KEGG   Mycobacterium ulcerans: MUL_1933
Entry
MUL_1933          CDS       T00435                                 
Symbol
ligA
Name
(GenBank) DNA ligase [NAD dependent] LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
mul  Mycobacterium ulcerans
Pathway
mul03030  DNA replication
mul03410  Base excision repair
mul03420  Nucleotide excision repair
mul03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:mul00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    MUL_1933 (ligA)
   03410 Base excision repair
    MUL_1933 (ligA)
   03420 Nucleotide excision repair
    MUL_1933 (ligA)
   03430 Mismatch repair
    MUL_1933 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:mul03032]
    MUL_1933 (ligA)
   03400 DNA repair and recombination proteins [BR:mul03400]
    MUL_1933 (ligA)
Enzymes [BR:mul01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     MUL_1933 (ligA)
DNA replication proteins [BR:mul03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     MUL_1933 (ligA)
DNA repair and recombination proteins [BR:mul03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     MUL_1933 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     MUL_1933 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     MUL_1933 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      MUL_1933 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden OB_DNA_ligase Nlig-Ia HHH_2 BRCT DNA_ligase_ZBD HHH_5 PTCB-BRCT HHH Auto_anti-p27 BRCT_2 DUF8259
Other DBs
NCBI-ProteinID: ABL04388
Pasteur: MUL_1933
UniProt: A0PPW9
LinkDB
Position
2137125..2139176
AA seq 683 aa
MLRQWQELAEQVREHQFRYYVRDAPVITDAEFDELLRRLEALEEQYPELRTPDSPTQLVG
GAGFATEFEPVEHLERMLSLDNAFNTEELTAWAGRIHADVGDSAAYLCELKIDGVALSLV
YEGGRLTRASTRGDGRTGEDVTLNARTIEDVPERLSHSEDHRMPEVLEVRGEVFFRVADF
QALNASLVEEGKAPFANPRNSAAGSLRQKDPAVTARRRLRMICHGLGHTEGFRPATLHQA
YLALQAWGLPVSQHTTLVADLAEVQARIDYWGEHRHEVDHEIDGVVVKVDDVALQRRLGS
TSRAPRWAIAYKYPPEEAQTKLLDIRVNVGRTGRVTPFAFMTPVKVAGSTVAQATLHNAS
EVKRKGVLIGDTVVIRKAGDVIPEVLGPVVDLRDGSEREFVMPTTCPECGTPLAPEKEGD
ADIRCPNTRSCPGQLRERVFHVSSRNALDIEMLGYEAGAALLSARVIGDEGDLFGLTEEE
LLRTDLFRTKAGDLSANGRRLLANLDKAKAAPLWRVLVALSIRHVGPTAARALATEFGSI
DAIVAATTEQLAAVEGVGPTIASAVSEWFTVDWHREIVERWRAAGVRMADERDDSVPRTL
AGVTVVVTGSLPGFSRDEAKEAIVTRGGKAAGSVSKKTSYVVAGDAPGSKYDKAVELGVP
ILDEDGFRKLLEQGPPAEAGEPT
NT seq 2052 nt   +upstreamnt  +downstreamnt
gtgttgcggcagtggcaggaactggccgagcaggtgcgtgaacaccagtttcgctactac
gtgcgcgacgcgccggtgatcaccgacgcggaattcgacgaattgctgcgccggctggag
gcgctcgaagaacagtatcccgagctacgcacacccgattcgcccactcagctggtcggt
ggcgccggtttcgcgaccgagttcgaacccgtcgagcatctggaaagaatgctcagcctc
gacaacgcgttcaacaccgaggaactcaccgcctgggccggccgcatccacgccgatgtc
ggcgacagtgcggcctatttgtgtgagctcaagattgacggcgtggcgctgtcgctggtg
tacgaaggggggcggctgacccgggcctccacccggggcgacggtcgcaccggcgaagat
gtcacgctcaatgcccgcaccatcgaggacgttccggaacggctttcccacagcgaggac
caccgcatgcccgaggtgctcgaggtccgcggtgaggtgttctttcgggtggctgatttc
caggcgctcaacgcgagcttggtcgaggagggcaaggcaccgttcgccaacccccgcaac
agcgcggccgggtcgttgcggcaaaaggacccggcggtcacggcccggcgcagattgcgg
atgatctgccatgggctgggccacaccgaaggctttcgcccggcgacgctgcaccaggcc
tacctggcgttgcaggcctgggggctgccggtttctcagcacaccacgctggtcgccgac
ctggccgaggtacaggcgcgcatcgactactggggcgagcatcgccacgaggtcgaccac
gaaatcgacggcgtggtggtcaaagtcgacgatgtcgccctgcagcggcggctcggttcc
acctcacgggcaccgcgctgggcgatcgcgtacaagtacccgcccgaggaagcccagacc
aagctgctcgatattcgggtcaacgtcggccgaaccgggcgagttacgccgtttgcgttc
atgacgccggtgaaggtcgcgggctcgacggtggcacaagccaccttgcacaacgcgtcg
gaggtcaagcgcaagggcgtgctgatcggcgacacggtggtgatccgcaaggccggtgac
gtgatccccgaagtgttgggtccggtggtcgacctccgtgatgggtccgaacgcgaattc
gtcatgcccacaacgtgtccggagtgcggcacgccgctggctccggagaaggagggcgac
gccgacatccgctgtccgaatacccgcagctgtccggggcagttgcgggagcgggttttt
catgtctccagccgcaatgccctcgacatcgagatgctgggctatgaggctggcgccgcg
ctgctttcggcgcgggtgatcggcgatgaaggcgacctgttcgggctcaccgaggaagag
ctgcttcgcaccgacctgttccgcaccaaggccggtgacttgtccgccaacggccggcgg
ctactggccaatctggacaaggcgaaggcggcgccactatggcgcgtgctggtggcgttg
tccatccgccatgtcggaccgacagcggcacgcgcactggccaccgagttcggcagcatc
gatgcgatcgtcgccgcgaccaccgaacagttggccgccgttgagggagtgggaccgacg
atcgcctccgccgtttcggagtggttcaccgtcgactggcaccgcgagatcgtcgagagg
tggcgggccgccggtgtgcggatggccgatgagcgcgacgacagtgtgccgcgcacactg
gccggggtaaccgtggtggtcaccggctcgttgcccggattctcacgggacgaggccaag
gaggcgatcgtgacccgtggcggcaaagccgccggttcggtatcgaaaaagacctcctac
gtcgtcgccggtgacgcacccggctcgaagtacgacaaggcggtcgaactcggcgtgccc
atcctcgacgaagatgggtttcgaaagttgttggagcagggccccccggccgaagcgggg
gagccgacctag

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