KEGG   Maylandia zebra (zebra mbuna): 101473405
Entry
101473405         CDS       T02814                                 
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
  KO
K01116  phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
Organism
mze  Maylandia zebra (zebra mbuna)
Pathway
mze00562  Inositol phosphate metabolism
mze01100  Metabolic pathways
mze04012  ErbB signaling pathway
mze04020  Calcium signaling pathway
mze04070  Phosphatidylinositol signaling system
mze04370  VEGF signaling pathway
Module
mze_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mze00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    101473405
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    101473405
   04370 VEGF signaling pathway
    101473405
   04020 Calcium signaling pathway
    101473405
   04070 Phosphatidylinositol signaling system
    101473405
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mze04131]
    101473405
Enzymes [BR:mze01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     101473405
Membrane trafficking [BR:mze04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    101473405
 Endocytosis
  Macropinocytosis
   Phospholipase C
    101473405
SSDB
Motif
Pfam: PI-PLC-X SH2 PI-PLC-Y EF-hand_PLCG2 C2 PH SH3_1 EF-hand_PLCG1 SH3_9 PH_12 SH2_1 SH3_2 EF-hand_6 EF-hand_9 GDPD EF-hand_7 Csm1
Other DBs
NCBI-GeneID: 101473405
NCBI-ProteinID: XP_004572376
UniProt: A0A3P9CMA2
LinkDB
Position
LG17:complement(10632175..10676190)
AA seq 1312 aa
MCAARFSGCLNGCAEEAPSSVAGAAGSVMVSRMLDWSEAGARILHSLEMGTVMTIFYQKK
SQRPERRTFQIRQDTRQIVWSRNPDKIEGEIDIREIRELRLGKGSRDFERYPEEARKLDS
THCFIVLYGLEFRLRTLSVAAFSEEEVNMWITGLNWLMMDTQRAPAPQQIDRWLRKQFEV
MDRSHEGSITVKDVKALLPQVNYRVPNMRFLKDKLQEVEARSDLSYPNFAQLYRTLMFDA
QRSIIEQLELSFPLRNVDRPELCQISLYDFQKFLQMDQKESWASDLGRVREFLMGYMRGA
PQPEPMLQLDEFLTFLYSKENSVCDPRLSPVVPDDMKRPLSQYWISSSHNTYLTGDQFSS
ESSLEAYARCLRMGCRCIELDCWDGPDDLPIIYHGHTLTSKIKFLDVLHTIKEHAFVISE
YPVILSIEDHCSVVQQRNMATHFKKVFGDLLLTKPVDNNAEELPSPYQLRRKILIKHKKL
VEGTLYEEVTSASYSENDISNSLKNGILYLEDPIDHTWTPHYFVLTSNKIYYSEETSHYQ
TADEEEDDEGKEECNNNEQHCAERWFHGKLGGGRDGRQVAEKLLQEYCEGGAKDGTFLVR
ESETFVGDYTLSFWRSGRVQHCRIHSRQESGSTRFYLTDNLVFDSLYRLICHYRDTPLRC
NEFEMRLGNPVPQPNAHESREWYHSNLSRVQAEHMLMRVPRDGAFLVRKRSEHNSYAISF
RAEGKIKHCRIQQEGRLFMLGSSAEFESLVDLVSYYEKHPLYRKMRLRYPINEDTLDRMG
TTELDYGALYEVRTPHFYVEANKMPTARCTVKALYDYRAQREDELCFPKQALILNVDKQE
GGWWRGDYGGKKQLWFPANYVEEVPSSPTREMDEASTENSPLGTFLKGFIDVPTCHLVVH
KDGKNSRAFVFTIHSQHLSSHPVQTLDVAADSLEDLTGWVSKIREAAQNADARMQEEKQM
ERRKKIAVELSDLVVYCRPVPFNEDKIGTERACYRDMSSFPETKAEKFATRGRGKRFLQY
NRRQLSRIYPRGQRLDSSNYDPLPMWLCGSQLVALNFQTPDKPMQLNQALFMLGGGSGYV
PQPDIMRDDMFDPFDKDTLHVEPITIQLQVLGARHLPKNGRSIVCPFVELEICGADYDSY
KCKTDVVADNGLNPVWVQKQFVFDIHNPTFAFLRFTVYEEDMFSDPNFLAQATYPVRLLK
TGYRSVPLKNSYSEELELASLLVHIEIVNAKEEDDENLYTSIQRLRDRTCELSNQVSLLE
RSGSADLSYQQSLEELRAAQDQLSELVEARNRRLMEKKRREKLRQQVIAKRS
NT seq 3939 nt   +upstreamnt  +downstreamnt
atgtgtgcagccagattcagtggctgcctcaatggctgtgctgaggaggcccccagtagt
gttgcaggggctgctggttcagtcatggtctccaggatgctggactggtctgaggcaggt
gcccgcatcctccacagcctggaaatgggcacagtgatgaccatcttctatcagaaaaag
tctcagcgccctgagaggagaacgttccagataaggcaggacacgaggcagatagtgtgg
agcagaaacccagacaaaatagaaggagagatcgacatacgggagatccgggagctgcgg
ttggggaagggctcccgtgattttgagcgctaccctgaggaggctcgtaagctggactcc
acccactgctttatagtgctgtacggcctggagtttcgcctccggaccctcagtgtagct
gccttcagtgaagaggaagtcaacatgtggatcactggactcaactggctaatgatggac
acgcagagggcaccggcaccacaacagattgacaggtggctgaggaaacagtttgaagtc
atggacaggagccacgagggcagcattacagtaaaggatgtgaaagctctgctgcctcag
