Mycobacterium tuberculosis Haarlem/NITR202: I917_15785
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Entry
I917_15785 CDS
T02654
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase subunit E1
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mtuh
Mycobacterium tuberculosis Haarlem/NITR202
Pathway
mtuh00010
Glycolysis / Gluconeogenesis
mtuh00020
Citrate cycle (TCA cycle)
mtuh00620
Pyruvate metabolism
mtuh00785
Lipoic acid metabolism
mtuh01100
Metabolic pathways
mtuh01110
Biosynthesis of secondary metabolites
mtuh01120
Microbial metabolism in diverse environments
mtuh01200
Carbon metabolism
mtuh01210
2-Oxocarboxylic acid metabolism
Module
mtuh_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mtuh00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
I917_15785 (aceE)
00020 Citrate cycle (TCA cycle)
I917_15785 (aceE)
00620 Pyruvate metabolism
I917_15785 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
I917_15785 (aceE)
Enzymes [BR:
mtuh01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
I917_15785 (aceE)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AGL23860
UniProt:
R4LZF6
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All DBs
Position
2512397..2515192
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AA seq
931 aa
AA seq
DB search
MTTDFARHDLAQNSNSASEPDRVRVIREGVASYLPDIDPEETSEWLESFDTLLQRCGPSR
ARYLMLRLXERXGXQRXXIPALTSTDYVNTIPTELEPWFPGDEDVERRYRAWIRWNAAIM
VHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKSHPGGGDQVFIQGHASPGIYARAF
LEGRLTAEQLDGFRQEHSHVGGGXPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHY
LHDRGIKDTSDQHVWCFLGDGEMDEPESRGLAHVGALEGLDNLTFVINCNLQRLDGPVRG
NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDGDYQTYKANDG
GYVRDHFFGRDPRTKALVENMSDQDIWNLKRGGHDYRKVYAAXRAAVDHKGQPTVILAKT
IKGYALGKHFEGRNATHQMKKLTLEDLKEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAP
EIRYMLDRRRALGGFVPERRTKSKALTLPGRDIYAPLKKGSGHQEVATTMATVRTFKEVL
RDKQIGPRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDADLMLAYKESEVGQILH
EGINEAGSVGSFIAAGTSYATHNGXXRSPFTSSTRCSASSAPAIASGPRPTRWLEGSCXX
ATAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFXYEIAYIVESGLARMCGENPENI
FFYITVYXEPYXQPPEPENFDPEGVLRGIYRYHAATEQRTNKAQILASGVAMPXALRAAQ
MLAAEWDVAADVWSVTSWGELNRDGVAIETEKLRHPDRPAGVPYVTRALENARGPVIAVS
DWMRAVPEQIRPWVPGTYLTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGDGEI
DPSVPVAAARQYRIDDVAAAPEQTTDPGPGA
NT seq
2796 nt
NT seq
+upstream
nt +downstream
nt
ttgaccaccgatttcgcccgccacgatctggcccaaaactcaaacagcgcaagcgaaccc
gaccgagttcgggtgatccgcgagggtgtggcgtcgtatttgcccgacattgatcccgag
gagacctcggagtggctggagtcctttgacacgctgctgcaacgctgcggcccgtcgcgg
gcccgctacctgatgttgcggctgstagagcgggscggsgrgcagcgggkggscatcccs
