Mycolicibacterium tokaiense: MTOK_56230
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Entry
MTOK_56230 CDS
T06987
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mty
Mycolicibacterium tokaiense
Pathway
mty00010
Glycolysis / Gluconeogenesis
mty00020
Citrate cycle (TCA cycle)
mty00620
Pyruvate metabolism
mty00785
Lipoic acid metabolism
mty01100
Metabolic pathways
mty01110
Biosynthesis of secondary metabolites
mty01120
Microbial metabolism in diverse environments
mty01200
Carbon metabolism
mty01210
2-Oxocarboxylic acid metabolism
Module
mty_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mty00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MTOK_56230 (aceE)
00020 Citrate cycle (TCA cycle)
MTOK_56230 (aceE)
00620 Pyruvate metabolism
MTOK_56230 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MTOK_56230 (aceE)
Enzymes [BR:
mty01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MTOK_56230 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
BBY89841
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Position
5799952..5802741
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AA seq
929 aa
AA seq
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MTTEFVRQDLAQNSGTAAEPDRVRVIREGVASYLPDIDPEETGEWLESFDDLVSRSGPAR
ARYLLLRMLERASEQRVSIPALTSTDYVNTIPTELEPWFPGDEDVERRYRAWIRWNAAIM
VHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKGHPGGGDQVFIQGHASPGVYARAF
LEGRLTADQMDGFRQEHSHPGGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHY
LHDRGIKDTSDQHVWAFLGDGEMDEAESRGLTHMAALEGLDNLTFVINCNLQRLDGPVRG
NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNSTPDGDYQTYKANDG
GYVRDHFFGRDPRTKSLVEPMTDAEIWNLKRGGHDYRKVYAAYRAAMEHKGQPTVILAKT
IKGYTLGKHFEGRNATHQMKKLALQDLKDFRDAQRIPVSDSQLEDNPYLPPYYHPGSDAP
EIRYMLDRRRALGGFLPERRTKSKPLTLPGRDAYKALKKGSGNQEVATTMATVRTFKELL
RDKNIGSRIVPIIPDEARTFGMDSWFPTLKIYNRNGQLYTAVDAELMLAYKESEVGQILH
EGINEAGSTASFTAVATSYSTHNEPMIPIYIFYSMFGFQRTGDGFWAAADQMARGFVLGA
TAGRTTLTGEGLQHADGHSLLLASTNPAVVAYDPAFAYEIAYIVEDGLRRMYGENPENIF
YYMTIYNEPYVQPKEPENFDPEGVLRGMYKFRAASEKRNSTAQILASGVAMPEALRAADM
LAEKWDVAADVWSVTSWGELNRDGVEVEKQKLRHPDRQAPESYVTKVLSDAVGPVVAVSD
WMRGVPELIRPWVPGTYLTLGADGFGFSDTRPAARRYFNTDAESVVVAVLEALARDGEID
PSVAVAAAKEYKIDDVLAAGVSFKDTGSA
NT seq
2790 nt
NT seq
+upstream
nt +downstream
nt
ttgacaaccgagttcgtgcgccaggacctggcccaaaactccggcaccgcagctgaacca
gatcgtgtacgtgtgatccgggaaggcgttgcctcgtatctgcccgacatcgaccccgaa
gagaccggtgagtggctggagtccttcgacgatctggtgtcgcggtccggaccggcccgg
gctcgttacctgctgctgcgaatgttggaacgcgccagcgagcagcgcgtctccatcccc
gcgctgacctccaccgattacgtcaacaccatccccaccgagctggagccgtggttcccc
