Mycobacterium tuberculosis BT1: HKBT1_2242
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Entry
HKBT1_2242 CDS
T03152
Symbol
metH
Name
(GenBank) 5-methyltetrahydrofolate-homocysteine methyltransferase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
mtut
Mycobacterium tuberculosis BT1
Pathway
mtut00270
Cysteine and methionine metabolism
mtut00450
Selenocompound metabolism
mtut00670
One carbon pool by folate
mtut01100
Metabolic pathways
mtut01110
Biosynthesis of secondary metabolites
mtut01230
Biosynthesis of amino acids
mtut04980
Cobalamin transport and metabolism
mtut04981
Folate transport and metabolism
Module
mtut_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
mtut00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
HKBT1_2242 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
HKBT1_2242 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
HKBT1_2242 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
HKBT1_2242 (metH)
04980 Cobalamin transport and metabolism
HKBT1_2242 (metH)
Enzymes [BR:
mtut01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
HKBT1_2242 (metH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pterin_bind
Met_synt_B12
B12-binding_2
S-methyl_trans
B12-binding
Na_Ca_ex_C
Motif
Other DBs
NCBI-ProteinID:
AHJ51188
LinkDB
All DBs
Position
complement(2379283..2382186)
Genome browser
AA seq
967 aa
AA seq
DB search
MIGLNCATGPAEMSEHLRHLSRHARIPVSVMPNAGLPVLGAKGAEYPLLPDELAEALAGF
IAEFGLSLVGGCCGTTPAHIREVAAAVANIKRPERQVSYEPSVSSLYTAIPFAQDASVLV
IGERTNANGSKGFREAMIAEDYQKCLDIAKDQTRDGAHLLDLCVDYVGRDGVADMKALAS
RLATSSTLPIMLDSTETAVLQAGLEHLGGRCAINSVNYEDGDGPESRFAKTMALVAEHGA
AVVALTIDEEGQARTAQKKVEIAERLINDITGNWGVDESSILIDTLTFTIATGQEESRRD
GIETIEAIRELKKRHPDVQTTLGLSNISFGLNPAARQVLNSVFLHECQEAGLDSAIVHAS
KILPMNRIPEEQRNVALDLVYDRRREDYDPLQELMRLFEGVSAASSKEDRLAELAGLPLF
ERLAQRIVDGERNGLDADLDEAMTQKPPLQIINEHLLAGMKTVGELFGSGQMQLPFVLQS
AEVMKAAVAYLEPHMERSDDDSGKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNIGI
KQPIATILEVAEDKSADVVGMSGLLVKSTVVMKENLEEMNTRGVAEKFPVLLGGAALTRS
YVENDLAEIYQGEVHYARDAFEGLKLMDTIMSAKRGEAPDENSPEAIKAREKEAERKARH
QRSKRIAAQRKAAEEPVEVPERSDVAADIEVPAPPFWGSRIVKGLAVADYTGLLDERALF
LGQWGLRGQRGGEGPSYEDLVETEGRPRLRYWLDRLSTDGILAHAAVVYGYFPAVSEGND
IVVLTEPKPDAPVRYRFHFPRQQRGRFLCIADFIRSRELAAERGEVDVLPFQLVTMGQPI
ADFANELFASNAYRDYLEVHGIGVQLTEALAEYWHRRIREELKFSGDRAMAAEDPEAKED
YFKLGYRGARFAFGYGACPDLEDRAKMMALLEPERIGVTLSEELQLHPEQSTDAFVLHHP
EAKYFNV
NT seq
2904 nt
NT seq
+upstream
nt +downstream
nt
atgatcggcttgaactgcgcgacgggtccggccgagatgagcgagcacctgcgccacctg
tcccggcacgcccgcatcccggtgtcggtgatgcccaacgccgggttgccggtgctgggc
gccaagggcgccgaatatccgttgctgcccgacgaattggccgaggcgctggccggcttc
atcgccgagttcgggctctcgctggtcggtggctgctgcggcaccaccccggcccatatc
cgcgaagtggctgccgcggttgcgaacatcaagcgtcccgagcgacaggtcagctacgag
