Meriones unguiculatus (Mongolian gerbil): 110547502
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Entry
110547502 CDS
T05884
Symbol
Irs1
Name
(RefSeq) insulin receptor substrate 1 isoform X1
KO
K16172
insulin receptor substrate 1
Organism
mun
Meriones unguiculatus (Mongolian gerbil)
Pathway
mun04022
cGMP-PKG signaling pathway
mun04068
FoxO signaling pathway
mun04081
Hormone signaling
mun04140
Autophagy - animal
mun04150
mTOR signaling pathway
mun04151
PI3K-Akt signaling pathway
mun04152
AMPK signaling pathway
mun04211
Longevity regulating pathway
mun04213
Longevity regulating pathway - multiple species
mun04722
Neurotrophin signaling pathway
mun04910
Insulin signaling pathway
mun04920
Adipocytokine signaling pathway
mun04923
Regulation of lipolysis in adipocytes
mun04930
Type II diabetes mellitus
mun04931
Insulin resistance
mun04932
Non-alcoholic fatty liver disease
mun04935
Growth hormone synthesis, secretion and action
mun04960
Aldosterone-regulated sodium reabsorption
mun05010
Alzheimer disease
mun05206
MicroRNAs in cancer
mun05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mun00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
110547502 (Irs1)
04022 cGMP-PKG signaling pathway
110547502 (Irs1)
04151 PI3K-Akt signaling pathway
110547502 (Irs1)
04152 AMPK signaling pathway
110547502 (Irs1)
04150 mTOR signaling pathway
110547502 (Irs1)
09133 Signaling molecules and interaction
04081 Hormone signaling
110547502 (Irs1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
110547502 (Irs1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
110547502 (Irs1)
04923 Regulation of lipolysis in adipocytes
110547502 (Irs1)
04920 Adipocytokine signaling pathway
110547502 (Irs1)
04935 Growth hormone synthesis, secretion and action
110547502 (Irs1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
110547502 (Irs1)
09156 Nervous system
04722 Neurotrophin signaling pathway
110547502 (Irs1)
09149 Aging
04211 Longevity regulating pathway
110547502 (Irs1)
04213 Longevity regulating pathway - multiple species
110547502 (Irs1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
110547502 (Irs1)
09164 Neurodegenerative disease
05010 Alzheimer disease
110547502 (Irs1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
110547502 (Irs1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
110547502 (Irs1)
04932 Non-alcoholic fatty liver disease
110547502 (Irs1)
04931 Insulin resistance
110547502 (Irs1)
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Motif
Pfam:
IRS
PH
PH_11
Motif
Other DBs
NCBI-GeneID:
110547502
NCBI-ProteinID:
XP_021490768
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Position
15:complement(68302387..68353106)
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AA seq
1233 aa
AA seq
DB search
MASPPDTDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHRSSAP
KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAAESEAEQDSWYQALLQLHNRAKAH
HDGAGGGGCGGSCSGSSGVGEAGEDLSYDTGPGPAFKEVWQVILKPKGLGQTKNLIGIYR
LCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQVDDSV
VAQNMHETILEAMRAMSDEFRPRSKSQSSSSCSNPISVPLRRHHLNNPPPSQVGLTRRSR
TESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHALRHRGSSR
LHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGG
FISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGASTLAAPNGHYI
LSRGGNGHRYLPGANLGISPALAGEEAAGAADLENRFRKRTHSAGTSPTITHQKTPSQSS
VASIEEYTEMMPVAYPPGGGSGGRLPGYRHSAFVPTHSYPEEGLEMHPLERRGGHHRLDT
SALHTDDGYMPMSPGVAPVPSNRKGNGDYMPMSPKSVSAPQQIINPIRRHPQRVDPNGYM
MMSPSGSCSPDVGGGSSSSGSISAAPSGSSYGKPWTNGVGGHHPHALPHAKPPVESGGGK
LLPCTGDYMNMSPVGDSNTSSPSEGYYGPEDPQHKPVLSYYSLPRSFKHTQHPGEPEEGG
RHHHLRLSSSSGRLLYTATAEDSSSSTSSDSLGGGYCGARPEPGLPHPHHHVLGLPRKVD
TAAQTNSRLARPTRLSLGDPKASTLPRVREQQQQPSLHPPEPKSPGEYVNIEFGSGQPGY
LAGPGTSHSSPSVRCPPQLHPAPREETGSEEYMNMDLGPGRRATWQESSGVELGRVGPAP
PGAATICRPTRSVPNSRGDYMTMQIGCPRQSYVDTSPVAPVSYADMRTGIAAEKVSLPRT
AGAAPPPPTTTSASAAPQGAAEQAAHSSLLGGPQGPGGTSAFTRVNLSPNHNQSAKVIRA
DTQGCRRRHSSETFSAPTRAGNTVSFGAGAAVGGSGGGSGSSSSGGEDVKRHSSASFENV
