Mycobacterium tuberculosis BT2: HKBT2_2373
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Entry
HKBT2_2373 CDS
T03153
Symbol
accD6
Name
(GenBank) propionyl-CoA carboxylase subunit beta AccD6
KO
K18472
acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:
6.4.1.2
6.4.1.3
2.1.3.15
]
Organism
mtuu
Mycobacterium tuberculosis BT2
Pathway
mtuu00061
Fatty acid biosynthesis
mtuu00074
Mycolic acid biosynthesis
mtuu00280
Valine, leucine and isoleucine degradation
mtuu00620
Pyruvate metabolism
mtuu00630
Glyoxylate and dicarboxylate metabolism
mtuu00640
Propanoate metabolism
mtuu01100
Metabolic pathways
mtuu01110
Biosynthesis of secondary metabolites
mtuu01120
Microbial metabolism in diverse environments
mtuu01200
Carbon metabolism
mtuu01212
Fatty acid metabolism
Module
mtuu_M00082
Fatty acid biosynthesis, initiation
mtuu_M00741
Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA
mtuu_M00885
Meromycolic acid biosynthesis, initiation and elongation FAS II (KasA)
mtuu_M00886
Meromycolic acid biosynthesis, initiation and elongation FAS II (KasA and KasB)
Brite
KEGG Orthology (KO) [BR:
mtuu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
HKBT2_2373 (accD6)
00630 Glyoxylate and dicarboxylate metabolism
HKBT2_2373 (accD6)
00640 Propanoate metabolism
HKBT2_2373 (accD6)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
HKBT2_2373 (accD6)
00074 Mycolic acid biosynthesis
HKBT2_2373 (accD6)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
HKBT2_2373 (accD6)
Enzymes [BR:
mtuu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
HKBT2_2373 (accD6)
6. Ligases
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
HKBT2_2373 (accD6)
6.4.1.3 propionyl-CoA carboxylase
HKBT2_2373 (accD6)
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Gene cluster
GFIT
Motif
Pfam:
Carboxyl_trans
ACCA
MdcE
Motif
Other DBs
NCBI-ProteinID:
AHJ47170
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All DBs
Position
2505816..2507237
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AA seq
473 aa
AA seq
DB search
MTIMAPEAVGESLDPRDPLLRLSNFFDDGSVELLHERDRSGVLAAAGTVNGVRTIAFCTD
GTVMGGAMGVEGCTHIVNAYDTAIEDQSPIVGIWHSGGARLAEGVRALHAVGQVFEAMIR
ASGYIPQISVVVGFAAGGAAYGPALTDVVVMAPESRVFVTGPDVVRSVTGEDVDMASLGG
PETHHKKSGVCHIVADDELDAYDRGRRLVGLFCQQGHFDRSKAEAGDTGIHALLPESSRR
AYDVRPIVTAILDADTPFDEFQANWAPSMVVGLGRLSGRTVGVLANNPLRLGGCLNSESA
EKAARFVRLCDAFGIPLVVVVDVPGYLPGVDQEWGGVVRRGAKLLHAFGECTVPRVTLVT
RKTYGGAYIAMNSRSLNATKVFAWPDAEVAVMGAKAAVGILHKKKLAAAPEHEREALHDQ
LAAEHERIAGGVDSALDIGVVDEKIDPAHTRSKLTEALAQAPARRGRHKNIPL
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
atgacaatcatggcccccgaggcggttggcgagtcgctcgacccccgcgatccgctgttg
cggctgagcaacttcttcgacgacggcagcgtggaattgctgcacgagcgtgaccgctcc
ggagtgctggccgcggcgggcaccgtcaacggtgtgcgcaccatcgcgttctgcaccgac
ggcaccgtgatgggcggcgccatgggcgtcgaggggtgcacgcacatcgtcaacgcctac
gacactgccatcgaagaccagagtcccatcgtgggcatctggcattcgggtggtgcccgg
ctggctgaaggtgtgcgggcgctgcacgcggtaggccaggtgttcgaagccatgatccgc
gcgtccggctacatcccgcagatctcggtggtcgtcggtttcgccgccggcggcgccgcc
tacggaccggcgttgaccgacgtcgtcgtcatggcgccggaaagccgggtgttcgtcacc
gggcccgacgtggtgcgcagcgtcaccggcgaggacgtcgacatggcctcgctcggtggg
ccggagacccaccacaagaagtccggggtgtgccacatcgtcgccgacgacgaactcgac
gcctacgaccgtgggcgccggttggtcggattgttctgccagcaggggcatttcgatcgc
agcaaggccgaggccggtgacaccggcatccacgcgctgctgccggaatcctcgcgacgt
gcctacgacgtgcgtccgatcgtgacggcgatcctcgatgcggacacaccgttcgacgag
ttccaggccaattgggcgccgtcgatggtggtcgggctgggtcggctgtcgggtcgcacg
gtgggtgtactggccaacaacccgctacgcctgggcggctgcctgaactccgaaagcgca
gagaaggcagcgcgtttcgtgcggctgtgcgacgcgttcgggattccgctggtggtggtg
gtcgatgtgccgggctatctgcccggtgtcgaccaggagtggggtggcgtggtgcgccgt
ggcgccaagttgctgcacgcgttcggcgagtgcaccgttccgcgggtcacgctggtcacc
cgaaagacctacggcggggcatacattgcgatgaactcccggtcgttgaacgcgaccaag
gtgttcgcctggccggacgccgaggtcgcggtgatgggcgctaaggcggccgtcggcatc
ctgcacaagaagaagttggccgccgctccggagcacgaacgcgaagcgctgcacgaccag
ttggccgccgagcatgagcgcatcgccggcggggtcgacagtgcgctggacatcggtgtg
gtcgacgagaagatcgacccggcgcatactcgcagcaagctcaccgaggcgctggcgcag
gctccggcacggcgcggccgccacaagaacatcccgctgtag
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