KEGG PATHWAY: mye00633

PATHWAY: mye00633

Entry

mye00633                    Pathway

Name

Nitrotoluene degradation - Mycobacterium sp. EPa45

Class

Metabolism; Xenobiotics biodegradation and metabolism

Pathway map

mye00633

Nitrotoluene degradation

Other DBs

UMBBD:

tnt tnt2 dnt

GO:

0046260

Organism

Mycobacterium sp. EPa45 [GN:mye]

Gene

AB431_24860

1,2-oxophytodienoate reductase [KO:K10680] [EC:1.-.-.-]

AB431_09790

hydrogenase [KO:K06281] [EC:1.12.99.6]

AB431_09795

hydrogenase expression protein HypE [KO:K06282] [EC:1.12.99.6]

Compound

C01468

4-Cresol

C06002

(S)-Methylmalonate semialdehyde

C11006

2,4-Dinitrotoluene

C14401

2,4-Diaminotoluene

C16391

Trinitrotoluene

C16392

4-Hydroxylamino-2,6-dinitrotoluene

C16393

2-Hydroxylamino-4,6-dinitrotoluene

C16394

4-Amino-2,6-dinitrotoluene

C16395

2-Amino-4,6-dinitrotoluene

C16396

2,4-Diamino-6-nitrotoluene

C16397

2,6-Diamino-4-nitrotoluene

C16398

2-Amino-4-nitrotoluene

C16399

2,4-Diamino-6-hydroxylaminotoluene

C16400

2,4,6-Triaminotoluene

C16401

2,4,6-Trihydroxytoluene

C16402

2,4-Dihydroxylamino-6-nitrotoluene

C16403

4-Amino-2-hydroxylamino-6-nitrotoluene

C16411

4,4',6,6'-Tetranitro-2,2'-azoxytoluene

C16412

2,4',6,6'-Tetranitro-2',4-azoxytoluene

C16413

2,2',6,6'-Tetranitro-4,4'-azoxytoluene

C16414

2-Amino-5-hydroxyl-4-hydroxylamino-6-nitrotoluene

C16420

4-Acetamido-2-amino-6-nitrotoluene

C18315

4-Methyl-5-nitrocatechol

C18316

2-Hydroxy-5-methylquinone

C18317

2,4,5-Trihydroxytoluene

C18318

cis,cis-2,4-Dihydroxy-5-methyl-6-oxo-2,4-hexadienoate

C18320

4-Amino-2-nitrotoluene

Reference

Authors

Esteve-Nunez A, Ramos JL.

Title

Metabolism of 2,4,6-trinitrotoluene by Pseudomonas sp. JLR11.

Journal

Environ Sci Tech 32:3802-3808 (1998)
DOI:10.1021/es9803308

Reference

PMID:8534088

Authors

Gilcrease PC, Murphy VG.

Title

Bioconversion of 2,4-diamino-6-nitrotoluene to a novel metabolite under anoxic and aerobic conditions.

Journal

Appl Environ Microbiol 61:4209-14 (1995)
DOI:10.1128/AEM.61.12.4209-4214.1995

Reference

PMID:11527999

Authors

Esteve-Nunez A, Caballero A, Ramos JL.

Title

Biological degradation of 2,4,6-trinitrotoluene.

Journal

Microbiol Mol Biol Rev 65:335-52, table of contents (2001)
DOI:10.1128/MMBR.65.3.335-352.2001

Reference

PMID:14751225

Authors

Fleischmann TJ, Walker KC, Spain JC, Hughes JB, Morrie Craig A.

Title

Anaerobic transformation of 2,4,6-TNT by bovine ruminal microbes.

Journal

Biochem Biophys Res Commun 314:957-63 (2004)
DOI:10.1016/j.bbrc.2003.12.193

Reference

PMID:14753774

Authors

Borch T, Gerlach R.

Title

Use of reversed-phase high-performance liquid chromatography-diode array detection for complete separation of 2,4,6-trinitrotoluene metabolites and EPA Method 8330 explosives: influence of temperature and an ion-pair reagent.

Journal

J Chromatogr A 1022:83-94 (2004)
DOI:10.1016/j.chroma.2003.09.067

Reference

PMID:15490158

Authors

Yin H, Wood TK, Smets BF.

Title

Reductive transformation of TNT by Escherichia coli: pathway description.

Journal

Appl Microbiol Biotechnol 67:397-404 (2005)
DOI:10.1007/s00253-004-1736-x

Reference

PMID:16187099

Authors

Kutty R, Bennett GN.

Title

Biochemical characterization of trinitrotoluene transforming oxygen-insensitive nitroreductases from Clostridium acetobutylicum ATCC 824.

Journal

Arch Microbiol 184:158-67 (2005)
DOI:10.1007/s00203-005-0036-x

Reference

PMID:16535610

Authors

Fiorella PD, Spain JC.

Title

Transformation of 2,4,6-Trinitrotoluene by Pseudomonas pseudoalcaligenes JS52.

Journal

Appl Environ Microbiol 63:2007-2015 (1997)
DOI:10.1128/AEM.63.5.2007-2015.1997

Reference

PMID:17504490

Authors

Gonzalez-Perez MM, van Dillewijn P, Wittich RM, Ramos JL.

Title

Escherichia coli has multiple enzymes that attack TNT and release nitrogen for growth.

Journal

Environ Microbiol 9:1535-40 (2007)
DOI:10.1111/j.1462-2920.2007.01272.x

Reference

PMID:16535348

Authors

Noguera DR, Freedman DL

Title

Reduction and Acetylation of 2,4-Dinitrotoluene by a Pseudomonas aeruginosa Strain.

Journal

Appl Environ Microbiol 62:2257-63 (1996)
DOI:10.1128/AEM.62.7.2257-2263.1996

Reference

PMID:9922262

Authors

Haigler BE, Johnson GR, Suen WC, Spain JC

Title

Biochemical and genetic evidence for meta-ring cleavage of 2,4, 5-trihydroxytoluene in Burkholderia sp. strain DNT.

Journal

J Bacteriol 181:965-72 (1999)
DOI:10.1128/JB.181.3.965-972.1999

Reference

PMID:12107140

Authors

Johnson GR, Jain RK, Spain JC

Title

Origins of the 2,4-dinitrotoluene pathway.

Journal

J Bacteriol 184:4219-32 (2002)
DOI:10.1128/JB.184.15.4219-4232.2002

Related
pathway

mye00280

Valine, leucine and isoleucine degradation

mye00623

Toluene degradation

KO pathway

ko00633

LinkDB

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