WLRPGDLGGASKETAPGCGAAGGLENSLNYIDLDLAKDVKQRPQECPPQQQSLPPPPPHQ
PLGSNEGSSPRRSSEDLSTYASISFQKQPEDRQ
NT seq
3702 nt
NT seq
+upstream
nt +downstream
nt
atggcgagccctccagataccgatggcttttcagacgtgcgcaaggtgggctacctgcgc
aaacccaagagtatgcacaagcgctttttcgtgctgcgggcggccagcgaggccgggggc
ccggcgcgcctggagtactacgagaacgagaagaagtggcggcacaggtcgagcgccccc
aaacgctccatccccctggagagctgtttcaacatcaacaagcgggctgactccaagaac
aagcacctggtggctctctacacccgagacgagcactttgccattgcggccgagagcgag
gccgagcaagacagctggtaccaggctcttctgcagctgcacaatcgagcaaaggcccac
catgacggggctggaggtggaggctgtggcggcagctgcagcggcagctcgggcgttgga
gaggccggggaggacttgagctatgacacgggcccaggacccgcgttcaaggaggtctgg
caggttatcctgaaacccaagggcctaggccagacaaagaacctgattggcatctaccgc
ctctgcctgaccagcaagaccatcagctttgtgaagctcaactcggaggcagcggccgtg
gtgctgcagctgatgaacatccgacggtgcggtcactcagagaacttcttcttcatcgag
gtgggtcgttccgccgtgacagggcccggcgagttctggatgcaggtggatgactccgtg
gtggcccagaacatgcacgagaccattctggaggccatgcgggccatgagcgacgagttt
cgcccgcgcagcaaaagccagtcttcgtccagttgctccaaccccatcagcgttcccctg
cgcaggcaccatctcaacaaccccccgcccagccaggtggggctgactcgccggtctcgc
acggagagcatcactgccacctcccctgccagtatggtgggggggaagccaggctccttc
cgggtgcgcgcctccagcgacggcgagggcaccatgtcccggccggcctcggtggacggc
agtcccgtaagccctagcaccaacaggacccacgccctccgccaccgaggcagctccagg
ctgcaccctccgctcaaccacagccgctccattcccatgccttcttctcgctgctcaccc
tcagccaccagcccagtgagtctgtcttccagcagtaccagcggccacggctccacctcg
gactgcctcttcccgaggcgctccagtgcttccgtgtctggctctcctagcgatggcggc
ttcatctcttccgatgagtacggttctagtccctgtgatttccgaagttccttccgcagt
gtcaccccggattccctgggccacaccccaccagccaggggcgaggaggagctgagtaat
tatatctgcatgggcggcaagggagcctccaccttggctgctcccaacggccactacatt
ttgtccaggggtggcaacggccatcgctacctcccaggtgctaacctggggataagcccg
gcgctggctggagaggaagccgccggtgcagcagatctggagaaccggtttcggaagaga
actcactccgcgggcacgtcccctaccatcacccatcagaagactccctcccagtcttca
gtggcttccattgaggagtacacagagatgatgcccgtggcctacccaccaggaggtggc
agcggaggccggctgcccggctaccggcattccgccttcgtgcccacccactcctatcct
gaagagggtctagagatgcaccccttggagcgtcgtgggggccaccaccgactggacacc
tccgccctccacactgacgatggctacatgcccatgtccccaggcgtggcgccagtgccc
agcaaccgtaaagggaatggagactatatgcccatgagccccaagagtgtctccgccccg
cagcagatcatcaaccccatcagacgccaccctcagagggtggaccccaatggctacatg
atgatgtctcccagcggaagttgctcccctgacgttggcggtggctccagcagcagcggc
agcatcagcgcagccccttccgggagcagctatgggaagccatggacaaacggggtaggg
ggccaccatccccatgccctgcctcacgccaaaccccctgttgagagcggtggtggcaag
ctcttgccttgcacgggcgactacatgaacatgtcacctgtgggagactccaacaccagc
agcccctcggaaggctactacggcccggaagatccccagcacaagccagtcctctcctat
tactcgttgccaaggtcctttaagcacacccagcaccccggagagccagaggagggtggc
aggcaccaccatcttcgcctctcttctagctccggacgccttctctacactgccaccgcg
gaggattcctcctcttctaccagcagcgacagcctgggtgggggttactgtggggctcgg
ccagagcccggcctcccgcatccccaccaccacgttctggggctgccccgaaaggtagac
acggctgcccagaccaacagccgcctggctcggcccacaaggctttccttgggggatccc
aaagcaagcaccttaccaagggtccgagagcagcagcagcagccttccctgcaccctcct
gagcccaagagcccgggagagtatgtgaatattgaattcgggagtggccagcctggctat
ttagctggccccgggacttcccatagctctccttcagtccggtgtccaccccagctccac
ccagctcccagagaagaaactggctcggaagagtacatgaacatggacttggggccaggc
cggagggcgacctggcaggagagtagtggagttgagttgggcagagtaggccctgcacct
ccaggggctgctaccatttgcaggccaacccggtcggtgccaaatagccgtggtgactac
atgaccatgcagataggttgtcctcgtcaaagctatgtggatacctcaccagtggccccc
gtcagctatgctgacatgcggacaggcatcgctgccgagaaggtgagcctgcccagaacc
gcaggggctgctccccctccacccaccacaacctctgcttctgctgcgcctcagggagca
gctgagcaggctgctcactcttccctgctgggaggccctcagggacctgggggcacgagt
gcattcaccagggtgaacctcagtcccaaccataaccagagtgccaaagtcattcgtgca
gacactcaagggtgccggaggaggcatagctccgagaccttctcagcaccgactcgggct
ggcaacacggtgtcctttggagcaggggctgcagtagggggcagtggtggcggcagcggc
agcagcagcagtggcggcgaggatgtaaagcgccacagctctgcatcctttgagaacgtg
tggctgagacctggggacctagggggagcttccaaggagacggctccggggtgtggagct
gctgggggtttggagaacagtcttaactatatagacctagatttggccaaggacgttaaa
cagcgccctcaggagtgcccccctcaacagcagtccctgccaccccctccccctcaccag
cccttaggcagcaatgagggcagctccccgagacgctccagtgaggatttaagcacctat
gccagcatcagcttccagaagcagccagaggaccgtcagtag
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