Myotis yumanensis (Yuma myotis): 139006078
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Entry
139006078 CDS
T10762
Symbol
IRS2
Name
(RefSeq) insulin receptor substrate 2 isoform X1
KO
K07187
insulin receptor substrate 2
Organism
myum Myotis yumanensis (Yuma myotis)
Pathway
myum04022
cGMP-PKG signaling pathway
myum04068
FoxO signaling pathway
myum04081
Hormone signaling
myum04140
Autophagy - animal
myum04152
AMPK signaling pathway
myum04211
Longevity regulating pathway
myum04213
Longevity regulating pathway - multiple species
myum04910
Insulin signaling pathway
myum04920
Adipocytokine signaling pathway
myum04923
Regulation of lipolysis in adipocytes
myum04930
Type II diabetes mellitus
myum04931
Insulin resistance
myum04932
Non-alcoholic fatty liver disease
myum04935
Growth hormone synthesis, secretion and action
myum05010
Alzheimer disease
myum05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
myum00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
139006078 (IRS2)
04022 cGMP-PKG signaling pathway
139006078 (IRS2)
04152 AMPK signaling pathway
139006078 (IRS2)
09133 Signaling molecules and interaction
04081 Hormone signaling
139006078 (IRS2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
139006078 (IRS2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
139006078 (IRS2)
04923 Regulation of lipolysis in adipocytes
139006078 (IRS2)
04920 Adipocytokine signaling pathway
139006078 (IRS2)
04935 Growth hormone synthesis, secretion and action
139006078 (IRS2)
09149 Aging
04211 Longevity regulating pathway
139006078 (IRS2)
04213 Longevity regulating pathway - multiple species
139006078 (IRS2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
139006078 (IRS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
139006078 (IRS2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
139006078 (IRS2)
04932 Non-alcoholic fatty liver disease
139006078 (IRS2)
04931 Insulin resistance
139006078 (IRS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
IRS
PH
PH_11
MEKK4_N
Mcp5_PH
Motif
Other DBs
NCBI-GeneID:
139006078
NCBI-ProteinID:
XP_070264702
LinkDB
All DBs
Position
Unknown
AA seq
1406 aa
AA seq
DB search
MASPPLHGPPAPAGGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGASSDEA
TAGGGPAPQPPRLEYYESEKKWRSKAGAPKRVISLDCCLNINKRADAKHKYLIALYTKDE
YFAVAAENEQEQEGWYRALTDLVSEGRAGAGDSAPTAIHAGSCSASLPGTLGGSAGSDDS
YGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLM
NIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPR
SKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRTRTDSLAATPPATKCNSCRVRT
ASEGDGGAAAGTGAAGGRPVSVAGSPLSPGPVRTPLSRSHTLSAGCGNRASKVTLAPAGG
ALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPLPPGPHPHLQHPLHHHAGQRPSS
