Candidatus Mycobacterium wuenschmannii: PT015_07455
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Entry
PT015_07455 CDS
T09639
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mwu
Candidatus Mycobacterium wuenschmannii
Pathway
mwu00010
Glycolysis / Gluconeogenesis
mwu00020
Citrate cycle (TCA cycle)
mwu00620
Pyruvate metabolism
mwu00785
Lipoic acid metabolism
mwu01100
Metabolic pathways
mwu01110
Biosynthesis of secondary metabolites
mwu01120
Microbial metabolism in diverse environments
mwu01200
Carbon metabolism
mwu01210
2-Oxocarboxylic acid metabolism
Module
mwu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mwu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
PT015_07455 (aceE)
00020 Citrate cycle (TCA cycle)
PT015_07455 (aceE)
00620 Pyruvate metabolism
PT015_07455 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
PT015_07455 (aceE)
Enzymes [BR:
mwu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
PT015_07455 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
WIM89273
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Position
1533820..1536609
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AA seq
929 aa
AA seq
DB search
MTTEFVRHDLAKNPTGTSEPDRVRVIREGVASYLPDIDPEETAEWLESFDELLERQGPAR
ARYLMLRLLERAGEQRVALPSLTSTDYVNTIPTEMEPWFPGDEDVERRFRAWIRWNAAIM
VHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKSHPGGGDQVFIQGHASPGIYARAF
LEGRLSADQLDGFRQEHSHPGGGLPSYPHPRLMPNFWEFPTVSMGLGPMNAIYQARFNHY
LHDRGLKDTSDQHVWAFLGDGEMDEPESRGLIQVAANEALDNLTFVINCNLQRLDGPVRG
NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDGDYQTYKANDG
AYVRDHFFGRDPRTKALVEPMTDAEIWNLKRGGHDYRKVYAAYRAAVDHHGQPTVILAKT
IKGYSLGAHFQGRNATHQMKKLALQDLKDFRDAIRIPITDEQLEQDPYLPPYYHPGPEAP
EIRYLLERRHALGGFVPDRRTKTKTLRLPGRDIYAPLKKGSGHQEVATTMATVRTFKELL
RDKEIGDRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESEVGQILH
EGINEAGSSASFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDNLWAAADQMTRGFLLGA
TAGRTTLTGEGLQHADGQSLLLAATNPAVLSYDPAFAYEIAHIIEAGLARMYGENAENVF
YYLTIYNEPYLQPAEPENFDPEGVLRGIYRYQRAGQSRTNSANILASGVSMPAAVQAAEM
LAAEWDVAADVWSVTSWSELNRDGVAIQKQRLRHPDQPAAEPYVTQALSKATGPFVAVSD
WMRAVPEQIRPWVPGSYVTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALARDGEID
PSVPVAAARQYRIDDVQAAQVSYVDTGSA
NT seq
2790 nt
NT seq
+upstream
nt +downstream
nt
ttgaccaccgagttcgtccgccacgatctggccaagaatccaaccggcacaagcgaaccc
gaccgcgtgcgggtgatccgcgagggcgtcgcgtcctacctgccggacatcgacccggag
gaaaccgccgagtggctggagtccttcgacgaactcctcgagcgccagggtccggcgcgg
gcgcggtatctgatgctgaggctgctggagcgcgcaggcgagcagcgagtggcgctgccg
tcgctgacgtcgaccgattacgtcaacacgatcccgaccgagatggagccctggttcccc
