KEGG   Meriones unguiculatus (Mongolian gerbil): 132657118
Entry
132657118         CDS       T05884                                 
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1-like
  KO
K00070  3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
Organism
mun  Meriones unguiculatus (Mongolian gerbil)
Pathway
mun00140  Steroid hormone biosynthesis
mun01100  Metabolic pathways
mun04913  Ovarian steroidogenesis
mun04925  Aldosterone synthesis and secretion
mun04927  Cortisol synthesis and secretion
mun04934  Cushing syndrome
Module
mun_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
mun_M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
mun_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:mun00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    132657118
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    132657118
   04925 Aldosterone synthesis and secretion
    132657118
   04927 Cortisol synthesis and secretion
    132657118
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    132657118
Enzymes [BR:mun01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.145  3beta-hydroxy-Delta5-steroid dehydrogenase
     132657118
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.3  Transposing C=C bonds
    5.3.3.1  steroid Delta-isomerase
     132657118
SSDB
Motif
Pfam: 3Beta_HSD Epimerase NAD_binding_4 GDP_Man_Dehyd NAD_binding_10 Polysacc_synt_2 NmrA KR
Other DBs
NCBI-GeneID: 132657118
NCBI-ProteinID: XP_060249324
LinkDB
Position
10:106814180..106822791
AA seq 361 aa
MTPSGLEGLSLNSKDHIKVKGAVRWTSNLKAALCSTDLKTNTKVSVLEGDILDAQYLKRA
CQGISVVIHTAAVIDVSGVIPRQTMLDVNLKGTKNLLEACVQASVPVFIFTSSVEVAGPN
SYKQIILDGHEEDNLESIWSDPYPYSKKMAEKAVLAANGCTLRNGGTLHTCALRPMYING
EKSSFLYDTVTCALKNKGVLDTTGKFSRANTVYVDNVAWAHILAARGLRDPKKSPSIKGQ
FYYISDDTPHQSYDDLNYALSKKWGLRPDSSWSLPLPLLYWLAFLLETVSFLLRPVYNYR
PPFTCHLVTLSNSTFAFSYKKAQHDLGYEPCVTWEEAKQKTSEWIGTLVEQHKETVNSKT
R
NT seq 1086 nt   +upstreamnt  +downstreamnt
atgaccccctcgggcttggagggtcttagccttaacagcaaggatcatatcaaggtgaaa
ggtgctgtccggtggacatccaacctgaaagctgccttgtgttccacagacctcaagaca
aacacaaaggtgtcagtgctggagggagacattctggatgcccagtacctgaagagagcc
tgccagggcatctctgtggtcatccacaccgctgctgtcattgatgtctcaggggtcatt
cccagacagaccatgctagatgtcaatctgaaaggtaccaagaacctactggaagcctgt
gtccaagctagtgtgccagtcttcatcttcaccagctcagttgaggtggcagggcccaac
tcctacaagcagatcatcttggatggccatgaagaagacaatctagaaagtatatggtct
gatccatacccatacagcaaaaagatggctgagaaggcagtgctggcagccaatgggtgt
accctgagaaatggtggcactttacatacttgtgccttaaggcccatgtacattaatggg
gaaaaaagctcattcctttatgacacagtaacttgtgctctgaaaaataagggtgttttg
gatactactggcaaattctctagagccaacacagtgtatgtggacaatgttgcctgggca
cacattctggctgccaggggcctacgagaccccaagaagtcccccagcatcaaaggacag
ttctactacatctcagatgacacccctcaccaaagctatgatgatttaaattatgccctg
agcaagaaatggggcctccgccctgattccagttggagccttcctctgcccctgctctac
tggcttgccttcctgctggaaactgtgagcttcctgctgcgtccagtctacaactaccgg
cccccctttacctgccacttggttacgctctccaacagcacatttgccttctcctacaag
aaagcccagcatgatctcggctatgagccctgtgtcacctgggaggaagccaagcagaaa
acatcagagtggatcgggacactagtggaacagcacaaggaaacagtgaactcaaagact
cggtga

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