Maylandia zebra (zebra mbuna): 101485719
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Entry
101485719 CDS
T02814
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
mze
Maylandia zebra (zebra mbuna)
Pathway
mze00140
Steroid hormone biosynthesis
mze01100
Metabolic pathways
Module
mze_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
mze_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
mze_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
mze00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
101485719
Enzymes [BR:
mze01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
101485719
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
101485719
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_4
Polysacc_synt_2
NAD_binding_10
NmrA
KR
adh_short
Motif
Other DBs
NCBI-GeneID:
101485719
NCBI-ProteinID:
XP_004573053
UniProt:
A0A3P9CUV2
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Position
LG16:4533712..4537613
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AA seq
374 aa
AA seq
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MSLRGDVCVVTGACGFLGKRLVRLLLEEEKMAEIRLLDKQMQLQYLQSLEDCKGETKLRA
FEGDMRDGDFLIKCCRGASIVFHIASIIDIKDSVEYSEIFGVNVKGTQLLLEACIRENVP
SFIYTSTIEVMGPNSKGEPIINGSEDTVYDISLGINYSKTKSEAEEKTLKANGEVLQNGG
QLATCALRPAYIYGEGCRFLLGHMVDGIKNRNVLLRMSLPEALVKPVYVGNVATAHLQAS
RSLKDPQKRNAVGGKFYFVSDDTPPVSYSDFNHAVMSPLGFSIQEKPMLPLTLFYLLTFL
METVAWILRPFIRIVPPLNRQLLIMLNTPFSFSYEKAKRDLGYVPKYSWEEARKRTTEWL
ASQLPAERERILSK
NT seq
1125 nt
NT seq
+upstream
nt +downstream
nt
atgtctctgcgaggtgatgtgtgcgtggtgacgggggcctgtggattcttgggaaagagg
ctggtgaggctgctgctggaagaagagaaaatggctgagattcgacttctggacaaacag
atgcagctgcagtatttgcagagtttggaggactgcaaaggtgagacaaagctgcgagct
ttcgaaggggacatgagggacggtgatttcctgatcaaatgctgccgtggggcatcgatc
gttttccacatcgcatccatcattgacatcaaagactcagtggagtacagtgagattttc
ggagtgaatgtcaaaggaacccagctgcttttggaggcatgtattcgggagaacgtgccg
tccttcatatacaccagcaccattgaagtgatggggccaaactccaagggagaacccata
atcaatggcagtgaggacaccgtctatgacatcagtttgggcatcaactacagcaagacc
aagagtgaggctgaggagaaaaccctgaaggccaacggtgaggtgctccagaacggaggc
cagctagccacctgtgcactcagacctgcgtatatctatggagagggctgccgcttcctc
ctaggccacatggtcgatgggataaaaaaccgaaatgttctgcttcgtatgtcgctcccc
gaggcccttgtgaagcctgtctatgtgggcaacgtggccaccgctcatctccaagcatcc
cgcagcctcaaagatccgcagaaaagaaatgctgttggagggaagttttacttcgtttct
gatgacacaccacctgtgagttattcagacttcaaccacgccgtgatgtctcctctgggt
tttagtattcaagagaaacccatgttgccactcaccctcttctacttactaactttcctt
atggagacagtagcctggatcctacggcctttcatacgcatcgtcccgccactgaaccgt
cagctcctcatcatgttgaacacgccattcagtttttcctatgagaaagccaagagggat
ctaggatatgtccccaaatatagctgggaggaagcacgcaaacgcaccactgaatggctc
gcctcccagttgccagcagagagagaaagaatcttgtctaaatag
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