Myotis davidii (David's myotis): 102759978 Help Entry 102759978         CDS       T02992                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism myd  Myotis davidii (David's myotis) Pathway myd00230   Purine metabolism myd01100   Metabolic pathways myd01522   Endocrine resistance myd04015   Rap1 signaling pathway myd04020   Calcium signaling pathway myd04022   cGMP-PKG signaling pathway myd04024   cAMP signaling pathway myd04062   Chemokine signaling pathway myd04072   Phospholipase D signaling pathway myd04081   Hormone signaling myd04082   Neuroactive ligand signaling myd04114   Oocyte meiosis myd04211   Longevity regulating pathway myd04213   Longevity regulating pathway - multiple species myd04261   Adrenergic signaling in cardiomyocytes myd04270   Vascular smooth muscle contraction myd04371   Apelin signaling pathway myd04540   Gap junction myd04611   Platelet activation myd04713   Circadian entrainment myd04714   Thermogenesis myd04720   Long-term potentiation myd04723   Retrograde endocannabinoid signaling myd04724   Glutamatergic synapse myd04725   Cholinergic synapse myd04727   GABAergic synapse myd04750   Inflammatory mediator regulation of TRP channels myd04911   Insulin secretion myd04912   GnRH signaling pathway myd04913   Ovarian steroidogenesis myd04914   Progesterone-mediated oocyte maturation myd04915   Estrogen signaling pathway myd04916   Melanogenesis myd04918   Thyroid hormone synthesis myd04921   Oxytocin signaling pathway myd04923   Regulation of lipolysis in adipocytes myd04925   Aldosterone synthesis and secretion myd04926   Relaxin signaling pathway myd04927   Cortisol synthesis and secretion myd04928   Parathyroid hormone synthesis, secretion and action myd04934   Cushing syndrome myd04935   Growth hormone synthesis, secretion and action myd04970   Salivary secretion myd04971   Gastric acid secretion myd04972   Pancreatic secretion myd04976   Bile secretion myd05032   Morphine addiction myd05142   Chagas disease myd05146   Amoebiasis myd05163   Human cytomegalovirus infection myd05166   Human T-cell leukemia virus 1 infection myd05200   Pathways in cancer myd05207   Chemical carcinogenesis - receptor activation myd05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:myd00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102759978 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102759978 (ADCY1)    04371 Apelin signaling pathway     102759978 (ADCY1)    04020 Calcium signaling pathway     102759978 (ADCY1)    04072 Phospholipase D signaling pathway     102759978 (ADCY1)    04024 cAMP signaling pathway     102759978 (ADCY1)    04022 cGMP-PKG signaling pathway     102759978 (ADCY1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102759978 (ADCY1)    04081 Hormone signaling     102759978 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102759978 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     102759978 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102759978 (ADCY1)    04062 Chemokine signaling pathway     102759978 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     102759978 (ADCY1)    04923 Regulation of lipolysis in adipocytes     102759978 (ADCY1)    04912 GnRH signaling pathway     102759978 (ADCY1)    04913 Ovarian steroidogenesis     102759978 (ADCY1)    04915 Estrogen signaling pathway     102759978 (ADCY1)    04914 Progesterone-mediated oocyte maturation     102759978 (ADCY1)    04921 Oxytocin signaling pathway     102759978 (ADCY1)    04926 Relaxin signaling pathway     102759978 (ADCY1)    04935 Growth hormone synthesis, secretion and action     102759978 (ADCY1)    04918 Thyroid hormone synthesis     102759978 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     102759978 (ADCY1)    04916 Melanogenesis     102759978 (ADCY1)    04925 Aldosterone synthesis and secretion     102759978 (ADCY1)    04927 Cortisol synthesis and secretion     102759978 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102759978 (ADCY1)    04270 Vascular smooth muscle contraction     102759978 (ADCY1)   09154 Digestive system    04970 Salivary secretion     102759978 (ADCY1)    04971 Gastric acid secretion     102759978 (ADCY1)    04972 Pancreatic secretion     102759978 (ADCY1)    04976 Bile secretion     102759978 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     102759978 (ADCY1)    04727 GABAergic synapse     102759978 (ADCY1)    04725 Cholinergic synapse     102759978 (ADCY1)    04720 Long-term potentiation     102759978 (ADCY1)    04723 Retrograde endocannabinoid signaling     102759978 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102759978 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     102759978 (ADCY1)    04213 Longevity regulating pathway - multiple species     102759978 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     102759978 (ADCY1)    04714 Thermogenesis     102759978 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102759978 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     102759978 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102759978 (ADCY1)    05163 Human cytomegalovirus infection     102759978 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     102759978 (ADCY1)    05142 Chagas disease     102759978 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     102759978 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102759978 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102759978 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102759978 (ADCY1) Enzymes [BR:myd01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102759978 (ADCY1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Thyroglobulin_1 Motif Other DBs NCBI-GeneID:  102759978 NCBI-ProteinID:  XP_015423697 LinkDB All DBs Position Un AA seq 1009 aa AA seqDB search MCLRLPQSPEAAGCQGRSHPPAFMPRGTCLPAVLQSPVRCPALPGACDRGLWPAGHGALS CNRELGSPSGQSRSSGPGTFWKSPSFSDTGAVHVCRDGTGFGTAPRTRGRRGPAVAPPEL PVEGVGERWPSGAPAHALSSPLQLAANALLFLGVNMYGVCVRVLAERAQRRAFLRARTCI EDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIV GFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKADHAHC CVEMGLDMIDTITTLARVTRRLCPRSVAVLLLLVFCVCFLVACVLYLHVTRVQVRVLSLC LTWSRCVCVRVLSLXYAVAQGCVVGCLPWAWSSGPNGSLVVLPPGGLEAVLPAPPCESAP QALLCGLVGTLPLALFLRVSSLPKVVLLCVLSASYILVLELSASTRAVGGTTSGRSFEPV LAVLLFSCTLALHARQVDVKLRLDYLWASQARWALPAPGGWGGAEEPLGSGRQVGGPGWM RGGSTAGRRLTSATRPGSGDVTTAAAHLLARSFPIRAPAWPPWSTEEEDQVAGHSLHCLT VDLTPGRLPGASRLCTGCELANGGTRPPQAPSTAGPRPPTDPTSDPQDLYYQSYAQVGVM FASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDEVRCPRPGRHSQRPTPGGKWGTRQA DACYGWRSAPADPRLTSAPLSQAPACTVGVLSTPRGCRGCKSLKKMSHSRATERPRAEAA WWMWVPDPTGATGWSRPRQLAGGCPCPSALVSPECDARVVHVQAKRCVSAHLGALADFAL EMFHVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVPG RIQDPCQRELYDALAKLAQERTRCMVSLHGETGVCWCVYPWNGQRIAGSKDVIGDPNCDQ SPAVGREGPSPGSCRRRSESEDMPTPGTSVHLLVEARKAVPGTYVAGTQ NT seq 3030 nt NT seq  +upstreamnt  +downstreamnt atgtgcctgaggctgccccagtcacctgaggctgcaggctgccagggccgctcccaccca cctgcattcatgcccagggggacctgcctccctgctgtcctgcagtcacccgtcaggtgt cctgccctcccaggagcctgtgaccgtggcctgtggcctgcgggccacggtgctttgtcc tgtaatcgcgagctaggcagcccttctggtcagtccaggagcagcggccctggaaccttc tggaaaagcccgagtttctcggacacaggagccgtccacgtctgcagggacgggacaggg ttcggaacggctcccaggacccgcgggcgcagaggcccggccgtggcccctcccgagctg cccgtggagggggttggggagcgctggccaagcggggcccctgcccacgctctgtcctct cccctccagctcgccgccaacgccctgctcttcctgggcgtgaacatgtatggggtgtgc gtgagggtcctggcggagcgcgcccagcgcagggctttcctgcgggcgcgcacctgcatc gaggaccggctgcggctggaggacgagaacgagaagcaggagcggctgctcatgagcctc ctgccccggaacgttgccatggagatgaaggaggacttcctgaagccccccgagaggatc ttccacaagatttacatccagcggcatgacaacgtgagcatcctcttcgccgacatcgtg ggcttcacggggctggcgtcgcagtgcacggcccaggagctggtcaagctgctcaacgag ctctttggcaagttcgacgagctggccacggagaaccactgccggcgcatcaagatcctg ggggactgctactactgcgtgtcgggcctcacccagcccaaggccgaccacgcccactgc tgcgtggagatgggcctggacatgatcgacaccatcaccacgctggcccgagtgaccagg cgcctctgtcctaggagcgtggccgtcctgctgctgctggtgttctgcgtctgcttcctg gtggcctgtgtcctgtacctgcatgtcacccgggtccaggtgcgtgtcctgtctctgtgc ctcacctggtccaggtgcgtgtgtgtacgtgtcctgtctctnnnntacgcggtggcccaa ggctgtgtggtgggctgcctgccctgggcctggagctccggtcccaacgggtccctggtg gtgctgccgcccggcggcctggaagccgtgctgcccgccccgccctgcgagtccgcgccc caggccctgctctgcggcctggtgggcaccctcccgctcgccctcttcctgcgggtctcc tctttgcccaaagtggtcctgctgtgcgtgctcagcgcgtcctacatcctggtcctggag ctcagcgcctccacccgggctgtggggggcaccacctccgggcgcagcttcgagcccgtc ctggccgtcctgctgttctcctgcacgctggccctgcacgcccggcaggtggacgtcaag ctgcggctggactacctctgggcctcgcaggcaagatgggcccttcctgctcccgggggg tgggggggcgcggaggagccccttgggagcgggcgtcaggtgggcggtcctggctggatg aggggaggcagcacagcaggccgccgcctcacatcagcaacgcggccgggcagcggggac gtcaccacggccgcagctcaccttctcgcgaggagtttccccatccgagcgcccgcgtgg ccgccctggagcaccgaggaggaggaccaggtggcgggacacagcctgcactgcctgacg gtggacctgacgccgggacgactcccaggagccagcaggctctgcactggctgtgagctg gccaatggggggacccggccccctcaagccccttccacagcagggccccggccgcccact gacccgacctccgacccccaggacctgtactaccagtcgtacgcccaggtgggcgtcatg ttcgcgtccatccccaacttcaacgacttctacatcgagctggacggcaacaacatgggg gtggagtgcctgcggctgctcaatgagatcatcgccgacttcgacgaggtgaggtgcccg cggccggggcgtcactcacagagacccacacccggagggaaatgggggacgcgccaggcg gacgcctgttacggttggcggtcagcgcccgcagacccccgactgacctcggcgcctctg tctcaggcccctgcctgcacagtgggggtgctgagcacccccaggggctgcaggggctgc aaatccctgaagaagatgagccattcccgggccacggaacggccccgcgcggaggctgcc tggtggatgtgggtccccgatcccactggggctacaggctggtcccgcccccggcagctg gccggcgggtgcccctgcccctctgcccttgtttcccctgaatgtgacgcccgtgtcgtc cacgtgcaggctaagaggtgcgtctccgcccacctgggcgcgctggccgacttcgccctt gagatgttccatgtgctggacgagatcaactaccagtcctacaatgacttcgtgctccgc gtgggcatcaacgtggggccggtggtggccggtgtgatcggggcgcgccgcccgcagtac gacatctggggcaacaccgtcaatgtggccagtcggatggacagcacgggcgtcccgggc aggatccaggacccctgccagcgagaactctacgatgcgctggccaagctggcccaggag cggacgaggtgcatggtgtccctgcatggagagacaggggtctgctggtgcgtgtacccc tggaacgggcagaggatcgcggggtccaaggatgtcatcggggaccccaactgcgatcag agtccggccgttgggcgagaaggcccctctccaggcagctgccgccggaggagcgagtct gaggacatgcccaccccgggcacaagcgtccacctgctggtagaggcccggaaggcggtg cctggcacctacgtggccgggacccagtga

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