ggcgacgaggacgtggagcgccgctaccgcgcctggatccgctggaacgccgccatcatg
gtgcaccgcgcgcagcggcccggcgtcggcgtcggcggccacatctccacctacgcgtcc
tcggcggcgctctacgaggtgggcttcaaccacttcttccgcggcaaaggccaccccggc
ggcggcgaccaggtgttcattcagggtcacgcctctcccggcgtctacgcccgcgccttc
ctcgagggccggctcaccgccgaccagatggacggcttccgtcaggagcacagccatccc
ggtggtgggctgccgtcctacccgcacccgcgcctgatgcccgacttctgggagttcccc
acggtgtcgatgggcctgggccccatgaatgccatctaccaggcgcggttcaaccattac
ctgcacgaccgcggcatcaaggacacctccgatcagcacgtgtgggcgttcctgggcgac
ggcgagatggacgaggcagagagccgcggcctgacccacatggccgccctcgagggcctg
gacaacctgacgttcgtcatcaactgcaacctgcagcgcctggatggcccggtgcgcggc
aacggcaagatcatccaggagctggagtcgttcttccgcggcgccggctggaacgtcatc
aaggtggtgtggggccgcgagtgggacgcgctgctgcacgccgaccgcgacggcgccctg
gtcaacctgatgaactccacccccgacggtgactaccagacctacaaggccaacgacggc
ggttacgtccgtgaccacttcttcgggcgcgacccgcgcaccaagtccctggtggaaccg
atgaccgacgcggagatctggaatctcaagcgcggcggccacgactaccgcaaggtgtac
gccgcctaccgcgcggccatggagcacaagggccagcccaccgtcatcctggccaagacc
atcaagggctacaccctgggcaagcacttcgagggccgcaacgccacgcaccagatgaaa
aagcttgcgctgcaagatctcaaggacttccgcgacgctcagcgcatcccggtctccgac
tcccagctcgaggacaacccgtacctgccgccgtactaccacccgggttcggacgcaccg
gagatccgctacatgctggaccgccggcgcgccctcggcgggttcctgcccgagcgtcgc
accaagtccaagccgctgacgctgccgggccgcgacgcgtacaaggcgttgaagaagggg
tcgggcaaccaggaggtcgccaccaccatggcgacggtgcgcacgttcaaggaactgctg
cgcgacaagaacatcggttcgcgaatcgtgccgatcatccccgacgaggctcggaccttc
gggatggactcgtggttcccgacgctgaagatctacaaccgcaacggccagctgtacacg
gctgtggacgccgagttgatgctggcgtacaaggaaagcgaagtcggtcagatcctgcac
gagggcatcaacgaggcggggtccacagcgtcgttcaccgcggtggccacctcgtattcc
acccacaacgagccgatgatcccgatctacatcttctattcgatgttcgggttccagcgc
accggtgacggcttctgggcggccgctgatcagatggcgcgcggtttcgtgctgggcgcc
acggccggccggaccacgctgaccggcgagggcctacagcacgccgacgggcattcgctg
ctgctggcgtccaccaacccggctgtggtggcctatgacccggcgttcgcctacgagatc
gcctacatcgtcgaagacgggctgcgccggatgtacggcgagaacccggagaacatcttc
tactacatgacgatctacaacgagccgtacgtccagcccaaggagccggagaacttcgac
cccgagggtgtattgcgcgggatgtacaagttccgggccgcgtcggagaagcgcaacagc
accgcgcagatcctggcctcgggcgtggccatgccggaggcgctgcgcgccgcggacatg
ctggccgagaagtgggacgtggccgccgatgtgtggtcggtgaccagctggggcgagctg
aaccgcgacggtgtcgaggtggagaagcagaagctgcgccaccccgatcgccaggccccg
gaaagctacgtgaccaaggtgctctccgatgccgtcggccccgtggtggcggtctcggac
tggatgcgcggcgtgccggaactgatccggccctgggtgcccggcacctacctcaccctg
ggggcggacgggttcggtttctccgacacccggcccgcggcgcggcggtatttcaacacc
gacgccgagtccgtggtggtggccgtgctggaggccctggcccgcgacggtgagatcgat
ccatccgtcgccgtggccgcggccaaggagtacaagatcgacgacgtgttggccgccggg
gtgtcgttcaaggacaccggcagcgcgtaa
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