KEGG   Myotis brandtii (Brandt's bat): 102253405
Entry
102253405         CDS       T02920                                 
Symbol
PIK3R2
Name
(RefSeq) phosphoinositide-3-kinase regulatory subunit 2
  KO
K02649  phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
myb  Myotis brandtii (Brandt's bat)
Pathway
myb01521  EGFR tyrosine kinase inhibitor resistance
myb01522  Endocrine resistance
myb01524  Platinum drug resistance
myb04012  ErbB signaling pathway
myb04014  Ras signaling pathway
myb04015  Rap1 signaling pathway
myb04024  cAMP signaling pathway
myb04062  Chemokine signaling pathway
myb04066  HIF-1 signaling pathway
myb04068  FoxO signaling pathway
myb04070  Phosphatidylinositol signaling system
myb04071  Sphingolipid signaling pathway
myb04072  Phospholipase D signaling pathway
myb04081  Hormone signaling
myb04140  Autophagy - animal
myb04145  Phagocytosis
myb04150  mTOR signaling pathway
myb04151  PI3K-Akt signaling pathway
myb04152  AMPK signaling pathway
myb04210  Apoptosis
myb04211  Longevity regulating pathway
myb04213  Longevity regulating pathway - multiple species
myb04218  Cellular senescence
myb04360  Axon guidance
myb04370  VEGF signaling pathway
myb04380  Osteoclast differentiation
myb04510  Focal adhesion
myb04517  IgSF CAM signaling
myb04518  Integrin signaling
myb04550  Signaling pathways regulating pluripotency of stem cells
myb04611  Platelet activation
myb04613  Neutrophil extracellular trap formation
myb04620  Toll-like receptor signaling pathway
myb04625  C-type lectin receptor signaling pathway
myb04630  JAK-STAT signaling pathway
myb04650  Natural killer cell mediated cytotoxicity
myb04660  T cell receptor signaling pathway
myb04662  B cell receptor signaling pathway
myb04664  Fc epsilon RI signaling pathway
myb04666  Fc gamma R-mediated phagosome formation
myb04668  TNF signaling pathway
myb04670  Leukocyte transendothelial migration
myb04722  Neurotrophin signaling pathway
myb04725  Cholinergic synapse
myb04750  Inflammatory mediator regulation of TRP channels
myb04810  Regulation of actin cytoskeleton
myb04910  Insulin signaling pathway
myb04914  Progesterone-mediated oocyte maturation
myb04915  Estrogen signaling pathway
myb04917  Prolactin signaling pathway
myb04919  Thyroid hormone signaling pathway
myb04923  Regulation of lipolysis in adipocytes
myb04926  Relaxin signaling pathway
myb04929  GnRH secretion
myb04930  Type II diabetes mellitus
myb04931  Insulin resistance
myb04932  Non-alcoholic fatty liver disease
myb04933  AGE-RAGE signaling pathway in diabetic complications
myb04935  Growth hormone synthesis, secretion and action
myb04960  Aldosterone-regulated sodium reabsorption
myb04973  Carbohydrate digestion and absorption
myb05010  Alzheimer disease
myb05017  Spinocerebellar ataxia
myb05020  Prion disease
myb05100  Bacterial invasion of epithelial cells
myb05135  Yersinia infection
myb05142  Chagas disease
myb05146  Amoebiasis
myb05160  Hepatitis C
myb05161  Hepatitis B
myb05162  Measles
myb05163  Human cytomegalovirus infection
myb05164  Influenza A
myb05165  Human papillomavirus infection
myb05166  Human T-cell leukemia virus 1 infection
myb05167  Kaposi sarcoma-associated herpesvirus infection
myb05168  Herpes simplex virus 1 infection
myb05169  Epstein-Barr virus infection
myb05170  Human immunodeficiency virus 1 infection
myb05171  Coronavirus disease
myb05200  Pathways in cancer
myb05203  Viral carcinogenesis
myb05205  Proteoglycans in cancer
myb05206  MicroRNAs in cancer
myb05207  Chemical carcinogenesis - receptor activation
myb05208  Chemical carcinogenesis - reactive oxygen species
