Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise): 112397998
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Entry
112397998 CDS
T08872
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein isoform X1
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
nasi
Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)
Pathway
nasi01524
Platinum drug resistance
nasi03440
Homologous recombination
nasi03460
Fanconi anemia pathway
nasi04120
Ubiquitin mediated proteolysis
nasi04151
PI3K-Akt signaling pathway
nasi05206
MicroRNAs in cancer
nasi05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
nasi00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
112397998 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
112397998 (BRCA1)
03460 Fanconi anemia pathway
112397998 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
112397998 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
112397998 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
112397998 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
112397998 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
nasi01009
]
112397998 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
nasi04121
]
112397998 (BRCA1)
03036 Chromosome and associated proteins [BR:
nasi03036
]
112397998 (BRCA1)
03400 DNA repair and recombination proteins [BR:
nasi03400
]
112397998 (BRCA1)
Enzymes [BR:
nasi01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
112397998 (BRCA1)
Protein phosphatases and associated proteins [BR:
nasi01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
112397998 (BRCA1)
Ubiquitin system [BR:
nasi04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
112397998 (BRCA1)
Multi subunit type E3
BRCC complex
112397998 (BRCA1)
Chromosome and associated proteins [BR:
nasi03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
112397998 (BRCA1)
DNA repair and recombination proteins [BR:
nasi03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
112397998 (BRCA1)
BRCA1-A complex
112397998 (BRCA1)
BRCA1-B complex
112397998 (BRCA1)
BRCA1-C complex
112397998 (BRCA1)
BRCA complex
112397998 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
112397998 (BRCA1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-C3HC4_2
zf-RING_UBOX
zf-C3HC4_4
zf-RING_2
zf-C3HC4_3
zf-RING_5
RING_XB3-XBAT31
zf-RING_6
BRCT_2
zf-ANAPC11
zf-Nse
zf-RING_10
zf-rbx1
Prok-RING_4
Motif
Other DBs
NCBI-GeneID:
112397998
NCBI-ProteinID:
XP_024598135
UniProt:
A0A341B5Q8
LinkDB
All DBs
Position
Unknown
AA seq
1870 aa
AA seq
DB search
MDFSANHVEEVQNVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