ccgtcggtgtcgtcgctgtacaccgcaatcccgttcgcccaggacgcctcggttctggtg
atcggggagcgaacgaacgccaacggctccaagggttttcgtgaggcgatgatcgccgag
gactaccagaagtgcctggacatcgccaaggaccagacccgcgacggcgcccacctgctg
gacctgtgtgtggactacgtgggccgcgacggtgtggccgacatgaaggcgctggccagc
cggctggccacgtcctcgacgctgccgatcatgctggactccaccgaaaccgcggtgctg
caggcgggtttggagcatctgggtggccgttgcgcgatcaactcggtgaactacgaggac
ggcgacggcccggaatcgcgctttgccaagaccatggcgctggtcgccgagcacggcgcg
gcggtggtcgcgctgaccatcgacgaagagggccaggcccgcaccgcgcagaagaaggtc
gagatcgccgagcggctgatcaacgacatcaccggcaactggggcgtcgacgaatcatcc
atcctcatcgacaccttgacgttcaccatcgccaccggtcaggaggagtcccgccgcgac
ggcatcgagaccatcgaggcgatccgcgaactgaaaaagcgccacccggatgtgcagacc
acacttggtctgtccaacatctcgtttggtctcaatcccgcagcgcgccaggtgctcaac
tcggtgttcctgcacgaatgccaagaagcggggctggattcggcgatcgtgcacgcgtcg
aagatcctgccgatgaaccggattcccgaggagcaacgcaacgtcgccctggatctggtc
tacgaccgccgccgcgaggactacgatccgctgcaggagctgatgcggctgttcgaaggc
gtgtcggcggcctcctcgaaagaggaccgactggctgaactagctgggctgccgctgttc
gaacggctggcccaacgcatcgtcgacggcgagcgcaacggcctggacgccgatctcgac
gaggcgatgacgcaaaagccgccgcttcagatcatcaacgaacatctgctggccggcatg
aagacggtcggcgagctcttcggctccggccagatgcagctgccgttcgtgctgcagtcg
gcggaggtaatgaaagccgccgtcgcgtatctggaaccgcacatggagcgctcggacgac
gattcgggcaagggacgcatcgtgctggccaccgtcaagggcgacgtgcacgacatcggc
aagaacctggtcgacatcatcttgagcaacaacggctacgaagtggtcaacatcggcatc
aagcagccaatcgccaccatcctcgaagtcgccgaggacaagagcgccgacgtggtcggc
atgtcgggcctgctggtgaagtcgaccgtggtgatgaaggaaaacctcgaggagatgaac
acccggggagtcgccgaaaagttcccggtgctgctcggcggcgcggcgttgacgcgcagc
tatgtcgaaaacgacctggccgagatctaccagggcgaagtgcattacgcgcgagacgct
ttcgagggcctgaagttgatggacaccatcatgagcgccaagcgcggcgaggcgcccgac
gaaaacagcccggaagccattaaggcgcgtgagaaagaagccgaacgtaaggcccgccac
cagcgatccaaacgcattgccgcacagcgcaaagccgccgaagaaccagtcgaggtgccc
gaacgctccgatgtcgcggccgacatcgaggtcccggcgccgccgttctggggttcgcgg
atcgtcaagggcctggcggtggccgactacaccggtctgctcgatgagcgcgcattgttt
ttgggccagtggggtttacgcggccagcgcggcggtgagggtccgtcctacgaagatctc
gtcgagaccgagggccggccgcggctgcggtactggttggaccggctgtccaccgacggc
atcttggcgcacgccgccgtggtgtacggctatttcccggcggtgtccgagggcaacgac
atcgtggtgctcaccgagcccaagcccgacgccccggtgcgctaccggtttcacttcccg
cgccagcagcgcggtcggtttttgtgcattgccgatttcatccgctcgcgggagctggcc
gccgagcgtggcgaggttgacgtgctgccgttccagctggtgaccatgggtcagccgatc
gcggatttcgccaacgagctgttcgcgtccaacgcctaccgcgactacctggaggtgcac
ggtatcggcgtgcagctcaccgaggcgctggccgagtactggcaccggcggatccgtgag
gagctcaagttctccggggatcgggcgatggcggccgaggatccggaggcgaaagaagac
tatttcaagctcggctaccgcggtgctcgctttgccttcggctacggcgcatgcccggat
ctggaggaccgcgccaagatgatggcgctgctggagcccgaacgcatcggtgtgacgtta
tccgaggaattacagctgcatcccgaacagtcgaccgacgcgttcgtcctgcaccatccg
gaagccaagtacttcaacgtttaa
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