myb05210  Colorectal cancer
myb05211  Renal cell carcinoma
myb05212  Pancreatic cancer
myb05213  Endometrial cancer
myb05214  Glioma
myb05215  Prostate cancer
myb05218  Melanoma
myb05220  Chronic myeloid leukemia
myb05221  Acute myeloid leukemia
myb05222  Small cell lung cancer
myb05223  Non-small cell lung cancer
myb05224  Breast cancer
myb05225  Hepatocellular carcinoma
myb05226  Gastric cancer
myb05230  Central carbon metabolism in cancer
myb05231  Choline metabolism in cancer
myb05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
myb05415  Diabetic cardiomyopathy
myb05417  Lipid and atherosclerosis
myb05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:myb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    102253405 (PIK3R2)
   04014 Ras signaling pathway
    102253405 (PIK3R2)
   04015 Rap1 signaling pathway
    102253405 (PIK3R2)
   04370 VEGF signaling pathway
    102253405 (PIK3R2)
   04630 JAK-STAT signaling pathway
    102253405 (PIK3R2)
   04668 TNF signaling pathway
    102253405 (PIK3R2)
   04066 HIF-1 signaling pathway
    102253405 (PIK3R2)
   04068 FoxO signaling pathway
    102253405 (PIK3R2)
   04070 Phosphatidylinositol signaling system
    102253405 (PIK3R2)
   04072 Phospholipase D signaling pathway
    102253405 (PIK3R2)
   04071 Sphingolipid signaling pathway
    102253405 (PIK3R2)
   04024 cAMP signaling pathway
    102253405 (PIK3R2)
   04151 PI3K-Akt signaling pathway
    102253405 (PIK3R2)
   04152 AMPK signaling pathway
    102253405 (PIK3R2)
   04150 mTOR signaling pathway
    102253405 (PIK3R2)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    102253405 (PIK3R2)
   04517 IgSF CAM signaling
    102253405 (PIK3R2)
   04518 Integrin signaling
    102253405 (PIK3R2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    102253405 (PIK3R2)
   04140 Autophagy - animal
    102253405 (PIK3R2)
  09143 Cell growth and death
   04210 Apoptosis
    102253405 (PIK3R2)
   04218 Cellular senescence
    102253405 (PIK3R2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102253405 (PIK3R2)
   04550 Signaling pathways regulating pluripotency of stem cells
    102253405 (PIK3R2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102253405 (PIK3R2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102253405 (PIK3R2)
   04613 Neutrophil extracellular trap formation
    102253405 (PIK3R2)
   04620 Toll-like receptor signaling pathway
    102253405 (PIK3R2)
   04625 C-type lectin receptor signaling pathway
    102253405 (PIK3R2)
   04650 Natural killer cell mediated cytotoxicity
    102253405 (PIK3R2)
   04660 T cell receptor signaling pathway
    102253405 (PIK3R2)
   04662 B cell receptor signaling pathway
    102253405 (PIK3R2)
   04664 Fc epsilon RI signaling pathway
    102253405 (PIK3R2)
   04666 Fc gamma R-mediated phagosome formation
    102253405 (PIK3R2)
   04670 Leukocyte transendothelial migration
    102253405 (PIK3R2)
   04062 Chemokine signaling pathway
    102253405 (PIK3R2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    102253405 (PIK3R2)
   04923 Regulation of lipolysis in adipocytes
    102253405 (PIK3R2)
   04929 GnRH secretion
    102253405 (PIK3R2)
   04915 Estrogen signaling pathway
    102253405 (PIK3R2)
   04914 Progesterone-mediated oocyte maturation
    102253405 (PIK3R2)
   04917 Prolactin signaling pathway
    102253405 (PIK3R2)
   04926 Relaxin signaling pathway
    102253405 (PIK3R2)
   04935 Growth hormone synthesis, secretion and action
    102253405 (PIK3R2)
   04919 Thyroid hormone signaling pathway