CPLCKNDVTRRSLQESTRFSQLVEELLKIIHAFELDTGLQIANSYNFSKKENNSPEHLKE
EVSIIQSMGYRNRAKRLQQSEPENPTLQGTSLSVQLSNLGIVRSLRTKQQIQPQNKSVYI
ELGSDSSEDTVNKASYFSVEDHELLEITPQGAKAEASLNRAKKAACEFSEKDITKAEHHQ
FSNKDLTTTEKHETEKHPEKYQGIFVSNLHVEPCGTDTHASSLQHENSSLLLTKDRMNVE
KAEFCNKSKQLVLGKSQQSRWAESKDTCNDRQTPSTEKKVVLNADPLYGRKELNKQKPAS
SDSPRDSQEFPWITLNSSIQKVNEWFSRSDEMLTSYDSRDGGFESNTGVARAVEVPKEVD
GYLGSSEKIDLMASDPHGALIRERVHAKPVESNIEDKIFGKTYQRKASLPNLSRIAEDLI
IGASTVEPQITQERPLTKKLQRKRRSTSGLHPEDFIKKVDLAVLPKTPENIIEGTDQTEQ
NGHGMNITSNGHETEMKGGNVQKEKNANRTESLEKESAFRTKAEPISSSISNMELELNIH
SSKAPKNRLRRKSSTRNIHALELVVSRNPSPPNHTELQIESCSSSEEMKKKHSSQMPVRH
GKKLQFMGDKEPTPGAKKSDKPHEQITKRLASDTYPELNLTNIPVFFTHCSSSNKLQEFV
NPSLQREESLGTIQVSNNTKDPKDLTLSGGKGLQIERYVESTSISLVPDTDYGTQDSTSL
LEADTLGKAKTAPNQHVSLCAAIESPKELIPGCSKDIRNDTEDFQDPLGHDVNHIQKASI
EMEESELDTQYLQNMFKVSKRQTFALFSNPENPEKECATVCAHSGSLWEQSPRVPLECRQ
KEENQGKSESKVKHVRAINTTVDFPVAGQKDKKPSGHAKCSPERVTRLCQSSQFRGNKTE
LIIANKHGISHNPYLIPSLSPIRSSVKTICKKNLSEEKFEEPVMSPERAMENESIVQSTV
CTVSQNNSRESTFKEVSSSSIHEVGSSTNEVGSSINEVGSSGENIQAKLDRNRGPKLSAL
LRLGLMQPEVYKQSLPVSNCQLPEIKRQGENEGTLQAVNEDFSPCLNSDNLEQPMGRSHA
SQVCSETPDELLNDDKIKESSNFAESDIKERSAVFSKGVQKGEFRRSPGPLAHHTPLVQG
HERGAESSEENVSSEDEELPCFQHLFGKVTNTLSPSTRRNAVATEGLSKETEENLISLKN
SLNDCSDHVTSAKASQEHHLHEEVRCSDSLFSSRCSVVEDLTANTNTQDPFLMFDPLSKQ
VGHQSENQEVLSDKELVSDDDERETGWEEDNRQEEQSVDSDLGEAASEYENETSLSEDCL
GLSSQSDILTTQQRDTMQDNLLKIQQEMAELEAVLEQHGSQPSHSSPSLIADSCASEDLL
NLEQNTSEKAVLTSEKSSEYPISRNPESLSADKFQVSPDTSTSKNKEPGMERSSPSKLQL
SDNSWYMHSHSRSLQNRNCPPQKELEVVDVEEQQLTESEAQDLMEQSSLPRQDLEGTPYL
ESGISLFSDDPESDPSEDRTPEPAHVCSMPPSASALKLPQFQVVESARSPATSHTTNTAG
YNVREESVSREKPELIPSTQRGNKRISMVASGLTPKEFVLVHKFARKHHITLTNLITEET
THVIMKTDAEFVCERTLKYFLGIAGGRWVVSYFWVTQSIKERKMLDEHDFEVRGDVVNGR
NHQGPKRARESQDRKIFKGLEICCYGPFTNMPTDQLEWMVRLCGASVVKEPSSFTLSQGT
QPIVVVQPDAWTEGGGFHGESCFIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQVPR
AAADSSLPCI
NT seq
5613 nt
NT seq
+upstream
nt +downstream
nt
atggatttttctgcgaatcacgttgaagaagtacaaaatgtccttaatgctatgcagaaa
atcttagagtgtccaatctgtctggagttgatcaaagagcctgtttccacaaagtgtgat
cacatattttgcaaattttgtatgctgaaacttctcaaccagaagaaagggccttcacag
tgtcctttgtgtaagaatgatgtaaccagaagaagcctacaagaaagtacaagatttagt
cagcttgttgaagagctattgaagatcattcatgcttttgagcttgacacaggattgcag
attgcaaacagttataacttttcaaaaaaggaaaataactctcctgagcatctaaaggag
gaagtttctatcattcaaagtatgggctaccgaaaccgggccaaaagacttcagcagagt
gaacctgaaaatcctaccttgcagggaaccagtcttagtgtccagctctctaaccttgga
attgtgagatctctgaggacaaagcagcagatacaacctcaaaataagtccgtctacatt
gaattgggatctgattcttctgaagatacagttaataaggccagttatttcagtgtagaa
