Myotis davidii (David's myotis): 102757282
Help
Entry
102757282 CDS
T02992
Symbol
MAP2K2
Name
(RefSeq) mitogen-activated protein kinase kinase 2
KO
K04369
mitogen-activated protein kinase kinase 2 [EC:
2.7.12.2
]
Organism
myd
Myotis davidii (David's myotis)
Pathway
myd01521
EGFR tyrosine kinase inhibitor resistance
myd01522
Endocrine resistance
myd04010
MAPK signaling pathway
myd04012
ErbB signaling pathway
myd04014
Ras signaling pathway
myd04015
Rap1 signaling pathway
myd04022
cGMP-PKG signaling pathway
myd04024
cAMP signaling pathway
myd04066
HIF-1 signaling pathway
myd04068
FoxO signaling pathway
myd04071
Sphingolipid signaling pathway
myd04072
Phospholipase D signaling pathway
myd04140
Autophagy - animal
myd04148
Efferocytosis
myd04150
mTOR signaling pathway
myd04151
PI3K-Akt signaling pathway
myd04210
Apoptosis
myd04218
Cellular senescence
myd04270
Vascular smooth muscle contraction
myd04370
VEGF signaling pathway
myd04371
Apelin signaling pathway
myd04540
Gap junction
myd04550
Signaling pathways regulating pluripotency of stem cells
myd04613
Neutrophil extracellular trap formation
myd04620
Toll-like receptor signaling pathway
myd04650
Natural killer cell mediated cytotoxicity
myd04660
T cell receptor signaling pathway
myd04662
B cell receptor signaling pathway
myd04664
Fc epsilon RI signaling pathway
myd04720
Long-term potentiation
myd04722
Neurotrophin signaling pathway
myd04730
Long-term depression
myd04810
Regulation of actin cytoskeleton
myd04910
Insulin signaling pathway
myd04912
GnRH signaling pathway
myd04915
Estrogen signaling pathway
myd04916
Melanogenesis
myd04917
Prolactin signaling pathway
myd04919
Thyroid hormone signaling pathway
myd04921
Oxytocin signaling pathway
myd04926
Relaxin signaling pathway
myd04929
GnRH secretion
myd04934
Cushing syndrome
myd04935
Growth hormone synthesis, secretion and action
myd05010
Alzheimer disease
myd05022
Pathways of neurodegeneration - multiple diseases
myd05132
Salmonella infection
myd05135
Yersinia infection
myd05160
Hepatitis C
myd05161
Hepatitis B
myd05163
Human cytomegalovirus infection
myd05164
Influenza A
myd05165
Human papillomavirus infection
myd05166
Human T-cell leukemia virus 1 infection
myd05167
Kaposi sarcoma-associated herpesvirus infection
myd05170
Human immunodeficiency virus 1 infection
myd05200
Pathways in cancer
myd05205
Proteoglycans in cancer
myd05206
MicroRNAs in cancer
myd05207
Chemical carcinogenesis - receptor activation
myd05208
Chemical carcinogenesis - reactive oxygen species
myd05210
Colorectal cancer
myd05211
Renal cell carcinoma
myd05213
Endometrial cancer
myd05214
Glioma
myd05215
Prostate cancer
myd05216
Thyroid cancer
myd05218
Melanoma
myd05219
Bladder cancer
myd05220
Chronic myeloid leukemia
myd05221
Acute myeloid leukemia
myd05223
Non-small cell lung cancer
myd05224
Breast cancer
myd05225
Hepatocellular carcinoma
myd05226
Gastric cancer
myd05230
Central carbon metabolism in cancer
myd05231
Choline metabolism in cancer
myd05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
myd00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102757282 (MAP2K2)
04012 ErbB signaling pathway
102757282 (MAP2K2)
04014 Ras signaling pathway
102757282 (MAP2K2)
04015 Rap1 signaling pathway
