Mycolicibacterium sp. HK-90: QU592_19250
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Entry
QU592_19250 CDS
T11081
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
myh Mycolicibacterium sp. HK-90
Pathway
myh00010
Glycolysis / Gluconeogenesis
myh00020
Citrate cycle (TCA cycle)
myh00620
Pyruvate metabolism
myh00785
Lipoic acid metabolism
myh01100
Metabolic pathways
myh01110
Biosynthesis of secondary metabolites
myh01120
Microbial metabolism in diverse environments
myh01200
Carbon metabolism
myh01210
2-Oxocarboxylic acid metabolism
Module
myh_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
myh00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
QU592_19250 (aceE)
00020 Citrate cycle (TCA cycle)
QU592_19250 (aceE)
00620 Pyruvate metabolism
QU592_19250 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
QU592_19250 (aceE)
Enzymes [BR:
myh01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
QU592_19250 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
WKG01404
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Position
3983826..3986615
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AA seq
929 aa
AA seq
DB search
MTTEFVRQDLAQNSSTAAEPDRVRVIREGVASYLPDIDTDETSEWLESFDELLERSGPAR
ARYLMLRLLERSREKRVAIPALTSTDYVNTIPTELEPWFPGDEDVERRFRAWIRWNAAIM
VHRAQRPGVGVGGHISTYASSASLYEVGFNHFFRGKSHPGGGDQVFIQGHASPGIYARAF
LEGRLTTDQLDGFRQEHSHKGGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHY
LHDRGLKDTSDQHVWAFLGDGEMDEPESRGLIQVAANEALDNLTFVVNCNLQRLDGPVRG
NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDGDYQTYKANDG
AYVRDHFFGRDPRTKALVEPMTDQEIWNLKRGGHDYRKVYAAYRAAMEHKGQPTVILAKT
IKGYTLGSHFEGRNATHQMKKLALQDLKDFRDVTRVPISDEQLEQDPYLPPYYHPGPEAP
EIRYLLDRRRALGGFLPSRRTKSTPLPLPGSDTYKALKKGSGQQSVATTMATVRTFKELL
RDKNIGPRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYTSVDSELMLAYKESEVGQILH
EGINEAGSTSSFTAVGTSYSTHNEPMIPIYIFYSMFGFQRTGDGLWAAADQMAKGFVLGA
TAGRTTLTGEGLQHADGHSLLLASTNPAAVTYDPAFAYEIAHIIESGLQRMYGEHPENVF
FYITIYNEPYVQPAEPADLDTEALLRGMYRYRRAAEPRAGTAQILASGVSMPEALRAADM
LAEEWDVAADVWSVTSWGELNREGVEIERHRLRHPDQPARTPHVTNVLADAAGPVVAVSD
WMRAVPEQIRPWVPGTYITLGTDGFGFSDTRPAARRYFNTDAESVVVAVLEGLARDGEID
PSVAVAAAKQYKIDDVFAAAVSFVDTGSA
NT seq
2790 nt
NT seq
+upstream
nt +downstream
nt
ttgaccaccgagttcgtgcgccaggatctggcccaaaactcctctaccgcagcagaaccc
gaccgggtccgggtgatccgggagggggtcgcgtcatacctgcccgatatcgacaccgac
gagacgagcgaatggctcgaatcgttcgatgagctactcgaacgatccggcccggctcgg
gcacggtatctgatgctgcgattgctggaacgctcccgcgagaagcgggtggccattccg
gcactgacgtccaccgactacgtcaacaccatcccgaccgaactcgagccgtggttcccc
ggcgacgaggacgtcgagcgacgcttccgcgcctggatccgctggaacgccgcgatcatg