gaccatgaattgttagaaatcacccctcaaggagccaaggctgaagccagtttgaatcgt
gcaaaaaaggctgcttgtgagttttctgagaaggacataacaaaggctgaacatcatcaa
ttcagtaataaagatttgaccaccactgagaagcatgaaactgagaagcatccagaaaag
tatcagggtatttttgtttcaaacttgcatgtggagccatgtggcacagatactcatgcc
agctcattacagcatgaaaacagcagtttattactcactaaagacagaatgaatgtagaa
aaggctgaattctgtaataaaagcaaacagcttgtcttaggaaagagccaacagagcaga
tgggctgaaagtaaggacacatgtaatgataggcagactcccagtacagagaaaaaggta
gttctgaatgctgatcccctatatgggagaaaagaactgaataagcagaaacctgcatcc
tctgacagtcctagagattcccaagagtttccttggataacactgaatagtagcatacag
aaagttaatgaatggttttccagaagtgatgaaatgttaacttcttacgactcacgtgat
gggggatttgaatcaaacactggagtagctcgtgcagtggaagttccaaaggaagttgat
ggatatttgggttcttcagagaaaatagacttaatggccagtgatcctcatggtgcttta
atacgtgaaagagtccacgccaaaccagtagagagtaatattgaagataaaatatttggg
aaaacctatcagaggaaggcaagcctccctaacttgagccgcatagctgaagatctaatt
ataggagcatctactgtagaacctcagataacacaagagcgccccctcacaaaaaaacta
cagcgtaaaaggagaagtacatcaggccttcatcctgaggattttatcaagaaagtcgat
ttggcagttcttccaaagactccagaaaacataattgagggaactgaccaaacagagcag
aatggtcatgggatgaatattactagtaatggtcatgagactgaaatgaaaggtggtaat
gttcagaaagagaaaaatgctaaccgaacagaatcattggaaaaagaatctgctttcaga
actaaggctgaacctataagcagcagtataagcaatatggaactagaattgaatatccat
agttcaaaagcacctaaaaataggctgaggaggaagtcctctaccaggaacattcatgca
cttgaactagtagtcagtagaaacccaagcccacctaatcatactgaactacaaattgaa
agttgttctagcagtgaagagatgaagaaaaaacattccagccaaatgccagtcaggcac
ggcaaaaagcttcaattcatgggagataaagaacctacacctggagccaagaagagtgac
aagccacacgaacaaataactaagagacttgccagtgacacttacccagaactaaatttg
acaaacatacctgtcttttttactcactgttccagttctaataaacttcaagagtttgtt
aatcctagccttcaaagagaggagagcctaggaacaattcaagtgtcgaataataccaaa
gaccccaaagatctgacattaagtggaggaaaaggtttgcaaattgaaagatatgtagag
agtaccagtatttccttggtacctgatactgattatggcactcaggatagtacctcatta
ctggaagctgacaccctagggaaggcaaagacagcaccaaaccaacatgtgagtctgtgt
gcagctattgaaagccccaaggaacttatccctggttgttctaaagatattagaaacgac
acagaggactttcaggatccactgggacatgacgttaaccacattcagaaggcgagcata
gaaatggaagagagtgaacttgatacacagtatttgcagaatatgttcaaggtttcaaag
cgtcagacgtttgctctgttttcaaatccagaaaatccagaaaaggaatgtgcaacagtc
tgtgcccactctgggtccttatgggaacaaagtccaagagtccctcttgaatgcagacaa
aaagaagaaaatcagggaaagagtgagtctaaagtcaagcatgtgcgggcaattaataca
actgtggacttccctgtcgctggtcaaaaagataagaagccgagcggtcatgccaaatgt
agcccagaaagagtaactaggctttgtcagtcatcacagttcagaggcaacaaaactgag
ctcattattgcaaataaacatgggatttcacacaacccatatcttataccatcactttct
cccatcaggtcatctgttaaaactatatgtaagaaaaacctgtcagaggaaaagtttgag
gaacctgtaatgtcacctgaaagagcaatggaaaacgagagcatcgttcaaagtacagtg
tgcacggttagccaaaataacagtcgagaaagcacttttaaagaagtcagctcaagcagt
