KEGG   Mycobacterium tuberculosis Haarlem/NITR202: I917_19365
Entry
I917_19365        CDS       T02654                                 
Name
(GenBank) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
mtuh  Mycobacterium tuberculosis Haarlem/NITR202
Pathway
mtuh00670  One carbon pool by folate
mtuh00790  Folate biosynthesis
mtuh01100  Metabolic pathways
mtuh01240  Biosynthesis of cofactors
mtuh04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:mtuh00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    I917_19365
   00670 One carbon pool by folate
    I917_19365
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    I917_19365
Enzymes [BR:mtuh01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     I917_19365
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: AGL24342
UniProt: R4MA15
LinkDB
Position
complement(3068892..3069428)
AA seq 178 aa
MKSARTAFKPESRSDACDDGGAEIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIV
MGRRTWDSLPAKVRPLPGRRNVVLSRQADFMASGAEVVGSLEEALTSPETWVIGGXXVYA
LALPYATRCEVTEVDIGLPXEAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS
NT seq 537 nt   +upstreamnt  +downstreamnt
atgaagtcggctcggacagccttcaagccggaatcaaggagtgacgcgtgtgacgatggt
ggggctgagatctgggctcaagcgacatcgggtgtcatcggccgcggcggcgacatcccc
tggcgcttgcccgaggaccaggcgcatttccgggagatcaccatggggcacacgatcgtg
atgggccggcgcacatgggattcgctgccggctaaagtccggccgctgcccggccggcga
aatgtcgtactgagccgccaagctgactttatggccagcggggctgaggttgtcggttca
ctcgaggaggcgctgaccagcccggagacgtgggtgatcggaggcgramaagtctatgcg
ctggcgctgccgtacgcgaccagatgtgaggttaccgaggtcgacatcggcctgccgsgc
gaagccggtgacgcgctggcccccgtgctggacgagacatggcggggcgagacgggggag
tggcgcttcagccggtccgggttgcggtaccggttgtacagctaccaccgctcatga

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