Maylandia zebra (zebra mbuna): 101474045
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Entry
101474045 CDS
T02814
Name
(RefSeq) tyrosine-protein kinase JAK2
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
mze
Maylandia zebra (zebra mbuna)
Pathway
mze04217
Necroptosis
Brite
KEGG Orthology (KO) [BR:
mze00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
101474045
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mze01001
]
101474045
Enzymes [BR:
mze01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101474045
Protein kinases [BR:
mze01001
]
Non-receptor tyrosine kinases
JAK family [OT]
101474045
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
FERM_C_FAK1
Kinase-like
ABC1
LRR_RI_capping
Motif
Other DBs
NCBI-GeneID:
101474045
NCBI-ProteinID:
XP_004562090
UniProt:
A0A3P9CMB0
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Position
LG15:29348443..29367403
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AA seq
1113 aa
AA seq
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MDLSEEESTPLVIRDRGGSQRSSSSTVPNLQVNFFPVKKEATTLQITSGQISAENVCIQA
GKKCGILPVYLSLFGLASEDLSFWYPPSHMFDTDENLKVHFRVRYFFGNWFGQEPRSSYR
YSLTRDRISPVLDYSVIDYLFAQLRNDFIESKAGIAPPLTLQEECLGLAVLDLWRMAKER
NQSVRELCKTVSYKSCLPMSHRHDIQKRNRLDRYRIRNTLKRFLKKLGNCSVDECSLKLK
YLIELSGIEPSVGTETFQVNHSSSHPKSDFSLVRVTGETGIQTAGSINNSQVLSRVEWQT
FCDFQEIIDISIQRVCHEQVPQDSRMVTITRKDDSCLEVKFQSLKEALSFVSLVDGYFRL
TTDSSHFFCQDIAPPSILEGIKNHCHGPITSEFAVNKLKKSGYKGGTFLLRQSPKNYDNF
FLTVCVQTPLGLDYKDCLINKNEHYSLFGVQKSFSSLRELTSHYQHNKLLLAEVPVKLTC
CCPPRPKELTNLIIIRNCSSVEAPGSPTTERNKFSHIQFHMIKYEDLSCDESLGQGSFTR
IFKGKKIDIHDGEKRVTEVLLKELDATHKNCWESFFEAASLMSQIAHRHLLLVYGVSVHG
AKNIMVQEYVKYGALDLYLKRGRSVSVSWKLDVAKQLASALNFLEEKNIVHGNICAKNLL
LAREGDPSQGSSPFIKLSDPGISMAMVGKDVILDRIPWVAPEVLGAPEKLTLECDKWSFG
ATVWEIFNNGNSLLRGWNLDQKKQFYESFQQLPPSQWTELADLISQCMDYQADFRPSCRS
IIRQLNSLITSDYVILHATEPVTQSPVCRSYSHPQHDQTLFEERYLRYISPLGKGNFGSV
ELCRYDPLGDNTGELVAVKKLQSNKQSNLEDFQKEVNTLHVLHCDYIVKYKGVCYSMGRL
SMSLVMEYLPYGSLIGYLEKNKHNINTRRMLLFASQICKGMEYLQSLRYVHRDLAARNIL
VASETLVKIADFGLTKVIPHNKDYYRVTQPGESPIFWYAPESITESRFSQKSDVWSFGVV
LHEIFSYCDISFNPKRLYMQEIGHNVLGTSISVHLANLLKGNWRLPPPLNCPPKVYLMMR
QCWAHDFDERPFFSNLGNEIETMIQDERENSKG
NT seq
3342 nt
NT seq
+upstream
nt +downstream
nt
atggatctcagcgaggaagagtcaactcctctggtgatcagagaccgcggaggcagccag
aggtccagttcaagcactgttcctaatttacaagtcaacttcttccctgtcaaaaaggaa
gcaacaacattacagatcacatctggacaaatatctgctgaaaatgtctgcatccaagca
gggaagaaatgtggaatcttgccggtatacctaagtctatttggtttggcatctgaagac
ctctcattttggtatcctccttctcacatgtttgacactgatgaaaacttaaaagtccat
ttcagagtcaggtacttctttggaaattggtttgggcaagaaccaagatcttcataccgc
tacagtttgactagagacagaatcagtccagtactcgactacagtgtcattgactatctt
tttgcccagcttcgaaatgacttcattgaaagtaaggcaggcatagccccaccattgact
cttcaggaggaatgccttggccttgcagtgctcgacttgtggagaatggccaaggagcgc
aaccagagtgttagagagctctgcaagactgtcagctacaaatcctgccttcccatgtca
