Mycobacterium tuberculosis Haarlem: TBHG_00102 Help Entry TBHG_00102        CDS       T02845                                  Name (GenBank) peptide synthetase Nrp   KO K28320   isonitrile lipopeptide synthase [EC:2.3.1.329] Organism mtul  Mycobacterium tuberculosis Haarlem Brite KEGG Orthology (KO) [BR:mtul00001]  09180 Brite Hierarchies   09181 Protein families: metabolism    01008 Polyketide biosynthesis proteins [BR:mtul01008]     TBHG_00102 Enzymes [BR:mtul01000]  2. Transferases   2.3  Acyltransferases    2.3.1  Transferring groups other than aminoacyl groups     2.3.1.329  isonitrile lipopeptide synthase      TBHG_00102 Polyketide biosynthesis proteins [BR:mtul01008]  Nonribosomal peptide synthetase (NRPS)   Nonlinear NRPS    Isonitrile lipopeptide synthase     TBHG_00102 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AMP-binding Condensation NAD_binding_4 PP-binding AMP-binding_C Epimerase 3Beta_HSD GH3 Polysacc_synt_2 Motif Other DBs NCBI-ProteinID:  EBA44114 LinkDB All DBs Position 110137..117675 Genome browser AA seq 2512 aa AA seqDB search MHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL NT seq 7539 nt NT seq  +upstreamnt  +downstreamnt gtgcaccgagttcggttaagccgctcgcagcgcaacctctacaacggcgtgcgccaggat aacaatcccgcgttatatctgatcggcaagagctatcggttccgccggttggagctggcg agattcctggccgctctgcacgcaacggtactggacaaccccgtgcaactttgcgtcctg gagaattcgggggcagactatccggatctggtgccgcggctacggttcggcgacatcgtg cgggtggggtcagccgatgagcacctgcagagcacatggtgttcgggcatcctgggcaag ccactggtgcggcatacggtgcacaccgacccgaacgggtatgtgaccggtctggacgtt cacacccaccacatcctgctggacggcggcgcgaccgggacgatcgaagctgacctggcg cgttacctgaccaccgacccggcgggcgaaacccccagtgtcggtgcgggtctagccaag ctcagggaggcgcaccgtcgtgagacggccaaggtggaagaatcgcgggggcgcctgtcg gctgtcgtgcagcgtgaactcgccgacgaagcataccacggcgggcacgggcacagcgtt agcgacgctcccgggaccgcggccaagggcgtcctgcacgaatcggcaacgatctgcggc aacgcgtttgatgccatcctgaccctttcggaagcgcagcgggtcccgcttaatgtgctg gtggctgcggcggccgtcgcggtggacgcgagccttcggcagaacaccgaaaccctcttg gtgcacacggtggacaaccggttcggagattctgatctgaatgtcgcgacctgtttggtc aattcggttgcccagaccgtccggtttcccccatttgcgtcggtgtccgatgtcgttcga acgcttgaccgcggctatgtcaaggcggtaagacgccggtggcttcgtgaggagcattac cgccgaatgtatttggcgatcaaccggacatctcacgtggaggcgttgacgctaaatttc attcgcgagccatgcgcacctggcctgcgcccgttcttgtcggaggtcccgattgccacg gatatcggtccggtcgagggcatgacggtggcgtctgttctggacgaagaacagcgcaca ctgaacctagccatctggaaccgagccgatctgcccgcgtgcaagacacaccccaaggtc gcggaacggatagcggcagcgttggaatcgatggcggcgatgtgggatcggccgatcgcc atgatcgtcaacgactggttcgggatcggcccggacgggactcgctgccaaggcgattgg ccagcccgtcagccgtcgacgcccgcgtggtttctcgattccgcaaggggcgtccaccaa tttctcggcaggcgccgcttcgtctacccgtgggtcgcgtggttggtgcaacgcggcgcc gcaccgggtgatgttctggtgttcaccgacgacgacaccgacaagaccattgacctgctc atcgcgtgtcaccttgcgggttgcgggtacagcgtctgcgacaccgctgacgaaatttcc gtgcggaccaatgcgattaccgagcacggcgatggcatcttggtgacagtggtcgacgtg gccgccacccagctggcggttgtcggccatgacgagctgcggaaggtcgttgacgagcgc gtcacacaggtgacacacgacgcactgctggccaccaagaccgcctacatcatgccgacc