Maylandia zebra (zebra mbuna): 101482216
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Entry
101482216 CDS
T02814
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
mze
Maylandia zebra (zebra mbuna)
Pathway
mze04120
Ubiquitin mediated proteolysis
mze04144
Endocytosis
mze04330
Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:
mze00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
101482216
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
101482216
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101482216
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mze04131
]
101482216
04121 Ubiquitin system [BR:
mze04121
]
101482216
Enzymes [BR:
mze01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
101482216
Membrane trafficking [BR:
mze04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
101482216
Ubiquitin system [BR:
mze04121
]
Ubiquitin ligases (E3)
HECT type E3
101482216
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
101482216
NCBI-ProteinID:
XP_004547686
UniProt:
A0A3P9B973
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Position
LG5:30223430..30236778
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AA seq
864 aa
AA seq
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MKAQLQVTVLSAKLKENKKTWFGPSPYVEIAVDGQSKRTEKCNNTHSPKWKQALTVIVTP
FSKLIFRVWSHQTLKSDILLGLATLEISKTLKANDMKLCEVVQTLQLCSDRDPQDLVGDL
SVCLDGMQVDPETFGLAEREQAALPNGNTRQNGDTGDRSSGGSSPSSDLDEWVIVPNVHA
VNGTSSPSRSPGGSTASLPSGPTQPPPPMRQKPAASPSSSSSSSPSELSEGPASDGSSQA
SASGCSDQQNESNARAATSSSSQTASVPKQGASASATIPRVAPINNGPLPPGWEQRVDQN
GRVYYVDHIEKRTTWDRPEPLPSGWERRVDPMGRVYYVDHITRTTTWQRPTQESVRNYEE
WQHQRSQLQGAMQQFNQRFIYGLQDQFAATASKEFDPLGPLPHGWEKRTDTNGRVYFVHH
PTRRTQWEDPRTQGLLNDKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSSLENG
PQITYVRDFKAKVQYFRFWCQQLSMPQHIKITVSRKTLFEDSFQQIMSFHPQDLRRRLWI
IFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFK
FIGRFIAMALFHGKFIDTGFSLPFYKRILNKPLGLKDLESIDPEFYNSLIWIKDNNIEEC
GLEMFFSVDKEILGEVTTHELKPDGGNILVTEENKEEYIRLVAEWRLSRGVEEQTQAFFE
GFNEVLPQQYLQYFDARELEVMLCGMQEIDLVDWQRNAIYRHYARTSKQIMWFWQFVKEM
DNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPP
YKSYEQLKEKLMFAIEETEGFGQE
NT seq
2595 nt
NT seq
+upstream
nt +downstream
nt
atgaaggcccagttgcaagttactgtgctttcagctaagctgaaggaaaacaaaaagacc
tggtttggtccaagtccatatgttgaaatagcagtggatggccagtcaaagaggactgag
aaatgcaacaacacacacagccctaaatggaagcaggctctcacagtaattgtgacgccg
ttcagcaaactgatatttcgtgtttggagccatcagacactcaagtcagacattctattg
ggtctagctacattggaaatcagcaagacccttaaggccaatgacatgaaattatgtgag
gtcgtgcagacactgcagctgtgctctgacagagacccccaggatcttgtaggtgacttg
tcagtctgtctggatggcatgcaggtagacccagaaacctttggcttggcagagagagaa
caagctgctcttccaaatggaaatacgcggcaaaatggagatactggtgacaggtcaagc
ggaggctcatcaccttcaagtgacttggatgaatgggtcattgtaccaaatgtgcatgct
gtcaatggtacaagttctccctcacggtctccagggggctccactgcatcacttccttct
ggacctactcaaccgccccctcctatgcgacagaaaccagcagcttcaccatcctcttct
agcagttcttctcctagtgaactcagcgaaggcccagcttccgatggttcctctcaggca
tcagctagtgggtgttcagatcagcagaatgaatcaaatgcaagggcggcaacatcaagt
tcctcacagacagcaagtgttcctaaacaaggggccagtgcctcagcaacaattcccagg
gtggctcccataaacaatggtcccttgcccccagggtgggagcaaagagttgaccagaat
ggacgggtatactatgtggatcacattgagaaaagaacaacctgggataggcctgagcct
ttgccttcaggatgggagcgcagagtggatccaatgggtagagtttattatgttgaccac
ataacccgaactactacatggcaaagacccacacaggagtcagtgcgtaactacgaggaa
tggcagcaccagcgtagccagcttcagggagccatgcagcaatttaaccagagattcata
tatgggctgcaagaccagtttgcagccacagccagtaaagagtttgacccactaggacct
ctgcctcacggatgggaaaagagaactgacaccaatggtagagtgtattttgtccatcac
ccaactcgcaggacacagtgggaagacccaaggacccaagggctgctgaatgacaagcct
ctgcctgagggttgggagatgaggttcactgtggatggtattccctactttgtagatcac
aataggcgaacaacaacctacattgaccctcgcacagggaaatcctcacttgagaatggg
ccacagataacttatgtcagggacttcaaagccaaagtgcaatacttcagattctggtgt
cagcaactgtcgatgcctcagcacattaaaattacagtttcacgcaaaactttgtttgag
gattcatttcaacagatcatgagtttccacccacaagatcttaggcgtagactttggata
attttccctggtgaggaaggcttggactatggaggtgtggccagggaatggttcttcttg
ctgtctcatgaggtgctgaatccaatgtactgtttgtttgagtatgctggcaaggacaac
tactgtcttcagatcaaccctgcctcttacatcaacccggatcaccttaagtacttcaag
ttcattgggcgatttattgccatggccttgttccatggcaaatttatcgacacaggtttc
tcgctgcccttttacaaacgtattctgaacaaacctctgggtctgaaagacctggagtcc
atagatccagaattctataattcactcatctggatcaaggacaataatatagaggagtgc
ggtctggaaatgttcttctccgttgacaaggagatacttggggaggtcaccacacatgag
cttaaaccagatggagggaacattctagtaactgaagaaaataaagaggaatacatcagg
ttagtggcagagtggaggctatccagaggtgtggaggagcagacacaggctttctttgag
ggcttcaatgaagttcttccacagcaataccttcagtactttgatgctagagaattagag
gtgatgctgtgcggtatgcaggagatagacttggtggactggcagagaaacgcaatctat
agacattatgcccgaactagcaagcagataatgtggttctggcagtttgtgaaggagatg
gacaacgaaaaaaggatgagacttctgcagtttgtcacaggaacctgtcgtcttcccgtg
ggcggcttcgctgatctaatgggaagcaatggtccacagaagttttgcattgagaaagtt
ggaaaagaaaactggcttccacgaagccacacatgctttaatcgtctggacctccctcct
tataagagctacgaacagctgaaggagaaactcatgtttgccatagaggaaacagaagga
ttcgggcaggagtaa
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