Mycobacterium sp. EPa45: AB431_22955
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Entry
AB431_22955 CDS
T03960
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mye
Mycobacterium sp. EPa45
Pathway
mye00020
Citrate cycle (TCA cycle)
mye00630
Glyoxylate and dicarboxylate metabolism
mye00785
Lipoic acid metabolism
mye01100
Metabolic pathways
mye01110
Biosynthesis of secondary metabolites
mye01120
Microbial metabolism in diverse environments
mye01200
Carbon metabolism
mye01210
2-Oxocarboxylic acid metabolism
Module
mye_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mye_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mye00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
AB431_22955 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
AB431_22955 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AB431_22955 (kgd)
Enzymes [BR:
mye01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
AB431_22955 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
AB431_22955 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
AB431_22955 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
AB431_22955 (kgd)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AKK29053
LinkDB
All DBs
Position
4869598..4873356
Genome browser
AA seq
1252 aa
AA seq
DB search
MSSTSSPFGQNEWLVEEMYRKFREDPSSVDSSWHEFLVDYNPEPTTDSSAGGNGQPARTA
APVSPPEPAPAPPPAKPAPAKTAPAGNGAPASAPAKQAPAKPAPAKEAPAKEPAPKAAPA
SSSDNGDETQVLRGAAAAVVRNMNSSLEIPTATSVRAIPAKLMIDNRIVVNNHLKRTRGG
KVSFTHLLGYAIVQAVKKFPNMNRHYAEIDGKPNAVTPAHTNLGLAIDLQGKDGKRSLVV
AAIKNCETMRFGQFIAAYEDIVRRARDGKLTAEDFAGVTISLTNPGTIGTVHSVPRLMSG
QGAIVGAGAMEYPAEFQGASEERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTIHELL
LSDDFFDEIFFELGIPYEPVRWRTDNPDSIVDKNARVIELIAAYRNRGHLMADIDPLRLD
KTRFRSHPDLDVNTHGLTLWDLDRVFKVDGFAGKEFKKLRDVLGLLRDAYCRHIGVEYTH
ILEPEQQKWLQERIEVKHEGPTVAQQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAET
VIPMMDAAIDQAAEHALDEVVIGMPHRGRLNVLANIVGKPYSQIFSEFEGNLNPSQAHGS
GDVKYHLGARGDYIQMFGDNDIEVSLTANPSHLEAVDPVMEGIVRAKQDLLDKGTGEDGF
TVMPMMLHGDAAFAGQGVVAETLNLALLRGYRTGGTIHIIVNNQIGFTTSPQDSRSSEYC
TDVAKMVGAPIFHVNGDDPEACVWVARLAVDFRQKFKKDVIIDMLCYRRRGHNEGDDPSM
TQPYMYDVIDTKRGVRKTYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRDLEKHEV
EPSESVEEDQMIPRGMTTAVDKSLLARIGDAHLAFPENFSVHPRVKPVLEKRREMAYEGK
VDWAFAELLALGTFLAEGKLIRLSGQDTRRGTFTQRHSVIIDRKTGAEFTPLDLLTVNPD
GTPTGGKLLVYDSALSEYAAVGFEYGYSVGNPDALVLWEAQFGDFVNGAQSIIDEFISSG
EAKWGQLSDVVLLLPHGHEGQGPDHTSGRIERFLQLWAEGSMTIALPSTPANYFHLLRRH
GLDGVHRPLIVFTPKSMLRNKAAVSDLRDFTEQKFRSIMEEPTYTDGDGDRNKVSRILLT
SGKIYYELVARKDKDKRDDVAIVRVEQLAPLPKRRLSNTLDSYPNAKEFFWVQEEPANQG
AWPTFGLTLPELLPEKLTGIKRISRRAMSAPSSGSSKVHAVEQQEIIDEAFG
NT seq
3759 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagtactagttcaccattcggacagaacgaatggctggtcgaggagatgtaccgc
aagttccgcgaggatccctcctcggtcgactcgagttggcatgagttcctggtcgactac
aacccggagccgacgaccgactccagcgccggcgggaacggccagccggccaggaccgcc
gcaccggtgtccccgccggaacccgcaccggctccgccgccggccaagccggcccccgcc
aagaccgccccggcgggcaatggcgctccggcgtcagcccccgccaagcaggcccccgcc
aaaccggccccggccaaagaggccccggccaaggagcccgcacccaaggcagcaccggcg
tcgtcgtcggacaacggtgatgagacccaggtgttgcgtggcgcggcggcggccgtcgtc
cgcaacatgaactcgtcgctggagatcccgaccgcgaccagcgtgcgggccatcccggcg
aagctgatgatcgacaaccgcatcgtcgtcaacaaccacctcaagcgcacccgcggcggc
aaagtctccttcacccacctgctcggctacgcgatcgtgcaggcggtcaagaagttcccg
