Myotis brandtii (Brandt's bat): 102249810 Help Entry 102249810         CDS       T02920                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism myb  Myotis brandtii (Brandt's bat) Pathway myb04022   cGMP-PKG signaling pathway myb04068   FoxO signaling pathway myb04081   Hormone signaling myb04140   Autophagy - animal myb04152   AMPK signaling pathway myb04211   Longevity regulating pathway myb04213   Longevity regulating pathway - multiple species myb04910   Insulin signaling pathway myb04920   Adipocytokine signaling pathway myb04923   Regulation of lipolysis in adipocytes myb04930   Type II diabetes mellitus myb04931   Insulin resistance myb04932   Non-alcoholic fatty liver disease myb04935   Growth hormone synthesis, secretion and action myb05010   Alzheimer disease myb05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:myb00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     102249810 (IRS2)    04022 cGMP-PKG signaling pathway     102249810 (IRS2)    04152 AMPK signaling pathway     102249810 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     102249810 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     102249810 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102249810 (IRS2)    04923 Regulation of lipolysis in adipocytes     102249810 (IRS2)    04920 Adipocytokine signaling pathway     102249810 (IRS2)    04935 Growth hormone synthesis, secretion and action     102249810 (IRS2)   09149 Aging    04211 Longevity regulating pathway     102249810 (IRS2)    04213 Longevity regulating pathway - multiple species     102249810 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     102249810 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     102249810 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102249810 (IRS2)    04932 Non-alcoholic fatty liver disease     102249810 (IRS2)    04931 Insulin resistance     102249810 (IRS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS MEKK4_N Motif Other DBs NCBI-GeneID:  102249810 NCBI-ProteinID:  XP_014387416 LinkDB All DBs Position Un AA seq 1056 aa AA seqDB search GLVAPATAAYREVWQGNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLMN IRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPRS KSQSSGSSATHPISVPGARRHHHLVNLPPSQTDLQHPLHHHAGQRPSSGSASASGSPSDP GFMSLDEYGSSPGDVRAFCSHRSNTPESIAETPPAKDGSGSELYGYMTMDRPLSHCGRPY RRVSGDGAQDLDRGLRKRTYSLTTPARQRAVPQPSSASLDEYTLMRATFSGSSGRLCPSC PTSSPRVAYHPYPEDYGDIEIGSHRSSSSNLGTDDGYMPMTPGAALMGGGSGSCKSDDYM PMSPTSVSAPKQILHPRVAAAALPTTGPAAAPAPTNVAGRAFPVNRASYKASSPAESSPE DSGYMRMWCGSKLPTESTDSKQLPNGDYLNMSPSDAGTAGTPPDFFTAALHGAGEMLRSV PGYCYSSLPRSYKAPYTCNGDNDQYVLMSSPVGRILEEERLEPQASVGTTHLASSVVAGV GGGSHAQPPHSVVPSAGRQSGSSSSRPEGFLSQRCRAVRPTRLSLEGLQTLPSMHECPPP PEPKSPGEYINIDFGEAGARLSPPAPPMMSGTPGTSSDSRQRSPLSDYMNLDFNSPKSPK VDKKKXGLPPLPPRPAAPSSSSQLQPPPPPPPGELYRLPPAPTSQGPSAASSSSSETGDN GDYTEMAFGVAATPPQPIVAPPKPDGARVTSPTSGMKRLSLMDHVSGVEAFLQAGQPPDP HRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGS GSGVLGGGDEPPASPRQPQPPLPQQARPWTPSQPGGLVGCPGGSGSPMRRETSAGFQNGL NYIAIDVRDEPGLLPSPQQHPHLHPHPQPGDKSAWGRTRSLGGLISTVGAGSTGGVCGGP GPGALPSNTYASIDFLSHHLKEATIVKDIHDLSRRAPFSSCAEEASWPAAAPSTHSASCS ESLLLLDPLPSTTVATVVGVGQAHLVGQLCVTNPSG NT seq 3171 nt NT seq  +upstreamnt  +downstreamnt