KEGG   Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise): 112394295
Entry
112394295         CDS       T08872                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4 isoform X1
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
nasi  Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)
Pathway
nasi01522  Endocrine resistance
nasi04110  Cell cycle
nasi04115  p53 signaling pathway
nasi04151  PI3K-Akt signaling pathway
nasi04218  Cellular senescence
nasi04530  Tight junction
nasi04660  T cell receptor signaling pathway
nasi04933  AGE-RAGE signaling pathway in diabetic complications
nasi04934  Cushing syndrome
nasi05160  Hepatitis C
nasi05162  Measles
nasi05163  Human cytomegalovirus infection
nasi05164  Influenza A
nasi05165  Human papillomavirus infection
nasi05166  Human T-cell leukemia virus 1 infection
nasi05167  Kaposi sarcoma-associated herpesvirus infection
nasi05169  Epstein-Barr virus infection
nasi05200  Pathways in cancer
nasi05203  Viral carcinogenesis
nasi05212  Pancreatic cancer
nasi05214  Glioma
nasi05218  Melanoma
nasi05219  Bladder cancer
nasi05220  Chronic myeloid leukemia
nasi05222  Small cell lung cancer
nasi05223  Non-small cell lung cancer
nasi05224  Breast cancer
nasi05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:nasi00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    112394295 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    112394295 (CDK4)
   04115 p53 signaling pathway
    112394295 (CDK4)
   04218 Cellular senescence
    112394295 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    112394295 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    112394295 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112394295 (CDK4)
   05203 Viral carcinogenesis
    112394295 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    112394295 (CDK4)
   05225 Hepatocellular carcinoma
    112394295 (CDK4)
   05214 Glioma
    112394295 (CDK4)
   05220 Chronic myeloid leukemia
    112394295 (CDK4)
   05218 Melanoma
    112394295 (CDK4)
   05219 Bladder cancer
    112394295 (CDK4)
   05224 Breast cancer
    112394295 (CDK4)
   05222 Small cell lung cancer
    112394295 (CDK4)
   05223 Non-small cell lung cancer
    112394295 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    112394295 (CDK4)
   05160 Hepatitis C
    112394295 (CDK4)
   05164 Influenza A
    112394295 (CDK4)
   05162 Measles
    112394295 (CDK4)
   05163 Human cytomegalovirus infection
    112394295 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    112394295 (CDK4)
   05169 Epstein-Barr virus infection
    112394295 (CDK4)
   05165 Human papillomavirus infection
    112394295 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    112394295 (CDK4)
   04934 Cushing syndrome
    112394295 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    112394295 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:nasi01001]
    112394295 (CDK4)
Enzymes [BR:nasi01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     112394295 (CDK4)
Protein kinases [BR:nasi01001]
 Serine/threonine kinases: CMGC group
  CDK family
   112394295 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo Haspin_kinase ABC1 Kinase-like
Other DBs
NCBI-GeneID: 112394295
NCBI-ProteinID: XP_024592799
UniProt: A0A341AS99
LinkDB
Position
Unknown
AA seq 303 aa
MATPRYEPVAEIGIGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFSPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKAEG
NPE
NT seq 912 nt   +upstreamnt  +downstreamnt
atggctacccctcgatatgagccagtggctgagattggtattggtgcctatgggacggtg
tataaggcccgtgatccccacagtggccactttgtggccctcaagagcgtaagagtcccc
aatggaggaggtgctggagggggcctgcccatcagcacagtccgtgaggtggctttactg
cggcggctggaggcttttgagcatcccaatgttgtgcggctgatggacgtctgtgccaca
gcccgaactgaccgggagaccaaagtgaccctggtgtttgagcatgtggaccaagaccta
aggacatatctggacaaggcacccccgccaggcctgccagtggagaccatcaaggatctg
atgcgccagtttctaagaggcctagatttccttcatgccaactgcatcgttcatcgagac
ttgaagccagagaacattctggtgacaagtggtgggacagttaagctggccgactttggc
ctggccagaatctacagctaccagatggcacttacccctgtggttgttacactctggtac
cgtgctccagaagttcttttgcagtctacatatgcaacacctgtggacatgtggagtgtt
ggctgtatctttgcagagatgtttcgtcgaaagcctctcttctgtggaaactctgaagct
gaccagttaggcaaaatctttgacctgatcggactgcccccagaggatgactggccccga
gatgtgtctctaccccgaggagccttttcccccagagggccccgccccgtgcagtcggtg
gtacctgagatggaagagtctggggcacagctgctgctggagatgctgacttttaaccca
cacaagcggatctctgccttccgagccctgcagcactcctatctacataaggcagaaggt
aacccagagtga

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