Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise): 112396733
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Entry
112396733 CDS
T08872
Symbol
IRS1
Name
(RefSeq) insulin receptor substrate 1
KO
K16172
insulin receptor substrate 1
Organism
nasi
Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)
Pathway
nasi04022
cGMP-PKG signaling pathway
nasi04068
FoxO signaling pathway
nasi04081
Hormone signaling
nasi04140
Autophagy - animal
nasi04150
mTOR signaling pathway
nasi04151
PI3K-Akt signaling pathway
nasi04152
AMPK signaling pathway
nasi04211
Longevity regulating pathway
nasi04213
Longevity regulating pathway - multiple species
nasi04722
Neurotrophin signaling pathway
nasi04910
Insulin signaling pathway
nasi04920
Adipocytokine signaling pathway
nasi04923
Regulation of lipolysis in adipocytes
nasi04930
Type II diabetes mellitus
nasi04931
Insulin resistance
nasi04932
Non-alcoholic fatty liver disease
nasi04935
Growth hormone synthesis, secretion and action
nasi04960
Aldosterone-regulated sodium reabsorption
nasi05010
Alzheimer disease
nasi05206
MicroRNAs in cancer
nasi05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
nasi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
112396733 (IRS1)
04022 cGMP-PKG signaling pathway
112396733 (IRS1)
04151 PI3K-Akt signaling pathway
112396733 (IRS1)
04152 AMPK signaling pathway
112396733 (IRS1)
04150 mTOR signaling pathway
112396733 (IRS1)
09133 Signaling molecules and interaction
04081 Hormone signaling
112396733 (IRS1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
112396733 (IRS1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
112396733 (IRS1)
04923 Regulation of lipolysis in adipocytes
112396733 (IRS1)
04920 Adipocytokine signaling pathway
112396733 (IRS1)
04935 Growth hormone synthesis, secretion and action
112396733 (IRS1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
112396733 (IRS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
112396733 (IRS1)
09149 Aging
04211 Longevity regulating pathway
112396733 (IRS1)
04213 Longevity regulating pathway - multiple species
112396733 (IRS1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
112396733 (IRS1)
09164 Neurodegenerative disease
05010 Alzheimer disease
112396733 (IRS1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
112396733 (IRS1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
112396733 (IRS1)
04932 Non-alcoholic fatty liver disease
112396733 (IRS1)
04931 Insulin resistance
112396733 (IRS1)
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Ortholog
Paralog
GFIT
Motif
Pfam:
IRS
PH
PH_11
Motif
Other DBs
NCBI-GeneID:
112396733
NCBI-ProteinID:
XP_024596323
UniProt:
A0A341B0M9
LinkDB
All DBs
Position
Unknown
AA seq
1248 aa
AA seq
DB search
MASPPETDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP
KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH
HDGAAAPGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLI
GIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV
DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLT
RRSRTESITATSPASLVGGKQGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHR
GSSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP
SDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGASTLTAPN
GHYILPRSGNGPRYIPAAGLGTSPALTGDEAASAADLDNRFRKRTHSAGTSPTISHQKTP
SQSSVASIEEYTEMMPAYPPGGGSGGRVPSYRHSAFVPTHSYPEEGLEMHPLERRVGHHR
PDTSNLHTDDGYMPMSPGVAPVPGSRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPN
GYMMMSPSGSCSPDIGGGPSSGGSSGAAPSGSSYGKLWTNGVGGHHSHALPHPKLPVESS
SGKLLSCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGELE
EGARHQHHRLSSSSGRLLYAAAAEDSSSSTSSDSLGGGYCAARPEPGLPHLHHQVLQPHL
PRKVDTAAQTNSRLARPTRLSLGDPKASTLPRAREQPQPQPQPPPPLLPPPEPKSPGEYV
NIEFGSDQPGYLSGPGASHSSPSVRCPSQLQPAPREEETGAEEYMNMDLGPGRRAAWRES
PGVQPGSMGPAPPGAASVCRPTRAVPSSRGDYMTMQMGCPRQSYVDTSPVAPISYADMRT
GSGSGLVEEASLPGAAAATPSSSSKASASPAAPQGAEELAARSSLLGGPQGPGGSSAFTR
VNLSPNRNQSAKVIRADPQGCRRRHSSETFSSTPSATRAGNTVPFGGGAAAGGGGGGSSS
TEDVKRHSSASFENVWLRPGELGGAPKELAQVCGATGGLENGLNYIDLDLVKDFNQSPQE
