KEGG   Mycobacterium tuberculosis H37Rv: Rv2763c
Entry
Rv2763c           CDS       T00015                                 
Symbol
dfrA
Name
(RefSeq) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
mtu  Mycobacterium tuberculosis H37Rv
Pathway
mtu00670  One carbon pool by folate
mtu00790  Folate biosynthesis
mtu01100  Metabolic pathways
mtu01240  Biosynthesis of cofactors
mtu04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:mtu00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    Rv2763c (dfrA)
   00670 One carbon pool by folate
    Rv2763c (dfrA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    Rv2763c (dfrA)
Enzymes [BR:mtu01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     Rv2763c (dfrA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 887777
NCBI-ProteinID: NP_217279
TubercuList: Rv2763c
UniProt: P9WNX1
Structure
LinkDB
Position
complement(3073130..3073609)
AA seq 159 aa
MVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGR
RNVVLSRQADFMASGAEVVGSLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLP
REAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS
NT seq 480 nt   +upstreamnt  +downstreamnt
atggtggggctgatctgggctcaagcgacatcgggtgtcatcggccgcggcggcgacatc
ccctggcgcttgcccgaggaccaggcgcatttccgggagatcaccatggggcacacgatc
gtgatgggccggcgcacatgggattcgctgccggctaaagtccggccgctgcccggccgg
cgaaatgtcgtactgagccgccaagctgactttatggccagcggggctgaggttgtcggt
tcactcgaggaggcgctgaccagcccggagacgtgggtgatcggaggcggacaagtctat
gcgctggcgctgccgtacgcgaccagatgtgaggttaccgaggtcgacatcggcctgccg
cgcgaagccggtgacgcgctggcccccgtgctggacgagacatggcggggcgagacgggg
gagtggcgcttcagccggtccgggttgcggtaccggttgtacagctaccaccgctcatga

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