tcgggaactaccggacaacccaagctggtgcgaatctcacacggctcgctcgcggttttc tgtgatgcgatcagccgcgcctacggttggggagcccacgacaccgttctgcagtgcgct ccgttgacatcggacatcagcgtcgaggagattttcggtggcgcggcctgtggcgcgcga ctggtgcgatccgcggctatgaaaaccggcgacctggcggcgctggttgacgatctcgtc gcccgcgagacgacaatcgtcgacctgccgaccgccgtctggcagctgttgtgcgccgac ggcgacgccattgacgcgatcggccgctcgcgcctgcggcagatcgtaatcggcggtgaa gccatccgctgtagcgccgtggacaagtggcttgaatcggctgcttcacaagggatctcg ctgctctcgagctatggtccaacagaagccacggtcgtcgccaccttcttgccgatcgtt tgcgaccagaccaccatggacggcgcactgctcaggctcggccggccgatcctaccgaac acggtgttcctcgcgttcggtgaagtcgtcattgtcggggatttagtcgccgacggctac ctcgggatcgacggcgacggcttcggcaccgtgacggccgcagacggttcccgacgccgt gcctttgccactggcgaccgggtgaccgtcgacgccgaaggatttccggtcttctccgga cgcaaagacgccgtcgtcaagatctccggcaagcgtgtcgatatcgctgaggtaaccagg cgcatcgccgaagaccccgcggtgtcagatgtcgccgtcgagttgcacagcggaagcctc ggagtgtggttcaagagccaacggacccgcgagggcgaacaagacgctgccgcggcgacc cggatcaggctcgtcctcgtgagtctgggagtgtcgtcgtttttcgttgtcggcgtgccg aatatcccgaggaagcccaacgggaagatcgacagcgacaacctgccgaggctgcctcag tggtcagctgctgggctaaacaccgccgagacgggtcagcgagcggccggcctctcgcag atctggagccggcagctcggccgggcaatcgggccggactcgtcgctgcttggtgagggc atcggctcgttggatctcatcagaatactgcccgagacgcgtaggtatctggggtggcgc ctctcgctgctggatctgatcggtgccgataccgccgccaatctggccgattacgcgcca acgcccgacgcgccgacgggcgaagatcggtttaggccgctggtggccgcgcaacggccc gcggcgattccgttgtcgtttgcccagcggcgactatggtttctcgaccagttacagcga cccgctccggtctacaacatggcggtggcgttgcggctgcgcgggtatctcgataccgag gcgttgggcgcggcggtcgccgatgtcgtgggccgccacgaaagcctacggacggtgttt ccggcggtcgacggggtccctcggcagctggtcatcgaagcgcggcgggcagatcttggc tgcgacatcgtcgatgccaccgcatggccggctgaccggctgcaacgggccatcgaggag gcggcgcgccacagcttcgatttggcaaccgagatacctttgcggacgtggcttttccgg atcgccgacgacgaacatgtgctggtggcggttgcacaccatatcgccgccgacggctgg tcggtggctccgctgacggccgatctgagtgcggcatatgccagccgttgtgcgggtcgg gcaccggactgggcgccattgccagtgcagtatgtcgattacacgctgtggcagcgggaa atcctcggtgatctcgacgacagcgacagcccgatcgccgcgcagctggcctactgggaa aatgcgttggccggtatgccggaacggctgcggctgcccaccgctcggccctatccaccg gttgccgatcagcgcggcgccagtttggtggtggattggccggcgtcggtgcaacagcag gtgcgtcggatcgcccgccagcacaacgcgaccagcttcatggtggtagctgccgggctt gccgtgctgctgtcgaaactcagcggaagccccgatgtggcggtcggatttcccatcgcc ggccgcagcgatcctgcgctggataacttggtgggcttttttgtcaacaccttggtgttg cgggtcaacctggccggtgatcccagcttcgccgaactgctggggcaggtgcgagcgcgc agcctggccgcctacgaaaatcaagacgtacctttcgaggtgctcgttgatcgcctcaaa cccactcgagccctgacccatcacccgctgatccaggtgatgttggcctggcaggacaat ccggttggacagctgaatttgggtgatctgcaggccaccccgatgccgatcgacacccgc accgcccgcatggacttggtgttttcgttagcggaacgcttcagcgagggtagcgaacct gccgggatcggcggagcggtggaataccgcaccgatgtgtttgaagcccaagcaatcgac gtgcttatcgagcggttgcggaaggtgttggtggcggtggccgctgctccggaacggacg gtgtcgtcgatcgatgcgctggatgggaccgagcgtgcccggttggatgagtggggtaac cgcgctgtgctgactgcgcccgcgcccacgccggtgtcgatcccgcagatgttggccgcc caggtggcacgtatccccgaagcggaggcggtgtgttgcggggacgcgtcgatgacgtat cgggaactcgacgaggcgtccaaccggttagcgcatcggctggcaggttgtggggccggc ccgggcgagtgtgtggcgctgctgttcgagcggtgcgcgccggcggtcgtggcgatggtg