gtgcaccgcgcccagcggcccggagtcggtgtgggcggccacatttcgacgtacgcctcg
tcggcttcgctgtacgaggtcgggttcaaccacttcttccgcggcaaatcccaccccggc
ggcggcgaccaggtgttcatccaaggccacgcgtcccccggcatctacgcccgcgcgttc
ctggaaggccggctgacgaccgaccaactggatggtttccgccaggagcactcgcacaag
ggcggcggcctgccgtcgtacccgcacccgcggctcatgccggacttctgggaattcccg
acggtgtcgatgggcctgggcccgatgaacgccatctaccaggcccggttcaaccactac
ctgcacgaccgtggcctcaaggacacctccgatcagcacgtgtgggcgttcctcggtgac
ggcgagatggacgagcccgagagccgcggcctgatccaggtggccgcgaacgaggcactg
gacaacctgaccttcgtggtcaactgcaacctgcagcgcctcgacggcccggtgcgcggc
aacggcaagatcatccaggagctggagtcgttcttccgcggcgccggctggaacgtcatc
aaggtggtctggggccgcgagtgggacgccctgctgcacgccgaccgcgacggtgcgctg
gtcaatctgatgaacacgacgcccgacggcgactaccagacgtacaaggccaacgacggc
gcctacgtgcgcgaccacttcttcgggcgcgatccgcgcaccaaggcactggtcgagccg
atgacggaccaggagatctggaacctcaagcgcggcggccacgattaccgcaaggtgtac
gccgcctaccgcgccgcgatggagcacaagggtcagccgacggtgatcctggccaagacc
atcaagggctacacgctgggcagccacttcgagggccgcaacgccacccaccagatgaaa
aagcttgcgctgcaagacctgaaggacttccgggatgtcacccgggtgccgatcagcgat
gagcagctggagcaggacccctatctgccgccgtactaccacccggggcccgaggcgccg
gagatccggtatctgctggatcggcggcgtgccctcggcgggttcctgccctcgcgtcgc
accaagagcacgccgctgccgctgcccggttccgacacctacaaggccctgaagaagggg
tccggccagcagtcggtggccaccaccatggccactgtccgcaccttcaaggaactgttg
cgggacaagaacatcgggccgcggatcgtgccgatcatccccgacgaggcccggacgttc
ggcatggactcctggttcccgagcctgaagatctacaaccgcaacgggcagctgtacacc
tcggtggactccgaactgatgttggcctacaaggaatccgaggtcggccagatcctgcac
gagggcatcaacgaagcggggtcgacctcgtcgttcaccgcggtcggcacgtcctactcg
acgcacaacgagccgatgatcccgatctacatcttctattcgatgttcgggttccagcgc
accggtgacggcctgtgggccgcggccgatcagatggcgaagggcttcgtgctcggcgcg
accgccggccgcaccaccctgaccggtgaggggctgcagcacgccgacggccattcgctg
ttgctcgcatcgaccaatccggccgcggtgacctatgacccggcgttcgcctacgagatc
gcccacatcatcgagagcggtctgcagcggatgtacggcgagcatccggagaacgtgttc
ttctacatcaccatctacaacgagccgtacgtgcagccggccgagccggccgatctggac
accgaggccctgttgcgcgggatgtaccgctaccggcgggcggccgagccacgcgccggc
acggcccagatcctggcctcgggcgtgtcgatgccggaagcgctgcgagcggccgacatg
ctggccgaggagtgggacgtggccgccgacgtgtggtccgtgaccagttggggcgagctc
aaccgcgagggcgtcgagatcgagcgccaccggctgcggcaccccgaccaaccggcccgc
accccgcacgtgaccaacgtcctggccgatgcggccggcccggtggtcgcggtgtcggac
tggatgcgtgcggtgcccgagcagatccgcccctgggtcccgggtacctacatcacgctc
ggcaccgatggcttcggcttctccgacacccggccggccgctcgccgctacttcaacacc
gacgccgagtcggtcgtggtggcggtgttggagggcttggcccgcgacggcgagatcgat
ccgtcggtggccgtcgcggcggccaagcagtacaagatcgacgacgtgttcgcggcggcg
gtctccttcgtcgacaccggcagcgcctag
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