102757282 (MAP2K2)
04370 VEGF signaling pathway
102757282 (MAP2K2)
04371 Apelin signaling pathway
102757282 (MAP2K2)
04066 HIF-1 signaling pathway
102757282 (MAP2K2)
04068 FoxO signaling pathway
102757282 (MAP2K2)
04072 Phospholipase D signaling pathway
102757282 (MAP2K2)
04071 Sphingolipid signaling pathway
102757282 (MAP2K2)
04024 cAMP signaling pathway
102757282 (MAP2K2)
04022 cGMP-PKG signaling pathway
102757282 (MAP2K2)
04151 PI3K-Akt signaling pathway
102757282 (MAP2K2)
04150 mTOR signaling pathway
102757282 (MAP2K2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
102757282 (MAP2K2)
04148 Efferocytosis
102757282 (MAP2K2)
09143 Cell growth and death
04210 Apoptosis
102757282 (MAP2K2)
04218 Cellular senescence
102757282 (MAP2K2)
09144 Cellular community - eukaryotes
04540 Gap junction
102757282 (MAP2K2)
04550 Signaling pathways regulating pluripotency of stem cells
102757282 (MAP2K2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
102757282 (MAP2K2)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
102757282 (MAP2K2)
04620 Toll-like receptor signaling pathway
102757282 (MAP2K2)
04650 Natural killer cell mediated cytotoxicity
102757282 (MAP2K2)
04660 T cell receptor signaling pathway
102757282 (MAP2K2)
04662 B cell receptor signaling pathway
102757282 (MAP2K2)
04664 Fc epsilon RI signaling pathway
102757282 (MAP2K2)
09152 Endocrine system
04910 Insulin signaling pathway
102757282 (MAP2K2)
04929 GnRH secretion
102757282 (MAP2K2)
04912 GnRH signaling pathway
102757282 (MAP2K2)
04915 Estrogen signaling pathway
102757282 (MAP2K2)
04917 Prolactin signaling pathway
102757282 (MAP2K2)
04921 Oxytocin signaling pathway
102757282 (MAP2K2)
04926 Relaxin signaling pathway
102757282 (MAP2K2)
04935 Growth hormone synthesis, secretion and action
102757282 (MAP2K2)
04919 Thyroid hormone signaling pathway
102757282 (MAP2K2)
04916 Melanogenesis
102757282 (MAP2K2)
09153 Circulatory system
04270 Vascular smooth muscle contraction
102757282 (MAP2K2)
09156 Nervous system
04720 Long-term potentiation
102757282 (MAP2K2)
04730 Long-term depression
102757282 (MAP2K2)
04722 Neurotrophin signaling pathway
102757282 (MAP2K2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102757282 (MAP2K2)
05206 MicroRNAs in cancer
102757282 (MAP2K2)
05205 Proteoglycans in cancer
102757282 (MAP2K2)
05207 Chemical carcinogenesis - receptor activation
102757282 (MAP2K2)
05208 Chemical carcinogenesis - reactive oxygen species
102757282 (MAP2K2)
05230 Central carbon metabolism in cancer
102757282 (MAP2K2)
05231 Choline metabolism in cancer
102757282 (MAP2K2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102757282 (MAP2K2)
09162 Cancer: specific types
05210 Colorectal cancer
102757282 (MAP2K2)
05225 Hepatocellular carcinoma
102757282 (MAP2K2)
05226 Gastric cancer
102757282 (MAP2K2)
05214 Glioma
102757282 (MAP2K2)
05216 Thyroid cancer
102757282 (MAP2K2)
05221 Acute myeloid leukemia
102757282 (MAP2K2)
05220 Chronic myeloid leukemia
102757282 (MAP2K2)
05218 Melanoma
102757282 (MAP2K2)
05211 Renal cell carcinoma
102757282 (MAP2K2)
05219 Bladder cancer
102757282 (MAP2K2)
05215 Prostate cancer
102757282 (MAP2K2)
05213 Endometrial cancer
102757282 (MAP2K2)
05224 Breast cancer
