac
atcgacgccgccgaggtcgctgacacctatttcgccctgatggaccggctgggcaccgat
ggcctgctgaccgcggtatcccagctgccccgacacgaccgctggcattcgttggcgcgc
ttggcgattcgcgacgatatttacggtgcgctacggtcgttgtgtttcgacgtgctggcc
gtgggggaacccggcgagagtagcgagcaaaagatcgccgagtgggaacacctcagcgcc
tcccgggtggcgcgggcacgtcggacactcgacgacatccgtgccagcggccagaaggat
ctggcgacgttgtcggtcgccgcgcggcagatccgccgcatgacacggacaagcgggcga
ggaatctcggggtga
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