Myotis davidii (David's myotis): 102753060 Help Entry 102753060         CDS       T02992                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism myd  Myotis davidii (David's myotis) Pathway myd04022   cGMP-PKG signaling pathway myd04068   FoxO signaling pathway myd04081   Hormone signaling myd04140   Autophagy - animal myd04152   AMPK signaling pathway myd04211   Longevity regulating pathway myd04213   Longevity regulating pathway - multiple species myd04910   Insulin signaling pathway myd04920   Adipocytokine signaling pathway myd04923   Regulation of lipolysis in adipocytes myd04930   Type II diabetes mellitus myd04931   Insulin resistance myd04932   Non-alcoholic fatty liver disease myd04935   Growth hormone synthesis, secretion and action myd05010   Alzheimer disease myd05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:myd00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     102753060 (IRS2)    04022 cGMP-PKG signaling pathway     102753060 (IRS2)    04152 AMPK signaling pathway     102753060 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     102753060 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     102753060 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102753060 (IRS2)    04923 Regulation of lipolysis in adipocytes     102753060 (IRS2)    04920 Adipocytokine signaling pathway     102753060 (IRS2)    04935 Growth hormone synthesis, secretion and action     102753060 (IRS2)   09149 Aging    04211 Longevity regulating pathway     102753060 (IRS2)    04213 Longevity regulating pathway - multiple species     102753060 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     102753060 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     102753060 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102753060 (IRS2)    04932 Non-alcoholic fatty liver disease     102753060 (IRS2)    04931 Insulin resistance     102753060 (IRS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS MEKK4_N Motif Other DBs NCBI-GeneID:  102753060 NCBI-ProteinID:  XP_006770771 LinkDB All DBs Position Un AA seq 1059 aa AA seqDB search MAGAPLFNRDSFAAPTTNANTSNTEKSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLM NIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPR SKSQSSVHHHAGQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAE TPPAKDGSGSELYGYMTMDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRAV PQPSSASLDEYTLMRATFSGSSGRLCPSCPTSSPRVAYNPYPEDYGDIEIGSHRSSSSNL GTDDGYMPMTPGAALMGGGSGSCKSDDYMPMSPTSVSAPKQILHPRVAAAALPPTGPAAP APTNAAGRAFPVNRASYKASSPAESSPEDSGYMRMWCGSKLPMESTDSKQLPNGDYLNMS PSDAGTAGTPPDFFTAALHGSGEMLRSVPGYCYSSLPRSYKAPYTCNGDNDQYVLMSSPV GRILEEERLEPQASMGTTHPASSVVAGVGGGSHAQPPHSVVPSAGRQSGSGSGRPEGFLN QRCRAVRPTRLSLEGLQTLPSMHECPLPPEPKSPGEYINIDFGEAGARLSPPAPPMMLAS AASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFNSPKSPKAETQSGDPVGS LDGLLSPEASSGYPPLPPRPAAPSSSSQLQPPPPPPPGELYRLPPAPTSQGPSAASSSSS ETGDNGDYTEMAFGVAATPPQPIVAPAKPDGARVTSPTSGMKRLSLMDHVSGVEAFLQAG QPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRK SSEGSGSGVLGGGDEPPASPRQPQPPLPQQARPWTPSQPGGLVGCPGGIGSPMRRETSAG FQNGLNYIAIDVRDEPGLLPSPQQHPHLHPQPGDKSAWGRTRSLGGLIGTVGASSTAGVC GGPGPGALPASTYASIDFLSHRLKEATIVKDIHDLSGRAPFSSCAEEASWPAAAPSTHSA SCSGSLLLLDPLPSTTVATVVGVGQSRLVGQLCVTNPSG NT seq 3180 nt NT seq  +upstreamnt  +downstreamnt