catcgccatgacatccagaaacgaaaccggctggaccgctaccgaattagaaataccctc
aagcgtttcttaaagaagcttggcaactgctccgtagatgagtgcagcctgaaactcaag
tacctgattgagctgtctggcattgagccttctgttggaacggaaaccttccaagtgaat
cattcttcctcccatccaaagtcagacttctctcttgtgcgggtcacaggggaaacagga
atccaaaccgctggaagtatcaataacagccaggttttgtcaagagttgagtggcagacc
ttctgtgattttcaagaaatcattgacatcagtatacagcgggtatgccatgagcaggtt
ccccaagacagcaggatggtgactataacacgaaaggatgacagctgcttggaagtcaag
ttccagagtctcaaagaggcactttcgtttgtgtcacttgttgatggttacttcagactg
accacggactcaagccacttcttctgccaagacattgctccgccaagtattctagaggga
atcaaaaaccattgtcatggcccaataacatcagagtttgcagtcaacaaattgaaaaag
tcaggatacaaaggtggtaccttccttctgcggcagagtccgaagaactatgacaacttt
ttcctcactgtttgtgttcagactccacttggacttgattataaagactgtctcattaat
aaaaatgagcactacagcctctttggtgtccagaaatcattttccagcttgagagagctt
accagccactatcaacacaataagctcctgctggctgaagtacctgtcaagttaacctgc
tgctgtccaccccgacccaaagagctcacaaatttgatcatcatacgcaactgcagctct
gtagaagctccaggctctccaacaaccgaaaggaacaaattcagtcacatccagtttcat
atgatcaaatatgaggacctgagctgtgacgaaagcctcggtcagggctctttcactcga
atctttaaaggcaaaaaaatcgacattcatgacggggagaaacgtgtgaccgaagttctg
ctgaaagagctcgatgcgactcacaagaactgctgggagtcattctttgaagctgccagc
ctgatgagtcagattgcacacagacacctgctccttgtatacggtgttagtgttcacgga
gcaaagaacatcatggtgcaggagtatgtcaagtacggggcccttgacctttacttgaaa
agggggagatctgtatcagtgagctggaaacttgacgtagccaaacagctcgcatcagcc
ctcaacttcctggaagagaagaacattgttcatggaaatatctgtgccaaaaatctgctg
ctggccagagaaggtgacccctctcaggggagctctcctttcattaagctgagtgatccg
ggcatcagtatggccatggtgggcaaagatgtcattctggacaggatcccctgggtggcc
cccgaggtgttgggcgctccagaaaaactgaccctcgagtgtgataaatggagctttggc
gccacagtgtgggaaatctttaacaatggaaactccctgctacgaggctggaacctagat
cagaagaagcagttttatgagagtttccagcagctgcctccctctcagtggacagagcta
gcagatctgatcagtcagtgtatggactaccaggcagacttcagaccttcatgtcgcagt
attatccgtcaactcaacagtctcatcacttcagactatgtgatacttcatgctaccgaa
cctgtcacacagagccccgtgtgcagatcttacagccaccctcagcacgaccagacattg
tttgaggagagatacttgcgctacatctcccctctgggaaaagggaactttggcagcgtg
gagctttgccgttatgacccgctgggtgataacactggtgagctggtggctgtgaagaag
ctgcagtccaacaagcagtcaaacctggaggacttccaaaaggaggtcaacaccctccac
gtcttacactgcgactacatcgtcaaatacaagggagtctgctacagcatgggtcgcctc
agcatgagtctagtgatggagtacctgccctatggcagccttattggctacttagagaag
aacaaacacaacatcaacaccaggcggatgttactatttgcttctcaaatttgtaagggg
atggagtacctgcagagcctgcgttatgtgcaccgagaccttgcagcccgaaatatcctt
gtagccagtgagacgctggtaaaaatcgctgattttgggctgaccaaggtcattccacat
aataaggactactaccgtgtcacccaaccaggagagagccccatcttctggtatgcccca
gagtccatcactgagtccagattctcccaaaaatcagatgtctggagtttcggggttgtt
cttcatgaaatcttctcttactgtgatataagtttcaatccaaaaagactttatatgcag
gagattgggcacaacgtgctgggtacatccatttcagtgcatctggcaaatctactgaag
ggtaactggaggttaccaccacctttaaactgcccgcccaaggtgtaccttatgatgagg
cagtgctgggcacatgactttgatgagcgtccatttttctccaaccttggaaacgaaatt
gaaactatgatccaggatgaaagagagaactctaaaggctga
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