ggtgacgaggacgtcgagcgtcgcttccgggcctggatccggtggaacgccgcgatcatg
gtgcaccgcgcccagcgtccgggagtcggtgtgggcggccacatttcgacctacgcgtcg
tcggcggcgctctacgaggtcgggttcaaccactttttccgcggcaagagccatcccggt
ggtggcgatcaggtcttcatccagggccacgcctccccgggcatttacgcccgcgcgttc
ctcgagggccgactgtcggccgaccagttggacggcttccggcaggagcacagtcatccc
ggcggcgggctgccgtcgtatccgcacccgcggttgatgccgaacttctgggagttcccg
acggtgtcgatgggcctgggccccatgaacgcgatctatcaggcccggttcaaccactac
ctgcacgaccgcggcctcaaggacacctccgaccagcacgtgtgggcgttcctcggcgac
ggcgagatggacgagccggagagccgcggcctcatccaggtggccgccaacgaggccttg
gacaacctgacgttcgtgatcaactgcaatctgcagcgtcttgatggcccggtgcgcggc
aacggcaagatcatccaggagctggagtcgttcttccggggcgccggctggaacgtcatc
aaggtggtgtggggtcgcgaatgggacgcgttgctgcacgccgaccgggacggcgcgctg
gtgaacctgatgaacaccacgcccgacggtgactatcagacctataaggccaacgacggc
gcctacgtccgcgaccatttcttcggccgcgaccctcgtaccaaggcgctcgtcgagccg
atgaccgacgccgagatctggaatctgaagcgcggcggccacgactaccgcaaggtgtac
gccgcctaccgcgccgccgtcgatcatcacggtcagccgacggtgatcctggccaagacc
atcaagggctactcgctgggtgcccacttccagggccgcaacgccacccaccagatgaaa
aagcttgcgctgcaagacctcaaggacttccgcgatgcgatccggattccgatcaccgat
gagcaactcgagcaggatccctacctgccgccgtactaccaccccggccccgaggcgccg
gagatccgctacctgctcgaacgtcgccatgcgctcggcggtttcgtgcccgaccggcgt
accaagaccaagaccctgcgactgcccggccgcgacatctatgcgccgctgaagaagggg
tcgggccaccaggaggtcgccaccacgatggcgaccgtccgcacgttcaaggaactgttg
cgggacaaagaaattggtgatcggatcgtcccgatcatccccgacgaggcccgcacgttc
ggcatggactcgtggttcccgtcgctgaagatctacaaccgcaacggccagctctacacc
gctgtcgacgccgagctcatgttggcctacaaggaatctgaagtcggtcagatcctgcac
gagggcatcaacgaggccggctcgtcagccagtttcatcgcggccggtacgtcgtatgcg
acgcacaacgagccgatgatcccgatctacatcttctattccatgttcgggttccagcgc
accggcgacaacctgtgggccgccgccgaccagatgacgcgcggcttcctgttgggcgcc
accgccggtcgcaccaccctgaccggcgagggcctgcagcacgcggacggtcagtcgctg
ctgctcgcggccaccaatcccgctgtgctgtcctacgatccggcgttcgcctacgagatc
gcccacatcatcgaggccgggttggcgcggatgtacggcgagaacgccgagaacgtcttc
tactacctgacgatctacaacgagccgtacctgcagcccgcggagccggagaacttcgac
cccgagggcgtgctgcggggcatctaccgctaccagcgggccggccagagccggaccaat
tccgccaacatcctggcgtcgggggtgtcgatgcccgccgcggtgcaggccgccgagatg
ctggccgccgaatgggacgtcgccgccgacgtgtggtcggtgacgagttggagtgagctc
aaccgcgacggcgtcgcgatccagaagcagcgcctgcggcatccggaccagcccgccgcc
gaaccgtatgtgacgcaggcgctatccaaggcgaccggcccgttcgtcgcggtctcggac
tggatgcgcgcggtgcccgagcagatccggccctgggtgccgggcagctacgtcacgctg
ggcaccgacgggttcggcttctccgacacccggccggcggcccggcgttacttcaacacc
gatgccgagtcgcaggtcgtcgcggtgctggaggcgctggcccgcgacggggagatcgac
ccatcggtgccggtcgcggccgcgcggcagtaccgcatcgacgacgtccaagccgcgcag
gtgtcctacgtcgacaccggcagcgcctga
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