KEGG   Mycobacterium tuberculosis Haarlem: TBHG_02946
Entry
TBHG_02946        CDS       T02845                                 
Name
(GenBank) DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
mtul  Mycobacterium tuberculosis Haarlem
Pathway
mtul03030  DNA replication
mtul03410  Base excision repair
mtul03420  Nucleotide excision repair
mtul03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:mtul00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    TBHG_02946
   03410 Base excision repair
    TBHG_02946
   03420 Nucleotide excision repair
    TBHG_02946
   03430 Mismatch repair
    TBHG_02946
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:mtul03032]
    TBHG_02946
   03400 DNA repair and recombination proteins [BR:mtul03400]
    TBHG_02946
Enzymes [BR:mtul01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     TBHG_02946
DNA replication proteins [BR:mtul03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     TBHG_02946
DNA repair and recombination proteins [BR:mtul03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     TBHG_02946
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     TBHG_02946
   MMR (mismatch excision repair)
    DNA ligase
     TBHG_02946
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      TBHG_02946
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD HHH_5 PTCB-BRCT Nlig-Ia HHH BRCT_2 Auto_anti-p27 DUF4796_N
Other DBs
NCBI-ProteinID: EBA43207
LinkDB
Position
complement(3368643..3370718)
AA seq 691 aa
MSSPDADQTAPEVLRQWQALAEEVREHQFRYYVRDAPIISDAEFDELLRRLEALEEQHPE
LRTPDSPTQLVGGAGFATDFEPVDHLERMLSLDNAFTADELAAWAGRIHAEVGDAAHYLC
ELKIDGVALSLVYREGRLTRASTRGDGRTGEDVTLNARTIADVPERLTPGDDYPVPEVLE
VRGEVFFRLDDFQALNASLVEEGKAPFANPRNSAAGSLRQKDPAVTARRRLRMICHGLGH
VEGFRPATLHQAYLALRAWGLPVSEHTTLATDLAGVRERIDYWGEHRHEVDHEIDGVVVK
VDEVALQRRLGSTSRAPRWAIAYKYPPEEAQTKLLDIRVNVGRTGRITPFAFMTPVKVAG
STVGQATLHNASEIKRKGVLIGDTVVIRKAGDVIPEVLGPVVELRDGSEREFIMPTTCPE
CGSPLAPEKEGDADIRCPNARGCPGQLRERVFHVASRNGLDIEVLGYEAGVALLQAKVIA
DEGELFALTERDLLRTDLFRTKAGELSANGKRLLVNLDKAKAAPLWRVLVALSIRHVGPT
AARALATEFGSLDAIAAASTDQLAAVEGVGPTIAAAVTEWFAVDWHREIVDKWRAAGVRM
VDERDESVPRTLAGLTIVVTGSLTGFSRDDAKEAIVARGGKAAGSVSKKTNYVVAGDSPG
SKYDKAVELGVPILDEDGFRRLLADGPASRT
NT seq 2076 nt   +upstreamnt  +downstreamnt
gtgagctccccagacgccgatcagaccgctcccgaggtgttgcggcagtggcaggcactg
gccgaggaggtgcgtgagcaccagttccgttattacgtgcgggacgcgccgatcatcagc
gacgcggaattcgacgagctgctgcgccgtctggaagccctcgaggagcagcatcccgag
ctgcgcacgcccgattcgccgacccagctggtcggcggtgccggcttcgccacggatttc
gagcccgtcgaccatctcgaacgaatgctcagcctcgacaacgcgttcaccgccgacgaa
ctcgccgcctgggccggccgcatccatgccgaggtcggagacgccgcacattacctgtgt
gagctcaagatcgacggcgtcgcgctgtctttggtctaccgcgagggacggctgacccgg
gcctccacccgcggcgacgggcgcaccggcgaggacgtcaccctgaacgcccggaccatc
gccgacgttcccgaacggctcacccccggcgacgactacccggtgcccgaggtcctcgag
gtccgcggcgaggtcttcttccggctggacgacttccaggcgctcaacgccagcctcgtc
gaggagggcaaggcgccgttcgccaacccccgcaacagcgcggcgggatcgctgcgccag
aaagacccggcggtcaccgcgcgccgccggctgcggatgatctgccacgggctgggccac
gtggagggctttcgcccggccaccctgcatcaggcatacctggcgttgcgggcatgggga
ctgccggtttccgaacacaccaccctggcaaccgacctggccggtgtgcgcgagcgcatc
gactactggggcgagcaccgccacgaggtggaccacgaaatcgacggcgtggtggtcaaa
gtcgacgaggtggcgttgcagcgcaggctgggttccacgtcgcgggcgccgcgctgggcc
atcgcctacaagtacccgcccgaggaagcgcagaccaagctgctcgacatccgggtgaac
gtcggccgcaccgggcggatcacgccgtttgcgttcatgacgccggtgaaggtggccggg
tcgacggtgggacaggccaccctgcacaacgcctcggagatcaagcgcaagggcgtgctg
atcggcgacaccgtggtgatccgcaaggccggcgacgtgatccccgaggtgctgggaccc
gtcgtcgaactgcgcgatggctccgaacgcgaattcatcatgcccaccacctgcccggag
tgcggttcgccgttggcgccggagaaggaaggcgacgccgacatccgttgccccaacgcc
cgcggctgcccggggcaactgcgggagcgggttttccacgtcgccagccgcaacggccta
gacatcgaggtgctcggttacgaggcgggtgtggcgctcttgcaggcgaaggtgatcgcc
gacgagggcgagctgttcgcgctgaccgagcgggacttgctgcgcaccgacctgttccga
accaaggcaggcgaactgtcggccaacggcaaacggctgctggtcaacctcgacaaggcc
aaggcggcaccgctgtggcgggtgctggtggcgctgtccatccgccatgtcgggccgacg
gcggcccgcgccctggccaccgagttcggcagccttgacgccatcgccgcggcgtccacc
gaccagctggccgccgtcgagggggtggggccgaccattgccgccgcggtcaccgagtgg
ttcgccgtcgactggcaccgcgagatcgtcgacaagtggcgggccgccggggtgcgaatg
gtcgacgagcgtgacgagagtgtgccacgcacgctggccgggctgaccatcgtggtcacc
ggctcgctgaccggtttctcccgcgacgacgccaaggaggcgatcgtggcccgcggcggc
aaggccgccggctcggtgtcgaagaagaccaactatgtcgtcgccggagactcgccggga
tccaaatacgacaaggcggtggagttgggggtgccgattctggacgaggatgggttccgg
agactgctggccgacggacccgcgtcacgaacgtaa

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