KEGG   Meriones unguiculatus (Mongolian gerbil): 132656958
Entry
132656958         CDS       T05884                                 
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 6-like
  KO
K00070  3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
Organism
mun  Meriones unguiculatus (Mongolian gerbil)
Pathway
mun00140  Steroid hormone biosynthesis
mun01100  Metabolic pathways
mun04913  Ovarian steroidogenesis
mun04925  Aldosterone synthesis and secretion
mun04927  Cortisol synthesis and secretion
mun04934  Cushing syndrome
Module
mun_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
mun_M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
mun_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:mun00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    132656958
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    132656958
   04925 Aldosterone synthesis and secretion
    132656958
   04927 Cortisol synthesis and secretion
    132656958
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    132656958
Enzymes [BR:mun01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.145  3beta-hydroxy-Delta5-steroid dehydrogenase
     132656958
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.3  Transposing C=C bonds
    5.3.3.1  steroid Delta-isomerase
     132656958
SSDB
Motif
Pfam: 3Beta_HSD Epimerase NAD_binding_4 Polysacc_synt_2 GDP_Man_Dehyd NAD_binding_10 NmrA KR RmlD_sub_bind Ldh_1_N Sacchrp_dh_NADP DapB_N
Other DBs
NCBI-GeneID: 132656958
NCBI-ProteinID: XP_060248985
LinkDB
Position
10:106428932..106435252
AA seq 262 aa
MPGWSCLVTGAGGFLGQRIIHMLVQEKDLEEIRVLDKVFRPETRKEFFNLKTNTKVSVLE
GDILDAQYLKRACQGISVVIHTAAVIDVSGVIPRQTMLDVNLKGTKNLLEACVQASVPVF
IFTSSVEVAGPNSYKQIILDGHEEDSLESILSDPYPYSKKMAEKAVLAANGCTLRNGGTL
HTCALRPMYINGEKSSFLYDTVTCALKNKGVLDTTGKFSRANPTRKPIMISAMSPVSPGR
KPSRIPQSGSGQHKETMNSKTR
NT seq 789 nt   +upstreamnt  +downstreamnt
atgcctgggtggagctgcctggtgactggagcaggagggtttctgggccagagaatcatc
cacatgttggtgcaggagaaagacctggaggagatcagggtcctggacaaggtcttcaga
ccagaaaccaggaaagaattcttcaacctcaagacaaacacaaaggtgtcagtgttggag
ggagacattctggatgcccagtacctgaagagagcctgccagggcatctctgtggtcatc
cacaccgctgctgtcattgatgtctcaggggtcattcccagacagaccatgctagatgtc
aatctgaaaggtaccaagaacctattggaagcctgtgtccaagctagtgtgccagtcttc
atcttcaccagctcagttgaggtggcagggcccaactcctacaagcagatcatcttggat
ggccatgaagaagacagtctagaaagtatattgtctgatccatacccatacagcaaaaag
atggctgagaaggcagtgctggcagccaatgggtgtaccctgagaaatggtggcacttta
catacttgtgccttaaggcccatgtacattaatggggaaaaaagctcattcctttatgac
acagtaacttgtgctctgaaaaataagggtgttttggatactactggcaaattctctaga
gccaaccctacaagaaagcccatcatgatctcggctatgagccctgtgtcacctgggagg
aagccaagcagaataccgcagagtggatcgggacagcacaaagagacaatgaactcaaag
actcggtga

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