    102253405 (PIK3R2)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    102253405 (PIK3R2)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102253405 (PIK3R2)
  09156 Nervous system
   04725 Cholinergic synapse
    102253405 (PIK3R2)
   04722 Neurotrophin signaling pathway
    102253405 (PIK3R2)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102253405 (PIK3R2)
  09158 Development and regeneration
   04360 Axon guidance
    102253405 (PIK3R2)
   04380 Osteoclast differentiation
    102253405 (PIK3R2)
  09149 Aging
   04211 Longevity regulating pathway
    102253405 (PIK3R2)
   04213 Longevity regulating pathway - multiple species
    102253405 (PIK3R2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102253405 (PIK3R2)
   05206 MicroRNAs in cancer
    102253405 (PIK3R2)
   05205 Proteoglycans in cancer
    102253405 (PIK3R2)
   05207 Chemical carcinogenesis - receptor activation
    102253405 (PIK3R2)
   05208 Chemical carcinogenesis - reactive oxygen species
    102253405 (PIK3R2)
   05203 Viral carcinogenesis
    102253405 (PIK3R2)
   05230 Central carbon metabolism in cancer
    102253405 (PIK3R2)
   05231 Choline metabolism in cancer
    102253405 (PIK3R2)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102253405 (PIK3R2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102253405 (PIK3R2)
   05212 Pancreatic cancer
    102253405 (PIK3R2)
   05225 Hepatocellular carcinoma
    102253405 (PIK3R2)
   05226 Gastric cancer
    102253405 (PIK3R2)
   05214 Glioma
    102253405 (PIK3R2)
   05221 Acute myeloid leukemia
    102253405 (PIK3R2)
   05220 Chronic myeloid leukemia
    102253405 (PIK3R2)
   05218 Melanoma
    102253405 (PIK3R2)
   05211 Renal cell carcinoma
    102253405 (PIK3R2)
   05215 Prostate cancer
    102253405 (PIK3R2)
   05213 Endometrial cancer
    102253405 (PIK3R2)
   05224 Breast cancer
    102253405 (PIK3R2)
   05222 Small cell lung cancer
    102253405 (PIK3R2)
   05223 Non-small cell lung cancer
    102253405 (PIK3R2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102253405 (PIK3R2)
   05170 Human immunodeficiency virus 1 infection
    102253405 (PIK3R2)
   05161 Hepatitis B
    102253405 (PIK3R2)
   05160 Hepatitis C
    102253405 (PIK3R2)
   05171 Coronavirus disease
    102253405 (PIK3R2)
   05164 Influenza A
    102253405 (PIK3R2)
   05162 Measles
    102253405 (PIK3R2)
   05168 Herpes simplex virus 1 infection
    102253405 (PIK3R2)
   05163 Human cytomegalovirus infection
    102253405 (PIK3R2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102253405 (PIK3R2)
   05169 Epstein-Barr virus infection
    102253405 (PIK3R2)
   05165 Human papillomavirus infection
    102253405 (PIK3R2)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    102253405 (PIK3R2)
   05100 Bacterial invasion of epithelial cells
    102253405 (PIK3R2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    102253405 (PIK3R2)
   05142 Chagas disease
    102253405 (PIK3R2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102253405 (PIK3R2)
   05017 Spinocerebellar ataxia
    102253405 (PIK3R2)
   05020 Prion disease
    102253405 (PIK3R2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102253405 (PIK3R2)
   05418 Fluid shear stress and atherosclerosis
    102253405 (PIK3R2)
   05415 Diabetic cardiomyopathy
    102253405 (PIK3R2)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    102253405 (PIK3R2)
   04932 Non-alcoholic fatty liver disease
    102253405 (PIK3R2)
   04931 Insulin resistance
    102253405 (PIK3R2)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102253405 (PIK3R2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102253405 (PIK3R2)