GSASASGSPSDPGFMSLDEYGSSPGDVRAFCSHRSNTPESIAETPPAKDGSGSELYGYMT
MDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRAVPQPSSASLDEYTLMRAT
FSGSSGRLCPSCPTSSPRVAYHPYPEDYGDIEIGSHRSSSSNLGTDDGYMPMTPGAALMG
GGSGSCKSDDYMPMSPTSVSAPKQIVHPRVAAAALPPTGPAALAPTNVAGRAFPVNRASY
KASSPAESSPEDSGYMRMWCGTKLPTESTDSKQLPNGDYLNMSPSDAGTAGTPPDFFTAA
LQGAGEMLRSVPGYCYSSLPRSYKAPYTCNGDNDQYVLMSSPVGRILEEERLEPQASVGT
THPASSVVAGVGGGSHAQPPHSVVPSAGRQSGSGSGSGRPEGFLSQRCRAVRPTRLSLEG
LQTLPSMHECPLPPEPKSPGEYINIDFGEAGARLSPPAPPMMLASAASSSSLLSASSPAS
SLGSGTPGTSSDSRQRSPLSDYMNLDFNSPKSPKADTQSGDPVGSLDGLLSPEASSGYPP
LPPRPAAPSSSSQLQPPPPPPPGELYRLPPAPTSQGPSAASSSSSETGDNGDYTEMAFGV
AATPPQPIVAPPKPDGARVTSPTSGMKRLSLMDHVSGVEAFLQAGQPPDPHRGAKVIRAD
PQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGSGSGVLGGGDE
PPASPRQPQPPLPQQARPWTPSQPGGLVGCPGGSGSPMRRETSAGFQNGLNYIAIDVRDE
PGLLPSPQQHPHLHPHPQPGDKSAWGRTRSLGGLISTVGAGSTGGVCGGPGPGALPSNTY
ASIDFLSHHLKEATIVKDIHDLSRRAPFSSCAEEASWPAAAPSTHSASCSESLLLLDPLP
STTVATVVGVGQAHLVGQLCVTNPSG
NT seq
4221 nt
NT seq
+upstream
nt +downstream
nt
atggcgagcccgccgctgcacgggcccccggcgccggcgggcggcgatggccccaacctc
aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag
aagcacggtcacaagcgctttttcgtgctgcgcgggcccggcgcgagcagcgacgaggcg
acagcgggcgggggtccggcgccgcagcctccgcggctcgagtactatgagagcgagaag
aagtggcggagcaaggcgggcgccccgaagcgggtcatctcgctggactgctgcctgaac
atcaacaagcgcgcggacgccaagcacaagtacctgatcgccctctacaccaaggacgag
tacttcgccgtggcagccgagaacgagcaggagcaggagggctggtaccgcgcgctcacc
gacctggtcagtgagggccgcgcgggtgccggcgactcggcccccaccgcgatccacgcc
gggtcctgcagcgcctccttgcccggcaccctgggcggctctgccggctccgatgacagc
tacgggctggtggcgcccgccacggccgcctaccgcgaggtgtggcaggtgaacctgaag
cccaagggcctgggccagagcaagaacctgacaggcgtgtaccgcctgtgcctgtctgcg
cgcaccatcggcttcgtgaagctgaactgcgagcagccgtcggtgacgctgcagctcatg
aacatccgccgctgcggccactccgacagctttttctttatcgaggtgggtcgctcggct
gtcaccggccccggagaactgtggatgcaggctgacgactcagtggtggcccagaacatc
catgagaccatcctggaggccatgaaggcgctcaaggagctcttcgagttccggccgcgc
agcaagagccagtcgtctggctcctctgccactcaccccatcagcgtccccggcgcgcgc
cgccaccaccacctggttaacctgcctcccagccagacgggcctggtgcgccgcacgcgc
accgacagcctggctgccaccccgccggccaccaagtgcaactcatgccgggtgcgcacg
gccagcgagggcgacggcggcgcggcggccgggaccggggcggcgggcggcaggccggtg
tcggtggccgggagccccttgagcccggggccggtgcgtacacctctgagccgctcacac
accctgagcgccggctgcggcaaccgcgcgagcaaggtgacgctggcgccggcagggggc
gccctgcaacacagccgctccatgtccatgcccgtggcgcactcgcccccagcagctacc
agcccaggcagcctgtcgtccagcagcgggcatggctcaggctcctacccgctgcctccg
ggcccgcacccgcacctgcagcatcccctgcaccaccacgcgggccagcgtccctccagt
ggcagcgcttcagcctctggctcccccagcgatcccggcttcatgtccctggatgagtac
ggctccagccctggggacgtgagagccttctgcagccacaggagcaacacgcctgagtcc
atcgccgagacaccgcctgccaaagatgggagtgggagcgagctatacgggtacatgacc
