KEGG   Myotis davidii (David's myotis): 102764895
Entry
102764895         CDS       T02992                                 
Symbol
LCK
Name
(RefSeq) LCK proto-oncogene, Src family tyrosine kinase
  KO
K05856  lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
Organism
myd  Myotis davidii (David's myotis)
Pathway
myd04064  NF-kappa B signaling pathway
myd04380  Osteoclast differentiation
myd04650  Natural killer cell mediated cytotoxicity
myd04658  Th1 and Th2 cell differentiation
myd04659  Th17 cell differentiation
myd04660  T cell receptor signaling pathway
myd05135  Yersinia infection
myd05166  Human T-cell leukemia virus 1 infection
myd05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
myd05340  Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:myd00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    102764895 (LCK)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    102764895 (LCK)
   04660 T cell receptor signaling pathway
    102764895 (LCK)
   04658 Th1 and Th2 cell differentiation
    102764895 (LCK)
   04659 Th17 cell differentiation
    102764895 (LCK)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102764895 (LCK)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102764895 (LCK)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102764895 (LCK)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    102764895 (LCK)
  09163 Immune disease
   05340 Primary immunodeficiency
    102764895 (LCK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:myd01001]
    102764895 (LCK)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:myd03036]
    102764895 (LCK)
Enzymes [BR:myd01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     102764895 (LCK)
Protein kinases [BR:myd01001]
 Non-receptor tyrosine kinases
  SRC family
   102764895 (LCK)
Chromosome and associated proteins [BR:myd03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    102764895 (LCK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 ABC1 Haspin_kinase SH3_16 MDHAR3-like_C Kdo SH3_3
Other DBs
NCBI-GeneID: 102764895
NCBI-ProteinID: XP_006777444
LinkDB
Position
Un
AA seq 519 aa
MGCGCSSNPEDDWMENIDVCENCHYPIVPLDGKATLPIRNGSEVRDPLVTYQDTNPPASP
LQDNLVIALHSYEPSHDGDLGFEKGEQLRVLEQNGEWWKAQSLTTGQEGFIPFNFVAKAN
SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIREXVKNHLMFAYLFFYSGSFSLSVRDF
DQNQGEVVKHYKIRNLDKGGFYISPRITFPGLQELVRHYTNTPDGLCTRLSRPCQTQKPQ
KPWWEDEWEVPRETLKLVERLGAGQFGXXXXGYYNGHTKVAVKSLKQGSMSPDAFLAEAN
LMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPAGIKLTINKLLDMAAQIAE
GMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPE
AINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELY
HLMMLCWKEHPEDRPTFDYLRSVLDDFFTATEGQYQPQP
NT seq 1560 nt   +upstreamnt  +downstreamnt
atgggctgtggctgcagctcaaaccctgaagatgactggatggaaaacatcgatgtgtgt
gagaactgccattaccccatagtcccactggatggcaaggccacgctgcccatccggaat
ggctctgaggtgcgggatccactggtcacctaccaggacaccaaccccccggcttctcca
ctgcaagacaacctggtcatcgccctgcacagctatgagccctctcacgatggggacctg
ggattcgaaaagggtgaacagcttcgtgtcctggagcagaacggcgagtggtggaaggcg
cagtctctgaccaccggccaggagggtttcatccccttcaacttcgtggccaaagcgaac
agcctggagcccgaaccctggttcttcaaaaacctgagccgcaaggatgctgagcggcag
ctcctggcccccgggaacacgcacggctccttcctgatccgggagtaagttaaaaatcat
ttgatgttcgcttacctattcttttattcaggatcgttttccctgtccgttcgggacttc
gaccagaaccaaggagaggtggtgaaacattacaagatccgcaacctggacaaaggaggc
ttctacatctccccccgcatcacttttcccggcctgcaggagctggtccgccattacacc
aacactccggacgggctatgcacgcggttgagccgcccctgccagacccagaagccgcag
aagccgtggtgggaggacgagtgggaggttcccagggagacgctgaagctggtggagcgg
ctgggggccggccagttcgggnnnnnnnnnncagggtactacaacgggcacacgaaggtg
gccgtgaagagcctgaagcagggcagcatgtcccccgacgccttcctggccgaggccaac
ctcatgaagcagttgcagcatcagcggctggtccggctctacgcggtggtcacccaggag
cccatctacatcatcacggaatacatggagaatgggagcctggtggattttctcaagacc
cctgcaggcatcaagctgaccatcaacaaactcttggatatggcagcccaaattgcagag
ggcatggcgtttattgaagagcgcaattacatccaccgtgacctgagggccgccaacatc
ctggtgtctgacaccctgagctgcaagatcgcagactttggcctagcacgcctcattgag
gacaacgagtacacagccagggagggggccaagtttcccattaagtggacagcgccagaa
gccattaactatgggaccttcaccatcaagtcggacgtgtggtctttcgggattctgctg
acagagattgtcacccacggtcgcatcccttacccagggatgaccaatcctgaggtgatt
cagaacctggagcgaggttaccgcatggtgagacctgacaactgtccagaggagctgtac
cacctcatgatgctgtgttggaaggagcacccagaggaccggcccacctttgactacctg
cgcagcgtgctggacgacttcttcacggccacggagggccagtaccagccccagccctga

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