KEGG   Mycobacterium ulcerans: MUL_2179
Entry
MUL_2179          CDS       T00435                                 
Symbol
dfrA
Name
(GenBank) dihydrofolate reductase DfrA
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
mul  Mycobacterium ulcerans
Pathway
mul00670  One carbon pool by folate
mul00790  Folate biosynthesis
mul01100  Metabolic pathways
mul01240  Biosynthesis of cofactors
mul04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:mul00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    MUL_2179 (dfrA)
   00670 One carbon pool by folate
    MUL_2179 (dfrA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    MUL_2179 (dfrA)
Enzymes [BR:mul01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     MUL_2179 (dfrA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: ABL04587
Pasteur: MUL_2179
UniProt: A0PQG8
Structure
LinkDB
Position
2431756..2432253
AA seq 165 aa
MTSVGLIWAQSTSGVIGRDGGIPWRLPEDLAHFKRLTMGHTVVMGRRTWDSLPAAHRPLP
GRRNVVVTRQTGLVAHGAQVVGSLEQALCPAEPDAETWVIGGAQIYALALPLANRCEVTE
VDVDLPPEDEDALAPVLDQTWAGTSGEWLVSRSGLRYRMHSYRRL
NT seq 498 nt   +upstreamnt  +downstreamnt
atgacgtcggtgggcctgatctgggctcagtccacctccggggtcatcggccgtgatggc
ggcatcccgtggcgactgcccgaggatctcgcgcacttcaaacggctcaccatggggcac
accgtggtgatgggccgccggacctgggactccctgcccgccgcccaccggccactgcca
ggccggcgaaatgtcgtagtgacccgccagactggtctggtggcgcacggagcgcaggtg
gtgggttccctcgagcaggcgttgtgtccggccgagccggatgccgagacatgggtgatc
ggtggtgcccagatctacgcgctggcgctgcccctggcgaacaggtgtgaagtcaccgag
gtcgacgtcgacttaccgcccgaggacgaggacgccctggcccccgtgctcgaccagacc
tgggctggcacctcgggggagtggctggtcagccgctcgggactgcgataccggatgcac
agctaccgccgactatga

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