KEGG Orthology (KO) [BR:nasi00001]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
112395316
00670 One carbon pool by folate
112395316
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
112395316
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
112395316
Enzymes [BR:nasi01000]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.3 dihydrofolate reductase
112395316
150 aa
MTTTSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEPPQGAHFLAKSLDXC
LKLIEQPELTNTVDMVWIVGGSSVYKEAMNKPGHLRLFVTRIMQEFESDTFFPEIDLDKY
KLIPEYPGVPSDVQEEKGIKYKFEVYEKNN