102757282 (MAP2K2)
05223 Non-small cell lung cancer
102757282 (MAP2K2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
102757282 (MAP2K2)
05170 Human immunodeficiency virus 1 infection
102757282 (MAP2K2)
05161 Hepatitis B
102757282 (MAP2K2)
05160 Hepatitis C
102757282 (MAP2K2)
05164 Influenza A
102757282 (MAP2K2)
05163 Human cytomegalovirus infection
102757282 (MAP2K2)
05167 Kaposi sarcoma-associated herpesvirus infection
102757282 (MAP2K2)
05165 Human papillomavirus infection
102757282 (MAP2K2)
09171 Infectious disease: bacterial
05132 Salmonella infection
102757282 (MAP2K2)
05135 Yersinia infection
102757282 (MAP2K2)
09164 Neurodegenerative disease
05010 Alzheimer disease
102757282 (MAP2K2)
05022 Pathways of neurodegeneration - multiple diseases
102757282 (MAP2K2)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
102757282 (MAP2K2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102757282 (MAP2K2)
01522 Endocrine resistance
102757282 (MAP2K2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
myd01001
]
102757282 (MAP2K2)
Enzymes [BR:
myd01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.12 Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
2.7.12.2 mitogen-activated protein kinase kinase
102757282 (MAP2K2)
Protein kinases [BR:
myd01001
]
Serine/threonine kinases: STE group
STE7 family
102757282 (MAP2K2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
Pkinase_fungal
Kinase-like
Haspin_kinase
Seadorna_VP7
APH
Kdo
Motif
Other DBs
NCBI-GeneID:
102757282
NCBI-ProteinID:
XP_015422666
LinkDB
All DBs
Position
Un
AA seq
371 aa
AA seq
DB search
CRANLVDLQKKLEELELDEQQKKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKV
QHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEH
MDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIK
LCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELSIGRYPIPP
PDAKELEAIFGRPMVDGAEGEPHTISPRPRPPGRPISGHGVDSRPAMAIFELLDYIVNEP
PPKLPSGVFTQDFQEFVNKCLIKNPAERADLKMLMNHGFIKRSEVEEVDFAGWLCKTLRL
NQPSTPTRTAV
NT seq
1116 nt
NT seq
+upstream
nt +downstream
nt
tgcagagcaaacttggtggacctccagaagaagctagaggaactagagcttgatgagcag
cagaagaagcggttagaagccttcctcacccaaaaggccaaggttggggagctcaaggat
gatgacttcgaacggatctcagagctgggagccgggaacggcggggtggtcaccaaggtc
cagcacagaccttcaggcctcatcatggcaagaaagctgatccacctggagatcaagcca
gccatccggaaccagatcatccgcgagctgcaggtgctgcatgagtgcaactccccgtac
attgtgggcttctacggggccttctacagcgacggggagatcagcatctgcatggagcac
atggatggtggctctctggaccaggtgttgaaagaagccaagagaattccagaagagatc
ctggggaaggtcagcattgcggttctgcggggcctggcgtatctccgggaaaagcaccag
atcatgcaccgagatgtgaaaccatctaacatcctcgtcaactccagaggggagatcaag
ctgtgcgattttggggtgagcgggcagctcatcgactccatggccaactccttcgtggga
actcgatcctatatgtctccggagcggctgcaaggcactcactactcggtgcagtcagac
atctggagcatgggcttgtccctggtggagctgtccattggaaggtaccccatccccccg
ccggatgccaaggagctggaggccatattcggccggcccatggtcgatggggcggaagga
gagcctcacaccatctcaccgcggccgagaccccccggacgccccatcagtggccacggg
gtggacagccgaccggctatggctatctttgaactgctggactacattgtgaacgagccg
cctcctaagctgcccagtggtgtcttcacccaggacttccaggagtttgtgaataaatgc
ctcattaagaacccagctgagcgagcagatctgaagatgctcatgaaccatggcttcatc
aaacggtctgaggtggaagaagtggattttgccggctggttgtgtaaaacgctgcgtctg
aaccagcccagcacgcccacacgcaccgccgtgtga
DBGET
integrated database retrieval system