aacatgaaccggcactacgcggagatcgacggcaagcccaacgccgtcacccccgcccac
accaatctgggcctggcgatcgacttgcagggcaaggacggcaaacgctcattggtcgtg
gccgcgatcaagaactgcgagaccatgcggttcggccagttcatcgccgcctacgaggac
atcgtccggcgagcccgcgacggcaagctcaccgccgaggatttcgccggggtgacgatc
tcgctgaccaaccccggcaccatcggcaccgtgcactcggtgccccgactgatgtccggc
cagggcgcaatcgtcggcgccggcgcgatggagtacccggcggagttccagggcgccagc
gaggagcgcatcgccgagctcggcatcggcaagctgatcacgctgacgtcgacctacgac
caccgcatcattcagggcgcggagtccggcgacttcctgcggaccatccacgagctgctg
ctctccgacgatttctttgacgagatcttcttcgagctgggcatcccctacgagccggtc
cgctggcgcaccgacaaccccgattcgatcgtcgacaagaacgcccgggtgatcgagctg
atcgccgcgtaccgcaaccgcgggcacctgatggcggacatcgacccgctgcgcctggac
aagacccgcttccgcagccaccccgacctcgacgtcaacacccacggcctgaccctgtgg
gacctggaccgggtgttcaaggtcgacggcttcgcgggcaaggagttcaagaagctgcgc
gacgtgctgggtctgctgcgcgacgcgtactgccgccacatcggcgtggagtacacccac
atcctcgaacccgagcagcagaagtggctgcaggagcgcatcgaggtcaagcacgagggc
ccgaccgtcgcccagcagaagtacatcctgtccaagctcaacgccgcggaagccttcgag
acgttcctgcagaccaaatacgttgggcagaagcgcttttcgctggagggcgcggagacc
gtcatcccgatgatggatgccgcgatcgaccaggcggccgagcacgccctcgacgaggtc
gtgatcggcatgccgcaccgcggccggctcaacgtgctggccaacatcgtcggcaagccg
tattcgcagatcttcagcgagttcgagggcaacctgaacccgtcgcaggcgcatggctcc
ggcgacgtcaagtaccacctcggcgcccggggcgactacatccagatgttcggtgacaac
gacatcgaggtctcgctgaccgccaacccgtcgcacctcgaagccgtcgatccggtgatg
gaaggcatcgttcgggccaaacaggatctgctggacaagggaaccggtgaggacggcttc
accgtcatgccgatgatgctgcacggcgatgcggccttcgccggtcagggtgtggtggcc
gagacgctgaacctcgcgctgctgcgcgggtaccgcaccggcggcacgatccacatcatc
gtcaacaaccagatcggcttcaccacctcgccgcaggactcgcgcagctcggagtactgc
accgacgtcgcaaagatggtgggagcgcccatcttccacgtcaacggcgacgacccggag
gcgtgcgtctgggtggcgcggctggcggtggacttccggcagaagttcaagaaggacgtc
atcatcgacatgctgtgctaccgcaggcgcgggcacaacgaaggtgacgacccgtcgatg
acccagccctacatgtacgacgtcatcgacaccaagcgcggcgtgcgcaagacctacacc
gaagccctgatcggccgtggcgacatctcgatgaaagaggccgaggacgcgctgcgcgac
taccagggccagctggagcgggtgttcaacgaagtccgcgacctcgagaaacacgaggtc
gaacccagcgagtcggtcgaggaagaccagatgatcccgcgcggcatgaccaccgcggtg
gacaagtcgctgctggcccgcatcggcgatgcgcatctggcgttccccgagaacttcagc
gtgcacccccgcgtcaagccggtgctggagaagcgccgcgagatggcctacgagggcaaa
gtcgactgggcgttcgccgaattgctggcgctcggaacgtttttggccgagggtaagctg
atccggttgtccggtcaggacactcgccgcggcacgttcacccagcgccactcggtgatc
atcgaccgtaagaccggcgcggagttcaccccgctggacctgttgaccgtcaatccggac
ggcacgccgaccggcggtaagctgctggtgtacgactcggcactgtcggagtacgccgcc
gtcggcttcgaatacggctattcggtcggcaacccggacgcactggtgttgtgggaggcg
cagttcggcgacttcgtcaatggcgcgcagtcgatcatcgacgagttcatcagttccggt
gaggccaagtggggtcagctctccgatgtggtgctgctgctcccccacggccacgagggc
caggggcccgaccacacctccggccgcatcgagcgcttcctgcagctgtgggccgagggt
tcgatgacgatcgcgctgccgtcgaccccggcaaactacttccacctgttgcgccggcac
ggcctcgacggggtgcaccgcccgctgatcgtcttcacgccgaaatcgatgctgcgcaac
aaggctgccgtcagcgatctgcgggacttcaccgagcagaagttccggtcgatcatggaa
gaaccgacctacaccgacggcgacggcgaccgcaacaaggtcagccgcatcctgttgacc
agcggcaagatctactacgaactggtggcgcgcaaggacaaggacaagcgcgacgacgtc
gcgatcgtccgggtcgagcagctggcgccgctgcccaagcggcggctgagcaacaccctg
gattcgtatccgaatgccaaggagttcttctgggttcaggaggagccggccaaccagggt
gcgtggccgacgttcggcctgacgttgccagagttgttgccggagaagctgaccgggatc
aagcggatctcgcggcgcgccatgtcggcgccgtcgtccggctcgtcgaaggtgcacgcc
gtcgagcagcaggagatcatcgacgaggcattcggctag
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