atggctggagcccctctattcaaccgtgacagctttgctgcacctaccaccaatgccaac acaagcaacacagagaaaagcaagaacctgacaggcgtgtaccgcctgtgcctgtccgcg cgcaccatcggcttcgtgaagctgaactgcgagcagccgtcggtgacgctgcagctcatg aacatccgccgctgcggccactccgacagcttcttcttcatcgaggtgggccgctcggct gtcaccggccccggcgaactgtggatgcaggctgacgactcggtggtggcccagaacatc catgagaccatcctggaggccatgaaggcgctcaaggagctcttcgagttccggccgcgc agcaagagccagtcgtctgtgcaccaccacgcgggccagcggccctccagtggcagcgct tcagcctctggctcccccagcgatcccggcttcatgtccctggatgagtacggctccagc cctggggacctgagagccttctgcagccacaggagcaacacgcctgagtccattgccgag acaccccctgccaaggatgggagtgggagcgagctatacgggtacatgaccatggacagg cccctgagccactgtggccgcccctaccgtcgagtctcaggagatggagcccaggacttg gacagagggttgaggaagaggacttactccctgaccacacctgcccggcagcgggcggtg ccccagccctcctctgcgtccctggatgaatacaccctgatgcgggccaccttttctggc agctctggccgcctctgcccatcctgccccacgtcttctcccagagtggcctataaccct tatcctgaggactatggtgacattgagattgggtcccataggagctccagcagcaacctg ggcacggacgatggttacatgcccatgacccctggagcggccctcatgggtggtggcagt ggcagctgcaagagtgacgactacatgcccatgagccccaccagcgtatctgccccgaag cagatcctgcacccacgggttgctgctgcggctctgccccccacaggccctgcagcgccg gcacccaccaatgcggctggcagggcctttccggtgaacagggccagctacaaggctagc tccccggcggaaagctctcctgaggacagtggctacatgcgcatgtggtgtggctccaag ctgcctatggagagcaccgacagcaaacagcttcccaacggggactacctcaacatgtcc cccagcgacgcgggcaccgcgggaaccccacccgacttcttcaccgcagccttgcacggc tctggagagatgctcaggagcgtccctggctactgctacagctccttaccccgctcctac aaggctccctacacctgcaatggggacaacgaccagtacgtgctcatgagctcccccgtg gggcgcattctggaagaggagaggctggagcctcaggctagcatggggaccacgcaccca gccagcagcgtggtggccggggtgggtgggggcagccacgctcagcctcctcactccgta gtgccttctgcagggaggcagagtggcagcggcagtggccgccccgagggcttcctgaac cagcgatgccgggcagtgaggcccacgcgcctgtccctggaggggcttcagaccctgccc agcatgcacgagtgccccctaccgcccgagcccaagagcccgggcgagtacatcaatatt gactttggcgaggctggagcgcgcttgtcgcccccggcccctccgatgatgctggcttcg gcggcctcctcgtcctcgctgctgtctgccagcagcccagcctcgtccctgggctctggc accccgggcacgagcagtgacagccggcagcgctccccgctctctgactacatgaacctg gacttcaattcccccaagtcacccaaggctgagacccagagcggggacccagtgggctcc ttggatggcctcttgtcccctgaggcctcctccgggtacccgccgctgcccccgcgccct gccgccccctcctccagttcgcagctgcagccacctccgccaccccctccaggggagctg taccgcctgcctcctgcacccacatcccagggccccagtgctgcctcctcttcgtcctcg gagactggggacaatggtgactacaccgagatggcctttggcgtggctgccaccccgccg caacccatcgtggcccccgcaaagccagatggtgcccgcgtgaccagccctacgtccggc atgaagaggctgagtctcatggatcacgtgtcgggggtcgaggccttcctgcaggctggc cagcccccagacccccaccggggggccaaggtcatccgtgcagacccacaggggggccgc cgccggcacagctcggagaccttctcctcaaccaccactgtgactcccgtgtcgccgtcc tttgctcacaacccgaagcgccacaactcggcctccgtggaaaatgtctctctcaggaaa agcagtgaagggagtggcagcggcgtccttggtgggggtgacgagccccctgcgtcccct cgccagccgcagccacccctcccccagcaggcccggccatggacaccaagtcagcctggg ggcctggttggctgccccgggggcattggctctcccatgcgcagggagacctcagctggc ttccagaatggtctcaactacattgccatcgatgtcagggatgagccggggctattgccg tctccacagcagcacccacacctgcatccgcagccaggcgacaagagtgcctggggccgg acccgtagcctcgggggtctcatcggcactgtgggggccagcagcaccgcgggggtgtgt gggggtccaggccctggagcgctgcccgccagcacctatgccagcattgacttcttgtcc catcgcctgaaggaggccaccattgtgaaagacatccatgatctatccgggagagccccc ttctcctcctgtgcggaggaggcctcctggccagcagcagccccctccactcatagtgcc tcctgctctggaagcctgctgctgctggaccccctgccttccaccacagtggccactgta gtcggagtagggcagtcccgtttggttgggcagctctgtgttaccaacccatcaggctga

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