gcagtgctcaaaaccggggcggcgtatctgccgatcgatccggcgaatcctccgccgcgg gtggcgttcatgctcggcgacgcggtgcccgtggccgcggtcaccacggctgggctgcgc tcccggttggcgggacacgacttgccgatcatcgatgtcgtcgatgctttagcggcatat ccgggcacgcccccacccatgccggccgcagtgaacctcgcctacatcctgtacacctcg ggcactaccggcgagcccaaaggcgtggggatcacccatcgcaacgtcaccaggctgttc gcatcactgccggcacgcttgtcggcggcgcaggtgtggtcgcagtgtcattcctatggc ttcgacgcctcggcgtgggagatctggggcgcgttgctaggtggtgggcgactggtgatc gtgcccgagtcggtggcggcctcgccgaacgactttcatgggctgctcgtggccgaacac gtcagcgtgctgactcagactccggctgcggtggcaatgttgccgacgcagggtttggag tcggtggcgttggtggtggccggtgaggcatgtccggcagcgctggtggatcggtgggcg cccgggcgggtgatgctaaatgcttatggcccaaccgagaccacgatctgtgcggcgata agtgcgccgttgcgaccgggttcggggatgccgccgattggtgttccggtgtcgggggcg gcgttgtttgtgctggatagctggttgcgcccggtaccggccggggtggccggagagttg tacattgccggtgcgggcgtcggtgttgggtattggcgtcgggcggggctgaccgcgtca cggtttgtggcctgcccattcggcggttccggggcacgcatgtatcgcaccggggatctg gtgtgttggcgcgccgatggccagttggagttcctggggcgcaccgacgatcaggtcaag atccgcgggtatcgcatcgagctcggcgaggttgcgaccgcgctggccgagctggctggg gtaggtcaagcggttgtaatcgcccgtgaagaccgccctggggacaagcgcctagtcggg tatgccaccgaaattgcccccggggcagtggacccggccgggctgcgggcgcaactagcc cagcgattgcccggttacctggtgccagccgcggtggtagtgatcgatgcgcttccgttg acggtcaacggcaaacttgatcatcgtgcgttgccggcaccggaatacggtgataccaac ggatatcgcgctccggccgggccggttgagaagaccgtggccggcatctttgcccgggtg cttgggcttgagcgggtcggcgtcgacgactcgttcttcgagctcggcggcgattcgctg gcggcaatgcgggttatcgccgcgatcaacaccaccctaaacgccgatctgccggtgcgc gcgttgctgcacgcgtcgtcgacgagaggtttaagccagctgttggggcgagatgcccga ccgaccagcgatccgcgcttggtgtctgtgcacggcgacaaccccaccgaggtgcatgcc agcgacctcacgctggaccggttcatcgacgccgacacgctggccaccgccgtcaacctg ccgggcccgagccccgagctacggacggtcctgctgacgggcgcgacgggtttcctcgga cggtatctggtccttgaattgctgcggcggctggacgtcgacggcaggctgatctgtttg gtgcgggcggagtccgacgaggatgcgcggcgtcgtctggagaagaccttcgatagcggt gacccggaattgctgcggcacttcaaggagcttgccgccgaccggctggaggtcgtcgca ggcgacaagagcgaacccgacctgggcctggaccaaccgatgtggcggcggctggccgaa accgtggatttgattgtcgattccgcggcgatggtcaacgcgtttccctaccacgaattg ttcgggcccaacgtcgcgggcaccgccgagctgatccgaatcgcgcttaccaccaagctc aaacccttcacctacgtgtcaaccgccgacgtgggtgctgcgatcgagccgtcggcgttc accgaggacgccgacatccgggtaatcagccccacccgcaccgtcgacggcggctgggct ggcggctacggcaccagcaagtgggccggtgaggtgctgctgcgcgaggccaacgacctg tgcgcgctgccggtcgcggtgtttcgctgcgggatgatcctggccgacaccagctatgcc ggacagctcaacatgtcggactgggtcacccggatggtgttgagcttgatggctaccggc atcgcgcctcgttcgttctacgaaccggactccgagggcaatcggcaacgcgcgcacttc gacgggctgccagtcaccttcgttgccgaggcgatcgcggtgctgggcgcgcgggtggcc ggctcatcgttggcgggatttgcgacctatcacgtgatgaacccgcacgacgacggtatc gggctcgatgagtatgtggactggctgattgaggccggctacccgatacgccgcatcgat gactttgcggagtggttgcagcggtttgaggccagcctgggcgctctgccggatcggcaa cgccggcactcggtgctgccgatgctgctggcgagcaattcccagcgattgcagccgctt aagccgaccagggggtgctccgcgccgaccgaccgattccgtgccgcggtgcgagcggcg aaagtcggctccgacaaggacaatccagacatcccgcacgtgtcggcgccgaccatcatc aactacgtcaccaacctacaactgctcggactgctgtag

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