RPAPPQPSPPPPPHQPLGRSEGGSTSRSSEDLSAYASISFQKPPEDLQ
NT seq
3747 nt
NT seq
+upstream
nt +downstream
nt
atggcgagccctcccgagaccgacggcttctccgacgtgcgcaaggtgggctacctgcgc
aagcccaagagcatgcacaagcgattcttcgtgctgcgggcggccagcgaggcggggggc
ccggcgcgcctcgagtactacgagaacgagaagaagtggcggcacaagtcgagcgccccc
aaacgctcgatccccctcgagagctgcttcaacatcaacaagcgggccgactccaagaac
aagcacctggtggccctctatacccgggacgagcactttgccatcgcggcggacagcgag
gccgagcaggacagctggtaccaggccctcctgcagctgcacaaccgtgccaagggccac
cacgacggggccgcggcccccggggcgggaggcggcgggggcagctgcagtggcagctcc
ggccttggcgaggctggggaggacttgagctacggggacgtgcccccaggacccgccttc
aaggaagtctggcaggtgatcctgaaacccaagggcctgggtcagacaaagaacctgatt
ggcatctaccgcctctgcctgaccagcaagaccatcagcttcgtgaagctgaactcggag
gctgccgcggtggtgctgcagctgatgaacatcaggcgctgtggccactcagagaacttc
ttcttcatcgaagtgggccgttccgcagtgacgggacccggggagttctggatgcaggtg
gatgactctgtggtggcccagaacatgcacgagacgatcttggaagccatgcgggccatg
agcgatgagttccgccctcgaagcaagagccagtcctcctccaactgctccaaccccatc
agtgtccccctgcgcaggcatcacctcaacaaccctccacccagccaggtggggctgacc
cgccgctcgcgcacagagagcatcactgccacctccccggccagcttggtgggcgggaag
cagggctccttccgggtccgcgcctctagtgatggcgaaggcaccatgtctcgccctgcc
tctgtggacggcagtcctgtgagtcccagcaccaacaggacccatgcccaccggcatcgg
ggcagttcccggctgcacccgcctctcaaccacagccgctccatccccatgccttcttct
cgctgctcgccttccgccaccagcccggtcagtctatcgtccagtagcaccagtggccac
ggctccacctcggactgtctcttcccgcggcggtctagtgcttccgtgtccggttccccc
agtgatggcggtttcatctcctctgatgagtatggctccagtccctgcgacttccgaagt
tccttccgcagtgtcaccccggattccctgggccacaccccgccggcccgcggtgaggag
gaactgagcaactacatctgcatgggaggcaagggggcctccaccctcacggcccccaat
ggtcactacattttgcctcggagtggcaacggtccccgctacatcccggcagccggcttg
ggcacgagcccagccctgacaggggatgaagcagctagtgctgcagatctggacaatcgg
ttccgaaagcggactcactctgctggcacgtcacctaccatttcccaccagaagacccca
tcccagtcttctgtggcctccattgaggaatataccgagatgatgcctgcctacccacca
ggaggtggcagtggaggccgagtgcccagctaccggcactccgccttcgtgcccacccac
tcctacccagaggagggtctggaaatgcaccccttggagcggcgtgtgggccaccaccgc
ccagacacctccaacctccacaccgatgatggctacatgcccatgtccccaggggtggcc
ccagtgcccgggagccgaaagggcagtggggactacatgcccatgagccccaagagcgtg
tctgcccctcagcagatcatcaaccccatcagacgccatccccagagagtggaccccaat
ggctacatgatgatgtccccaagcggcagctgctctcctgacattggaggcgggcccagc
agcggcggcagcagcggtgccgccccttctgggagcagctatggcaagctctggacgaat
ggggtagggggccaccactctcacgccctgccacaccccaaactccctgtggagagcagt
agcggcaagctgttgtcttgtacgggtgactacatgaacatgtcgccagtgggagactcc
aacaccagcagcccttccgactgctactatggccctgaggacccccagcacaagccagtc
ctctcctactactcattgccaaggtcctttaagcacacccagcgccccggggagctggag
gagggcgcccggcaccagcaccaccgcctttcctccagctcgggtcgactcctctatgct
gcggcggcggaagattcctcctcgtccaccagcagcgacagcctgggcgggggatactgc
gcggctaggcccgagcccggcctcccgcatctccaccatcaggtcctgcagccccatctg
cctcgaaaggtggacacagctgcccagaccaacagccgcctggcccggcccacgaggctg
tccctgggggaccccaaggccagcaccttaccccgggcccgagagcagccgcagccccag
ccgcagccgccaccgcccctgctgccccctccggagcccaagagcccaggggaatatgtg
aatattgaatttgggagcgatcagccgggctacttatcaggcccgggggcttcccacagc
tcgccttctgtccggtgtccatcccagctccagccggctcccagagaggaggagacgggc
gcggaagagtacatgaacatggacctggggccgggccggagggccgcctggcgggagagc
cccggggtccagccgggcagcatgggcccggcaccccctggagctgctagcgtgtgcagg
cccaccagggcagtgcccagcagccggggtgactacatgaccatgcagatgggctgtccc
cggcagagctacgtggacacctcgccagtcgcccccatcagctatgcggacatgcggacc
ggcagcggcagcggcctcgtggaggaggccagcctgcctggggccgccgcggccacgccc
tcctcatcctcgaaggcctctgcttcccccgccgcgcctcaaggagcagaggagctggcg
gcccgctcttccctgctggggggcccgcagggacccgggggctcgagtgccttcacgcgg
gtgaacctcagtcccaaccgcaaccagagtgccaaagtgatccgtgccgacccgcaaggg
tgcaggaggcggcacagctccgagaccttctcctcgacgcccagtgccacccgggcaggc
aacacggtgcccttcggagggggggctgcagccgggggcggcggtggtggcagcagcagc
acggaggacgtgaaacgccacagctctgcttcctttgagaacgtgtggctgcggcctggg
gagctcgggggagcccccaaggagctggcccaagtgtgcggggccaccgggggtttggag
aatgggcttaactacatagacctggatttggtcaaggacttcaaccagagccctcaagag
cgtcccgctccgccgcagccttctcctcccccaccccctcatcagcctctgggacgcagc
gagggcggctccaccagccgctccagcgaggatttaagcgcctatgccagcatcagtttc
cagaagccgccagaggacctccagtag
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