gggctggtggcgcccgccacggccgcctaccgcgaggtgtggcaggggaacctgaagccc aagggcctgggccagagcaagaacctgacaggcgtgtaccgcctgtgcctgtctgcgcgc accatcggcttcgtgaagctgaactgcgagcagccgtcggtgacgctgcagctcatgaac atccgccgctgcggccactccgacagcttcttcttcatcgaggtgggtcgctcggctgtc accggccccggcgaactgtggatgcaggctgacgactcagtggtggcccagaacatccat gagaccatcctggaggccatgaaggcgctcaaggagctcttcgagttccggccgcgcagc aagagccagtcgtctggctcctctgccactcaccccatcagcgtccccggcgcgcgccgc caccaccacctggttaacctgcctcccagccagacggacctgcagcaccccctgcaccac cacgcgggccagcggccctccagtggcagcgcttcagcctctggctcccccagcgatccc ggcttcatgtccctggatgagtacggctccagccctggggacgtgagagccttctgcagc cacaggagcaacacgcctgagtccatcgccgagacaccccctgccaaggatgggagtggg agcgagctatacgggtacatgaccatggacaggcccctgagccactgtggccgcccctac cgtcgagtctcaggggacggagcccaggacttggacagagggttgaggaaaaggacttac tccctgaccacacctgcccggcagcgggcggtgccccagccctcctctgcgtccctggat gaatacaccctgatgcgggccaccttctctggcagctctggccgcctctgcccatcctgc cccacgtcttctcccagagtggcctatcacccttatcctgaggactatggtgacattgag attgggtcccataggagctccagcagcaacctgggcacggatgatggctacatgcccatg acccctggagcggccctcatgggtggtggcagtggcagctgcaagagtgacgactacatg cccatgagccccaccagcgtgtctgccccgaagcagatcctgcacccacgggttgctgct gcagctctgcccaccaccggccctgcagcagcgccggcacccaccaatgtggccggccgg gcctttccggtgaacagggccagctacaaggctagctccccggcagaaagctctcctgag gacagtggctacatgcgcatgtggtgtggctccaagctgcctacggagagcaccgacagc aagcagcttcccaacggggactacctcaacatgtcccccagcgacgcgggcaccgcggga accccacccgacttcttcaccgcagccttgcacggcgctggagagatgctcaggagcgtc cctggctactgctacagctccttaccccgctcctacaaggctccctacacctgcaatggg gacaacgaccagtacgtgctcatgagctcccccgtggggcgcatcctggaagaggagagg ctggagcctcaggccagcgtggggaccacgcacctggccagcagcgtggtggctggggtc ggtgggggcagccacgctcagcctcctcactccgtagtgccttctgcagggaggcagagt ggcagcagcagtagccgccccgagggcttcctgagccagcgctgccgggcagtgaggccc acgcgcctgtccctggaggggcttcagaccctgcccagcatgcacgagtgccccccaccg cccgagcccaagagcccgggcgagtacatcaatattgactttggcgaggctggagcgcgc ttgtcgcccccggcccctccgatgatgtctggcaccccgggcacgagcagcgacagccgg cagcgctccccgctctctgactacatgaacctggacttcaattcccccaagtcacccaag gtggataaaaaaaaannagggctcccgccgctgcccccgcgccctgccgccccctcctcc agttcgcagctgcagccacctccgccaccccctccaggggagctgtaccgcctgcctcct gcacccacatcccagggccccagtgctgcctcctcttcgtcctcggagactggggacaat ggtgactacaccgagatggcctttggcgtggctgccaccccgccacaacccatcgtggcc ccccccaagccagatggtgcccgcgtgaccagccccacgtccggcatgaagaggctgagt ctcatggatcacgtgtctggggtcgaggccttcctgcaggctggccagcccccagacccc caccggggggccaaggtcatccgtgcagacccacaggggggccgccgccgccacagctct gagaccttctcctccaccaccactgtgactcccgtgtcgccgtccttcgctcacaacccg aagcgccacaactcggcctccgtggaaaatgtttctctcaggaaaagcagcgaagggagt ggcagcggcgtccttggtgggggtgacgagccccctgcgtcccctcgccagccgcagcca ccactcccccagcaggcgcggccatggacaccaagtcagcctgggggcctggttggctgc cccgggggcagcggctctcccatgcgcagagagacctcagctggcttccagaatggtctc aactacattgccatcgatgtaagggatgagccggggctgttgccgtctccacagcagcac ccacacctgcatccgcatccgcagccaggcgacaagagtgcctggggccggacccgtagc ctcgggggcctcatcagcactgtgggggccggcagcaccggtggggtgtgtggggggcca ggccctggagcgctgccctccaacacctatgccagcattgacttcttgtctcatcacctg aaggaggccaccattgtgaaagacatccatgatctatccaggagagcccccttctcctcc tgtgcggaggaggcctcctggccagcagcagccccctccactcatagtgcctcctgctct gaaagcctgctgctgctggaccccctgccttccaccacagtggccactgtagtcggagta gggcaggcccatttggttgggcagctctgtgttaccaacccatcaggctga

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