   01524 Platinum drug resistance
    102253405 (PIK3R2)
   01522 Endocrine resistance
    102253405 (PIK3R2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:myb04131]
    102253405 (PIK3R2)
Membrane trafficking [BR:myb04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    102253405 (PIK3R2)
SSDB
Motif
Pfam: PI3K_P85_iSH2 SH2 RhoGAP SH3_1 SH3_9 Ribosomal_L22e ODF2_C
Other DBs
NCBI-GeneID: 102253405
NCBI-ProteinID: XP_014401297
LinkDB
Position
Un
AA seq 731 aa
MAGAEGFQYRALYPFRRERPEDLELLPGDVLVVSRAALQGLGVAEGSERCPQNVGWIPGL
NERTRQRGDFPGTYVEFLGPVTLTRPGPRPRGPRPLPARPQEGPPEPGLTLPDLPEQFSP
PDVAPPLLVKLVEAIERTGLDSESLYRPELPPPCTDWSLSDLEQWDSAALADGIKGFLLA
LPAPLVTLEAAAEACRALREQGVNLAFRKTPLRGLGAWTGGEAPVWCLDLPFQVLDSSAR
VYLLSVHCTYISNSWLPTPAWSSALLPSFRVCSRRTEPNPDFPALLVEKLLQEHLEEQEV
APPALPPKPPKVKPAPAGLANGGSPPSLQDAEWYWGDISREEVNDKLRDTPDGTFLVRDA
SSKIQGEYTLTLRKGGNNKLIKVFHRDGHYGFSEPLTFCSVVDLITHYRHESLAQYNAKL
DTRLLYPVSKYQQDQIVKEDSVEAVGAQLKVYHQQYQDKSREXDQLYEEYTRTSQELQMK
RTAIEAFNETIKIFEEQGQTQEKCSKEYLERFRREGNEKEMQRILLNSERLKSRIAEIHE
SRTKLEQELRTQALDNREIDKRMNSLKPDLMQLRKIRDQYLVWLTQKGARQKKINEWLGI
KNETEDQYALMEDEDDXPHHEERTWYVGKINRTQAEEMLNGKRDGTFLIRESSQRGCYAC
SVVVDGDTKHCVIYRTATGLGFAEPYNLYGSLKELVLHYQHTSLVQHNDALTVTLAHPVR
APGPGPPPAAR
NT seq 2196 nt   +upstreamnt  +downstreamnt
atggctggcgctgagggcttccaataccgtgcactgtacccgttccgccgggagcggcca
gaagacctggaactgttgcccggtgacgtgctggtggtgagccgggcagccctgcagggg
ctgggtgtggccgagggcagtgagcgctgcccgcagaacgtgggctggatacctggcctc
aatgagcgaactcggcagcgcggtgacttccctggtacctacgtggagttcctggggcct
gtgaccctgacccggcctggccctcgcccccgtggcccccgtccactgcctgccaggccc
caagaggggccccctgagccaggcctcacgctccctgacctacctgagcagttctcccca
cctgatgtggctcccccactgctggtaaagcttgtggaggccattgagcggacagggcta
gacagcgaatccctctacaggcccgagctgccgcccccgtgcacagactggtccctgagc
gacctagagcagtgggactcggcagccctggccgatggcatcaagggcttcctgctggca
ctgcctgcgccccttgtgacgctggaagccgcggcagaggcctgccgtgccctgcgagaa
caaggggtgaacctggccttcaggaagacccccctccgaggacttggggcctggaccgga
ggagaggcacctgtgtggtgcctggaccttcccttccaggtgctggactcctcagcgcgg
gtgtatttactgagcgtgcactgcacatacataagcaacagttggcttcccacacctgct
tggtcatctgccctgcttcccagctttcgtgtgtgctcacgcaggactgagcccaacccc
gacttcccagctctgctggtggagaagttgcttcaggagcacctggaggagcaggaggtc
gcacccccagctctgccacctaaaccacctaaagtcaagcccgccccagcagggctggct
aatggggggagcccgccctctctgcaggatgctgagtggtactggggtgacatttccagg
gaggaggtgaacgacaaactccgggacacacctgacggcaccttcctggtccgagatgcc
tccagcaagattcagggagagtataccctgacccttaggaaaggtggaaacaacaagcta
attaaggtcttccaccgcgatgggcattatggcttctcggagccgctcaccttctgctcc
gtcgtggacctcatcacccactaccgccatgagtccctggcccagtacaatgccaaacta
gacacacggctcctgtaccccgtgtccaagtaccagcaggaccagattgtcaaggaagat
agcgtggaggcagtgggtgcccagctcaaagtctaccatcagcagtaccaggacaagagc
cgcgagtaagaccagctctacgaggagtacacacgcacctcccaggagctgcagatgaag
cgcaccgcaatcgaggccttcaatgaaaccatcaagatcttcgaagagcagggccagact
caagagaagtgcagcaaggagtatctggagcgcttccggcgtgagggcaatgagaaagag
atgcagaggatcctgctgaactcagaacggctcaagtctcgcatcgccgagatccacgag
agccgcacgaagctggaacaggagctgcggacacaggccttggacaaccgggagatcgat
aagcgcatgaacagcctgaagccagacctcatgcagctgcgcaagatccgagaccagtac
ctggtatggctcacccagaaaggcgcccggcagaagaaaatcaacgagtggttgggaatc
aaaaatgagactgaagaccagtatgcactgatggaggatgaggatgacnctccccaccat
gaggaacgaacctggtatgtgggcaagatcaaccgcacgcaggctgaggaaatgctgaac
ggcaagcgggatgggaccttcctcatccgtgagagcagccagcggggctgctacgcctgc
tctgtggtggtggacggcgataccaagcactgcgtcatctaccgcacggccactggcttg
ggttttgcggagccctacaacctgtacgggtctctgaaggagctggtgctgcattaccag
cacacctccctcgtgcaacacaacgatgcacttaccgtcacactggcccatcccgtgcga
gccccgggtcccggtccacccccggccgcccgctga

DBGET integrated database retrieval system