Myotis brandtii (Brandt's bat): 102246377 Help Entry 102246377         CDS       T02920                                  Symbol CASP8, Caspase-8 Name (RefSeq) caspase 8   KO K04398   caspase 8 [EC:3.4.22.61] Organism myb  Myotis brandtii (Brandt's bat) Pathway myb01524   Platinum drug resistance myb04115   p53 signaling pathway myb04210   Apoptosis myb04215   Apoptosis - multiple species myb04217   Necroptosis myb04620   Toll-like receptor signaling pathway myb04621   NOD-like receptor signaling pathway myb04622   RIG-I-like receptor signaling pathway myb04623   Cytosolic DNA-sensing pathway myb04625   C-type lectin receptor signaling pathway myb04657   IL-17 signaling pathway myb04668   TNF signaling pathway myb04932   Non-alcoholic fatty liver disease myb04936   Alcoholic liver disease myb05010   Alzheimer disease myb05016   Huntington disease myb05022   Pathways of neurodegeneration - multiple diseases myb05132   Salmonella infection myb05134   Legionellosis myb05142   Chagas disease myb05145   Toxoplasmosis myb05152   Tuberculosis myb05160   Hepatitis C myb05161   Hepatitis B myb05162   Measles myb05163   Human cytomegalovirus infection myb05164   Influenza A myb05165   Human papillomavirus infection myb05167   Kaposi sarcoma-associated herpesvirus infection myb05168   Herpes simplex virus 1 infection myb05169   Epstein-Barr virus infection myb05170   Human immunodeficiency virus 1 infection myb05200   Pathways in cancer myb05203   Viral carcinogenesis myb05416   Viral myocarditis myb05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:myb00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     102246377 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     102246377 (CASP8)    04215 Apoptosis - multiple species     102246377 (CASP8)    04217 Necroptosis     102246377 (CASP8)    04115 p53 signaling pathway     102246377 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     102246377 (CASP8)    04621 NOD-like receptor signaling pathway     102246377 (CASP8)    04622 RIG-I-like receptor signaling pathway     102246377 (CASP8)    04623 Cytosolic DNA-sensing pathway     102246377 (CASP8)    04625 C-type lectin receptor signaling pathway     102246377 (CASP8)    04657 IL-17 signaling pathway     102246377 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102246377 (CASP8)    05203 Viral carcinogenesis     102246377 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102246377 (CASP8)    05161 Hepatitis B     102246377 (CASP8)    05160 Hepatitis C     102246377 (CASP8)    05164 Influenza A     102246377 (CASP8)    05162 Measles     102246377 (CASP8)    05168 Herpes simplex virus 1 infection     102246377 (CASP8)    05163 Human cytomegalovirus infection     102246377 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     102246377 (CASP8)    05169 Epstein-Barr virus infection     102246377 (CASP8)    05165 Human papillomavirus infection     102246377 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     102246377 (CASP8)    05134 Legionellosis     102246377 (CASP8)    05152 Tuberculosis     102246377 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     102246377 (CASP8)    05142 Chagas disease     102246377 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     102246377 (CASP8)    05016 Huntington disease     102246377 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     102246377 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102246377 (CASP8)    05416 Viral myocarditis     102246377 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     102246377 (CASP8)    04932 Non-alcoholic fatty liver disease     102246377 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     102246377 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:myb01002]     102246377 (CASP8) Enzymes [BR:myb01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      102246377 (CASP8) Peptidases and inhibitors [BR:myb01002]  Cysteine peptidases   Family C14: caspase family    102246377 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED Motif Other DBs NCBI-GeneID:  102246377 NCBI-ProteinID:  XP_005858275 UniProt:  S7MEE8 LinkDB All DBs Position Un AA seq 504 aa AA seqDB search MDFSNCLYDIGEALSSDEVASLKFLCLDYIPLRKQEPIKDALMLFEKLQEKKMLEEDNLS FLRELLFRIDRLDLLEKRLKTSQEQMWRELQIPGRAQISAYRVMLFQISEDVTAPELKDF KFFLNRELSRCKLVDSMSLLDIFMEMEKRLILGEKNLDTLKRICVQINRSLLDKISAYEK LSKDGGPISDYPREQDSESQEQNCEPREQNFEPPQEQNCELPREQNCEPPREQDSESREQ DSKPQQTADKVYRMKSKPRGYCVIFNNYDFSKARENVPKLCKIKDRTGTDLDAEALRNTF SELHFEVVHYKDATAKTICEILKDYQHMDHNGKDCFVCCILSHGDKGIVYGCDGQEAPIY ELTSYFTGLKCPSLAGKPKIFFIQACQGDNYQKGIAVETDSEEKEAYLEMDSNQKRNIPD EADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNFEVSSKDD KKNMGKQMPQPTFTLRKKLYFPLN NT seq 1515 nt NT seq  +upstreamnt  +downstreamnt atggatttcagcaattgtctgtatgacattggggaagcgctgagcagtgatgaggtggcc tcgctcaagttcctgtgcctggattacatcccactaaggaagcaggagcccatcaaggat gccttgatgctctttgagaaactccaggagaagaaaatgctggaggaggacaacttgtcc ttcctgagggagctgctattccgaatcgacaggctggatctgctggaaaagcgcctgaaa accagccaggagcagatgtggagggagcttcagatcccgggccgggctcagatctctgcg tacagggtcatgcttttccagatttcagaagatgtaactgcaccggaattgaaggacttt aagttttttttgaaccgggagctctccagatgtaaactggtggatagcatgagcttgctt gatatttttatggagatggagaagagactcatccttggggaaaaaaatttggacacccta aaaagaatctgtgtacaaatcaaccggagcctgctggataaaatcagtgcttatgaaaaa ttaagtaaagatggggggccaatttcagactatcctcgagagcaggacagtgagtcacag gaacagaactgtgagccacgggaacagaactttgagccaccacaggaacagaactgtgag ctgccacgggaacagaactgtgagccgccacgggagcaggacagtgagtcacgggaacag gacagtaagccacagcagacagcggacaaagtttaccgaatgaaaagcaaacctcgagga tactgtgtgatctttaataattatgattttagcaaagcacgggagaacgtgcccaaactt tgcaaaattaaggataggactggaacagacttggatgcagaggctttgcgcaacaccttt agtgagcttcattttgaggtagtgcattacaaagatgccacagcaaagactatctgtgag atcctgaaagactaccaacacatggaccacaatggcaaagactgcttcgtctgctgcatc ctttcccatggagacaagggcatcgtctatggctgcgatgggcaggaagcccccatctat gagctgacctcttacttcactggtttgaagtgcccttcccttgcaggcaaaccgaaaatc ttttttatccaggcttgccaaggggataactaccagaaaggcatagctgttgagaccgac tcagaggagaaggaagcctatttagaaatggactcgaaccagaagagaaatatcccagat gaagctgactttctgctggggatggccacagtgaacaactgtgtttcctaccgaaacccc gcagaggggacctggtatatccagtcactgtgccagagtctgagagaaagatgtcctagg ggtgacgacattctcaccatcctcactgaggtaaactttgaagtgagcagtaaggacgac aagaagaatatggggaagcagatgccacaacccactttcacgctgagaaaaaaactctac ttcccccttaattga

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