atggacaggcccctgagccactgtggccgcccctaccgtcgagtctcaggggatggagcc
caggacttggacagagggttgaggaagaggacttactccctgaccacacctgcccggcag
cgggcggtgccccagccctcctctgcgtccctggatgaatacaccctgatgcgggccacc
ttctctggcagctctggccgcctctgcccatcctgccccacgtcttctcccagagtggcc
tatcacccttatcctgaggactatggtgacattgagattgggtcccataggagctccagc
agcaacctgggcacggatgatggttacatgcccatgacccctggagcggccctcatgggt
ggtggcagtggcagctgcaagagtgacgactacatgcccatgagccccaccagcgtgtct
gccccgaagcagatcgtgcacccacgggttgctgctgcagctctgccccccaccggcccc
gcagcgctggcacccaccaatgtggccggcagggcctttccggtgaacagggccagctac
aaggctagctccccggcggaaagctctcctgaggacagtggctacatgcgcatgtggtgt
ggcaccaagctgcctacggagagcactgacagcaagcagcttcccaacggggactacctc
aacatgtcccccagcgacgcgggcaccgcgggaaccccacccgacttcttcaccgcagcc
ttgcagggcgctggagagatgctcaggagcgtccctggctactgctacagctccttaccc
cgctcctacaaggctccctacacctgcaatggggacaacgaccagtatgtgctcatgagc
tcccccgtggggcgcatcctggaagaggagaggctggagcctcaggccagcgtggggacc
acgcacccggccagcagcgtggtggctggggtcggtgggggcagccacgctcagcctcct
cactccgtagtgccttctgcagggaggcagagtggcagtggcagtggcagtggccgcccc
gagggcttcctgagccagcgctgccgggcagtgagacccacgcgcctgtccctggagggg
ctccagaccctgcccagcatgcacgagtgccccctaccgcccgagcccaagagcccgggc
gagtacatcaacattgactttggcgaggctggagcgcgcttgtcgcccccggcccctccg
atgatgctggcttcggcggcctcgtcctcctcgctgctgtctgccagcagcccggcctcg
tccctgggctctggcaccccgggcacgagcagtgacagccggcagcgctccccgctctct
gactacatgaacctggacttcaattcccccaagtcacccaaggcagatacccagagcggg
gaccccgtgggctccttggatggcctcctatcccctgaggcctcctccgggtacccgccg
ctgcccccgcgccctgccgccccctcctctagttcgcagctgcagccacctccgccaccc
cctccaggggagctgtaccgcctgcctcctgcacccacatcccagggccccagtgctgcc
tcctcttcgtcctcggagactggggacaatggtgactacaccgagatggcctttggcgtg
gctgccaccccgccacaacccatcgtggccccccccaagccagatggtgcccgcgtgacc
agccccacgtccggcatgaagaggctgagtctcatggatcacgtgtctggggtcgaggcc
ttcctgcaggctggccagcccccagacccccaccggggggccaaggtcatccgtgcagac
ccacaggggggccgccgccgccacagctctgagaccttctcctccaccaccactgtgact
cccgtgtcgccgtcctttgctcacaacccgaagcgccacaactcggcctccgtggaaaat
gtctctctcaggaaaagcagcgaagggagtggcagcggcgtccttggtgggggtgacgag
ccccctgcgtcccctcggcagccgcagccaccactcccccagcaggcgcggccatggaca
ccaagtcagcctgggggcctggttggctgccccgggggcagcggctctcccatgcgcagg
gagacctcagctggcttccagaatggtctcaactacattgccatcgatgtaagggatgag
ccggggctattgccgtctccacagcagcacccacacctgcatccgcatccgcagccaggc
gacaagagtgcctggggccggacccgtagcctcgggggtctcatcagcactgtgggggct
ggcagcaccggtggggtgtgtggagggccaggccctggagcgctgccctccaacacctat
gccagcattgacttcttgtcccatcacctgaaggaggccaccattgtgaaagacatccat
gatctatccaggagagcccccttctcctcctgtgcggaggaggcctcctggccagcagca
gccccctccacccatagtgcctcctgctctgaaagcctgctgctgctggaccccctgcct
tccaccacagtggccactgtagtcggagtagggcaggcccatttggttgggcagctctgt
gttaccaacccatcaggctga
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