gtcaactatcgagtgcccaacatgcgctttctcaaagacaagctacaggaggtggaggcc
aggagcgacctgtcataccccaactttgcacagctctacagaacactgatgtttgatgca
cagaggagtattattgagcagctggagctctccttccctctgcgaaatgttgacagacca
gagctatgtcaaatctccctctatgactttcaaaagtttttacagatggaccagaaggag
tcctgggcgtcagatcttggtcgtgtcagggagtttcttatgggctacatgaggggggca
ccacagcctgagccgatgctacaactggatgagttcctgaccttcctgtactctaaagag
aattctgtgtgtgaccctcgtctttcacccgtagttcctgatgacatgaaaaggccattg
tctcagtactggatctcatcttcgcacaacacgtacctgacaggtgaccagttttccagt
gaatcatctctagaagcctacgctcgctgtctgaggatgggctgccgctgcattgaactg
gactgctgggatggacctgatgacctgccaatcatctaccacggccacacattaacttcc
aagatcaaattcctggatgtgctgcataccatcaaagaacatgcctttgttatatctgag
tatcctgtgatcttatccatcgaggaccactgcagtgtggtccagcagaggaacatggcc
acgcacttcaagaaagttttcggagatctgctgctcaccaaaccggttgacaataacgca
gaggagcttccttcgccctaccagctccgcaggaagatcctcatcaaacacaagaagctg
gttgaaggaaccctgtatgaagaggtgacgtcagccagctactctgaaaacgacatcagt
aactccctaaagaacggcatcctttacctcgaagaccccattgaccatacatggacgcca
cattattttgtcttgaccagtaataagatttactactctgaggagacgtctcattatcag
acagctgatgaagaggaggatgatgaaggaaaggaggagtgcaacaacaatgagcagcac
tgtgcagagcgctggtttcatgggaagctgggtggaggacgcgatggccgacaggtggct
gagaaactcctgcaggagtactgcgagggcggggccaaagacggcaccttcctggtccgg
gagagtgagacatttgttggagactacaccctctccttctggcgctctggtcgggtccag
cactgcaggatacattcacgtcaagagtctggctccacccgcttctacctgactgataac
ctggtgtttgacagcctctaccggctcatctgccactatagagacacgccgctccgctgc
aacgagtttgagatgaggctgggaaaccctgtacctcagccgaatgcacacgaaagccga
gagtggtaccactccaacctgtcccgtgttcaggctgaacacatgctgatgcgtgtgccc
agagacggagctttcctggttcgaaaacgcagtgaacacaactcctacgccatctccttc
agggcagagggtaagatcaaacactgccgtatccagcaagaaggccgtctcttcatgttg
ggtagctcggcagagtttgagagtctggtggatctggtgagctactatgagaaacatcct
ctgtatcgtaaaatgaggctccgctaccccatcaatgaagacactctggaccggatgggc
accacggagcttgactatggagcgctgtatgaagttcgcactcctcatttctatgtggag
gctaataagatgcccacagcacggtgtacggtcaaagctctgtatgactatcgagctcag
agagaagacgagctatgtttccccaaacaagcgctcatcctgaatgtggataagcaggag
ggcggctggtggagaggtgactatggaggaaagaagcagctgtggttccctgcaaactat
gtagaggaggtccctagttcccccactagagagatggatgaagcatccacagagaacagt
cctctgggaactttcctcaaaggcttcatagatgtaccaacctgccacctggtggtgcat
aaagacggaaagaattcccgggcctttgtgttcactatccactcccaacacctctcttct
catccggtccagactctggacgtagcagctgacagtctggaagatctcaccggctgggtc
agcaagatcagagaggctgcacagaatgctgatgcacgaatgcaggaggagaaacagatg
gagaggaggaagaagattgcagtggagctgtctgacctcgtggtctactgcagaccagtg
cccttcaatgaggacaagattgggacggagcgagcatgttaccgggatatgtcctccttc
ccggagacaaaggcagaaaagtttgcgacccgtggccgagggaaacgctttctgcagtac
aaccgtcgtcagctttccaggatttatcccagaggacagaggctggactcctccaactat
gaccctctacctatgtggctctgcggctcacagctggttgcactcaatttccagacccca
gataaacccatgcagctgaaccaagctttgttcatgcttggaggtgggagtggctatgtt
ccccagcctgacatcatgagggatgacatgtttgaccctttcgacaaggacacattgcac
gtggagccaatcaccatccaattacaggtgctgggagctcgccatctgcctaagaatggt
cggagcattgtctgtccttttgtagagttggaaatctgtggagccgactatgacagctac
aagtgcaagacagatgttgtagctgataatggtctgaatcctgtgtgggtgcagaagcag
tttgtgtttgatatccacaaccctaccttcgcctttctgcgcttcactgtctacgaggag
gacatgttcagcgatcccaacttcctggcacaggcaacctacccagtccgtctgctcaaa
acaggctacaggagtgtacctctaaagaacagctacagtgaggagctcgagctagcgtcc
cttctggttcacatagaaatcgtcaatgctaaggaggaagacgatgagaacttgtacaca
tccatccagcggttgcgagatcgaacctgcgagctgtccaaccaggtttctctcctggag
aggtcaggctccgcagacctgagctatcagcaaagtctggaggagctccgagccgctcag
gaccagctgagtgagctggtggaggctcgcaaccgcaggctgatggagaagaagagaagg
gagaagctgagacaacaggtgatagcaaagcgcagctaa

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