gcattgacgtctaccgactatgtcaacaccatcccgaccgagctggagccgtggttcccc
ggcgacgaagacgtcgaacgtcgttatcgagcgtggatcagatggaatgcggccatcatg
gtgcaccgtgcgcaacgaccgggtgtgggcgtgggtggccatatctcgacctacgcgtcg
tccgcggcgctctatgaggtcggtttcaaccacttcttccgcggcaagtcgcacccgggc
ggcggcgatcaggtgttcatccagggccacgcttccccgggaatctacgcgcgcgccttc
ctcgaagggcggttgaccgccgagcaactcgacggattccgccaggaacacagccatgtc
ggcggcgggktgccgtcctatccgcacccgcggctcatgcccgacttctgggaattcccc
accgtgtcgatgggtttgggcccgctcaacgccatctaccaggcacggttcaaccactat
ctgcatgaccgcggtatcaaagacacctccgatcaacacgtgtggtgttttttgggcgac
ggcgagatggacgaacccgagagccgtgggctggcccacgtcggcgcgctggaaggcttg
gacaacttgaccttcgtgatcaactgcaatctgcagcgactcgacggcccggtgcgcggc
aacggcaagatcatccaggagctggagtcgttcttccgcggtgccggctggaacgtcatc
aaggtggtgtggggccgcgaatgggatgccctgctgcacgccgaccgcgacggtgcgctg
gtgaatttaatgaatacaacacccgatggcgattaccagacctataaggccaacgacggc
ggctacgtgcgtgaccacttcttcggccgcgacccacgcaccaaggcgctggtggagaac
atgagcgaccaggatatctggaacctcaaacggggcggccacgattaccgcaaggtttac
gccgcctmccgcgccgccgtcgaccacaagggacagccgacggtgatcctggccaagacc
atcaaaggctacgcgctgggcaagcatttcgaaggacgcaatgccacccaccagatgaaa
aaactgaccctggaagaccttaaggagtttcgtgacacgcagcggattccggtcagcgac
gcccagcttgaagagaatccgtacctgccgccctactaccaccccggcctcaacgccccg
gagattcgttacatgctcgaccggcgccgggccctcgggggctttgttcccgagcgcagg
accaagtccaaagcgctgaccctgccgggtcgcgacatctacgcgccgctgaaaaagggc
tctgggcaccaggaggtggccaccaccatggcgacggtgcgcacgttcaaagaagtgttg
cgcgacaagcagatcgggccgcggatagtcccgatcattcccgacgaggcccgcaccttc
gggatggactcctggttcccgtcgctaaagatctataaccgcaatggccagctgtatacc
gcggttgacgccgacctgatgctggcctacaaggagagcgaagtcgggcagatcctgcac
gagggcatcaacgaagccgggtcggtgggctcgttcatcgcggccggcacctcgtatgcg
acgcacaacggarccgakcgatccccatttacatcttctactcgatgttcggcttccagc
gcaccggcgatagcttctgggccgcggccgaccagatggctcgagggttcgtgcycrgra
gccaccgccgggcgcaccaccctgaccggtgagggcctgcaacacgccgacggtcactcg
ttgctgctggccgccaccaacccggcggtggttgcctacgacccggccttcrcctacgaa
atcgcctacatcgtggaaagcggactggccaggatgtgcggggagaacccggagaacatc
ttcttctacatcaccgtctacarcgagccgtacrtgcagccgccggagccggagaacttc
gatcccgagggcgtgctgcggggtatctaccgctatcacgcggccaccgagcaacgcacc
aacaaggcgcagatcctggcctccggggtagcgatgcccrcggcgctgcgggcagcacag
atgctggccgccgagtgggatgtcgccgccgacgtgtggtcggtgaccagttggggcgag
ctaaaccgcgacggggtggccatcgagaccgagaagctccgccaccccgatcggccggcg
ggcgtgccctacgtgacgagagcgctggagaatgctcggggcccggtgatcgcggtgtcg
gactggatgcgcgcggtccccgagcagatccgaccgtgggtgccgggcacatacctcacg
ttgggcaccgacgggttcggcttttccgacactcggcccgccgctcgccgctacttcaac
accgacgccgaatcccaggtggtcgcggttttggaggcgttggcgggcgacggcgagatc
gacccatcggtgccggtcgcggccgcccgccagtaccggatcgacgacgtggcggctgcg
cccgagcagaccacggatcccggtcccggggcctaa
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