attcatgaagtaggttccagtactaatgaagtaggctctagtattaatgaagtaggttcc
agtggtgaaaacattcaagcaaaactagatagaaacagaggacctaaattaagtgctttg
ctcagattaggtcttatgcaacccgaagtctataagcaaagtcttcctgtaagtaactgt
caacttcctgaaataaaaaggcaaggagaaaatgaaggcacacttcaggctgttaatgaa
gatttctccccatgtctaaattcagataacctagaacaacctatgggaagaagccatgct
tctcaggtttgttctgagacacctgatgagttgttaaatgatgacaaaataaaggaaagt
agcaactttgctgaaagtgacattaaggaaagatctgctgtttttagcaaaggtgtccaa
aaaggagaattcagaaggagccctggccctttagcccatcatacacctttggttcagggt
cacgaaagaggggctgagtcctcagaagagaatgtgtctagcgaggatgaagagcttccc
tgcttccagcacttatttggtaaagtaaccaatacactgtctccatctaccagacgtaat
gctgttgccacagagggtctatctaaggaaacagaggagaatctaatatcattgaagaat
agtttaaatgactgcagtgaccacgtaacatcggcaaaggcatcccaggaacatcacctt
cacgaggaagtgagatgttctgatagcttattttcttcacggtgcagtgtagtggaagac
ttgaccgctaatacaaacacccaggatcctttcttgatgtttgatcctctttccaaacaa
gtggggcatcagtctgaaaaccaggaagttctgagtgacaaggaattggtttcagatgat
gatgaaagggaaactggctgggaagaggataatcgccaagaagagcagagtgtggattca
gacttaggtgaagcagcatccgagtatgagaatgaaacaagcctctctgaagactgtttg
gggctgtcctctcagagcgatatcttaaccactcagcagagggataccatgcaagataac
ctgctaaagatccagcaggaaatggccgaactggaagctgtgttagagcagcacgggagc
cagccttctcacagctccccttccctcatagccgattcttgtgcctctgaggacctgcta
aatctggagcaaaacacatcagaaaaagcagtattaacttcagagaaaagtagtgaatat
cctataagccggaatccagaaagcctttctgctgacaagtttcaagtatctccagatact
tccaccagtaaaaataaagaaccaggaatggaaaggtcttccccttctaaattgcagttg
tcagataatagttggtatatgcacagccactcaaggagtcttcagaacagaaactgccca
cctcaaaaggagcttgaggttgttgatgtggaggagcaacagctgacggagtctgaggcc
caggatttaatggagcagtcttctttgccaagacaagatctagagggaaccccttaccta
gaatctggaatcagcctcttctctgatgaccctgagtctgatccctctgaagacagaacc
ccagagccagctcatgtctgcagcatgccaccctcagcctctgcactgaaattaccccaa
tttcaagtagtagaatctgccaggagtccggctacatctcatactactaatactgcaggg
tataatgtgagggaagaaagtgtgagcagggagaagccagagttgataccttcaacacaa
agaggcaacaaaagaatttctatggtggcatcaggcttgaccccaaaagaatttgtgctt
gtgcacaagtttgccagaaaacaccacatcactttaactaatctaattactgaagagact
actcatgtcattatgaaaacagatgctgagtttgtgtgtgaacggacactgaaatatttt
ctgggaattgcaggaggaagatgggtagttagctatttctgggtgacccagtctatcaaa
gaaagaaagatgctggatgagcatgattttgaagtcagaggcgatgttgtcaatggaaga
aaccatcaaggcccaaagcgagcaagagaatcccaggacaggaagatcttcaagggctta
gaaatctgttgctatggaccatttaccaatatgcccacagatcaactagagtggatggta
cgtctgtgtggggcttctgtggtgaaggagccctcatcattcaccctcagccagggtact
caaccaattgtggtcgtgcagccggatgcctggacagagggcggtggcttccatggtgag
tcttgcttcatcgggcagatgtgtgaagcacctgtggtgacccgagagtgggtattggac
agcgtagccctctaccagtgccaggagctggacacctacctgataccccaggtccccaga
gctgctgctgattccagcctgccatgtatatag
DBGET
integrated database retrieval system
