Myotis brandtii (Brandt's bat): 102245460 Help Entry 102245460         CDS       T02920                                  Symbol PTK2 Name (RefSeq) protein tyrosine kinase 2   KO K05725   focal adhesion kinase 1 [EC:2.7.10.2] Organism myb  Myotis brandtii (Brandt's bat) Pathway myb01522   Endocrine resistance myb04012   ErbB signaling pathway myb04062   Chemokine signaling pathway myb04148   Efferocytosis myb04151   PI3K-Akt signaling pathway myb04360   Axon guidance myb04370   VEGF signaling pathway myb04510   Focal adhesion myb04670   Leukocyte transendothelial migration myb04810   Regulation of actin cytoskeleton myb04935   Growth hormone synthesis, secretion and action myb05100   Bacterial invasion of epithelial cells myb05135   Yersinia infection myb05146   Amoebiasis myb05163   Human cytomegalovirus infection myb05165   Human papillomavirus infection myb05170   Human immunodeficiency virus 1 infection myb05200   Pathways in cancer myb05202   Transcriptional misregulation in cancer myb05205   Proteoglycans in cancer myb05208   Chemical carcinogenesis - reactive oxygen species myb05222   Small cell lung cancer myb05417   Lipid and atherosclerosis myb05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:myb00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     102245460 (PTK2)    04370 VEGF signaling pathway     102245460 (PTK2)    04151 PI3K-Akt signaling pathway     102245460 (PTK2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     102245460 (PTK2)   09144 Cellular community - eukaryotes    04510 Focal adhesion     102245460 (PTK2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     102245460 (PTK2)  09150 Organismal Systems   09151 Immune system    04670 Leukocyte transendothelial migration     102245460 (PTK2)    04062 Chemokine signaling pathway     102245460 (PTK2)   09152 Endocrine system    04935 Growth hormone synthesis, secretion and action     102245460 (PTK2)   09158 Development and regeneration    04360 Axon guidance     102245460 (PTK2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102245460 (PTK2)    05202 Transcriptional misregulation in cancer     102245460 (PTK2)    05205 Proteoglycans in cancer     102245460 (PTK2)    05208 Chemical carcinogenesis - reactive oxygen species     102245460 (PTK2)   09162 Cancer: specific types    05222 Small cell lung cancer     102245460 (PTK2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102245460 (PTK2)    05163 Human cytomegalovirus infection     102245460 (PTK2)    05165 Human papillomavirus infection     102245460 (PTK2)   09171 Infectious disease: bacterial    05135 Yersinia infection     102245460 (PTK2)    05100 Bacterial invasion of epithelial cells     102245460 (PTK2)   09174 Infectious disease: parasitic    05146 Amoebiasis     102245460 (PTK2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102245460 (PTK2)    05418 Fluid shear stress and atherosclerosis     102245460 (PTK2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102245460 (PTK2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:myb01001]     102245460 (PTK2)    01009 Protein phosphatases and associated proteins [BR:myb01009]     102245460 (PTK2) Enzymes [BR:myb01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      102245460 (PTK2) Protein kinases [BR:myb01001]  Non-receptor tyrosine kinases   FAK family    102245460 (PTK2) Protein phosphatases and associated proteins [BR:myb01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      102245460 (PTK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Focal_AT Pkinase FERM_C_FAK1 FERM_N_2 FERM_M Kinase-like Haspin_kinase FERM_F2 GIT1_C ABC1 TPR_TNPO3_IPO13_3rd Motif Other DBs NCBI-GeneID:  102245460 NCBI-ProteinID:  XP_005877857 LinkDB All DBs Position Un AA seq 1099 aa AA seqDB search MLLELAGRQALKPAGSGCMEKSGCSPFPVCWAKEYDRYLASSKIMAAAYLDPNLNHTPNS SAKTHLGTGAERSPGAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHK VKHVACYGFRLSHLRSEEVHWLHLDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQ FTEDKPTLNFFYQQVKSDYMLEIADQVDQDIALKLGCLEIRRSYWEMRGNALEKKSNYEV LEKDVGLKRFFPRSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE CFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQTIQYSNSEDKDRKGML QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGASQSFIIRPQKEGERALPSIPKL ANSEKQGVRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDV HQGIYVSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVW IIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSS NDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEIL MHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL STILEEEKAQHEERVRMESRRQVAVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHM VQTNHYQVSGYPGSHGIPAMAGSLYPGQASLLDQTDSWNHRPQEMCMWPPSVEDPAALDL RGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSVDREDASLQGPTG NQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPGDSYNEGVKPWRLQPQEISPPP TANLDRSNDRVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIP GLPASTHREVEMAQKLLNSDLGELISKMRLAQQHVLTSLQQEYKKQMLTAAHALAVDAKN LLDVIDQARLKMLGQARPH NT seq 3300 nt NT seq  +upstreamnt  +downstreamnt atgttgctggaactggcgggccgacaggccctgaaaccagcagggtccggctgtatggag aagagcggctgtagcccattcccagtgtgttgggctaaagaatatgacaggtacctagca tctagcaaaataatggcagctgcttacctggacccaaacttgaatcacacaccgaattcg agtgccaagacgcacctgggtactggtgcggaacggtccccgggagccatggagcgagtg ctaaaagtctttcattattttgaaagcaacagcgagccgaccacgtgggccagtattatc aggcatggagatgctacggatgtcaggggcatcattcagaagatcgtggacagtcacaaa gtgaagcacgtggcctgctacggatttcggctcagtcacctccggtcagaggaggtgcac tggctccacctggacatgggtgtctccagcgtgagggagaagtacgagctcgcacacccg ccggaggagtggaagtatgaattgagaattcgttatttgccaaaaggatttctaaaccag tttactgaggacaagccaactttgaatttcttctatcaacaggtgaagagtgattatatg ttggagatcgcggaccaagtagaccaggacatcgctttgaagttgggttgtctagaaata cggcgatcatactgggagatgcggggcaatgcactagagaagaagtctaactatgaagta ttagaaaaagatgttggtttgaagcggtttttccccaggagtttactggattctgtcaag gccaaaacactcagaaaactgatccagcagactttcaggcagtttgccaacctcaaccgc gaggagagcatcctgaagttcttcgagatcctctccccagtgtacagattcgacaaggag tgcttcaagtgcgcgctcgggtcaagctggattatttcggtggagctggcgatcggcccc gaggaaggcatcagctacctcacagacaaaggctgcaatcccacacatctggccgacttc aatcaagtgcagaccattcagtattcaaacagcgaagacaaggacaggaaaggaatgctc cagctcaagatagcgggcgcgcctgagcctctgacggtgacagcaccgtccctgaccatc gccgagaacatggccgacttgatcgatgggtactgccggctggtgaacggagcctcccag tccttcatcatccgaccccagaaagaaggcgaacgggctttgccgtcaataccaaagctg gccaacagcgagaagcagggcgtgcggacacatgcagtctccgtgtcagaaacggacgac tatgctgagatcatcgacgaagaggacacctacaccatgccctcaaccagagattatgag attcaaagagaaagaatagagctgggacgatgtattggagaaggccagttcggagatgtc caccaaggcatttacgtgagcccagagaatccggctttggcggttgcaattaaaacatgt aaaaactgtacttccgacagcgtgagagagaaattccttcaagaagccttaaccatgcgc cagtttgaccaccctcatatcgtgaagctgattggcgtcatcacggagaaccctgtctgg atcatcatggagctgtgcactctcggagagctgcggtcatttctgcaagtccggaagtac agtttggatctggcgtccttgatcctgtacgcctaccagcttagcacagctctcgcgtac ctggagagcaagagatttgtgcacagggacattgctgctcggaatgttctggtgtcctca aatgattgcgtgaaattaggagactttggattatcccgatacatggaagacagtacttac tacaaagcttccaaaggaaaattgcctattaaatggatggctccagagtcgatcaatttt cgacgctttacctcagctagcgatgtgtggatgtttggtgtatgtatgtgggagatactg atgcatggtgtgaagccttttcaaggagtgaagaacaatgatgtgatcgggcgcattgag aatggggagagattgccaatgcctccaaattgccctcccaccctctacagccttatgacg aaatgctgggcctatgaccccagcaggcggccccggttcactgagctcaaggctcagctc agcacaatcctggaggaggagaaggctcagcacgaggagcgcgtgaggatggagtccagg cgacaggtcgccgtgtcctgggactccggagggtccgacgaagctccgcccaagcccagc aggcctggttatcctagtccgaggtccagcgaagggttttatcccagcccacagcacatg gtgcagaccaaccattaccaggtctctggctaccctggctcccacggaatcccagccatg gcaggcagcctgtacccggggcaggcatccctcttggaccagacagactcgtggaatcac agaccccaggagatgtgcatgtggccgcccagcgtggaggaccctgcggcgctggacctg cgcgggatcggacaggtgttgcccacacacctgatggaggagcggctgatccggcagcag caggagatggaggaagaccagcgctggctggagaaagaggagaggttcctgaaacccgac gtgcggctctcccgaggcagcgtggacagggaggacgcgagtctccagggcccgactgga aaccagcacatctaccagccggtggggaagccagatcctgcagctccaccaaagaagcca ccacgccccggagcccccggccacttgggcagccttgccagcctcagcagccccggggac agctacaacgagggcgtcaagccgtggaggctgcagccccaggagatcagccccccaccc acggccaacctggaccgctccaatgacagggtgtacgagaacgtgacgggcctggtgaag gcggtcatcgagatgtccagcaagatccagcccgccccgcccgaggagtacgtccccatg gtgaaggaagtcggcctggccctgcggacgctgttggccactgtggacgagaccatccct ggcctgccggccagcacgcaccgcgaggtcgagatggcccagaagctgctcaactcggac ctgggcgagctcatcagcaagatgcggctggcccagcagcacgtcctcaccagcctgcag caggagtacaagaagcagatgctgacggccgcgcacgccctggccgtggacgccaagaac ctgctggacgtcattgaccaggccagactgaagatgctggggcaggcgaggccgcactga

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